about
NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathwaysMixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complexThe net repressor is regulated by nuclear export in response to anisomycin, UV, and heat shockActivation of IkappaB kinase beta by protein kinase C isoformsThe ectodermal dysplasia receptor activates the nuclear factor-kappaB, JNK, and cell death pathways and binds to ectodysplasin ANF-kappaB activation through IKK-i-dependent I-TRAF/TANK phosphorylationERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-kappaBTACE/ADAM17-TNF-alpha pathway in rat cortical cultures after exposure to oxygen-glucose deprivation or glutamateMouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaBAssociations Among -TrCP, an E3 Ubiquitin Ligase Receptor, -Catenin, and NF- B in Colorectal CancerHepatitis C virus core protein enhances NF-kappaB signal pathway triggering by lymphotoxin-beta receptor ligand and tumor necrosis factor alpha.Proteasome-independent activation of nuclear factor kappaB in cytoplasmic extracts from human endothelial cells by Rickettsia rickettsiiATM: a mediator of multiple responses to genotoxic stress.Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.Mapping of a serine-rich domain essential for the transcriptional, antiapoptotic, and transforming activities of the v-Rel oncoprotein.NOD mice are defective in proteasome production and activation of NF-kappaBNF-κB in the mechanism of brain edema in acute liver failure: studies in transgenic mice.NF-kappaB signaling proteins as therapeutic targets for inflammatory bowel diseases.Identification of gene function and functional pathways by systemic plasmid-based ribozyme targeting in adult miceRole of nuclear factor-kappa B (NF-kappa B) in inflammation, periodontitis, and atherogenesis.Statistical ensemble analysis for simulating extrinsic noise-driven response in NF-κB signaling networks.Bortezomib induces nuclear translocation of IκBα resulting in gene-specific suppression of NF-κB--dependent transcription and induction of apoptosis in CTCL.Thyroid hormone, T3-dependent phosphorylation and translocation of Trip230 from the Golgi complex to the nucleus.Ozone as Janus: this controversial gas can be either toxic or medically useful.Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-kappaB regulated gene products.Different mechanisms for suppression of apoptosis by cytokines and calcium mobilizing compoundsProteasome inhibitors induce apoptosis of prostate cancer cells by inducing nuclear translocation of IkappaBalpha.NFkappaB in the mechanism of ammonia-induced astrocyte swelling in culture.Regulation and function of nuclear IκBα in inflammation and cancerEssential role of human leukocyte antigen-encoded proteasome subunits in NF-kappaB activation and prevention of tumor necrosis factor-alpha-induced apoptosis.The alpha-helical D1 domain of the tobacco bZIP transcription factor BZI-1 interacts with the ankyrin-repeat protein ANK1 and is important for BZI-1 function, both in auxin signaling and pathogen response.Curcumin suppresses colon cancer cell invasion via AMPK-induced inhibition of NF-κB, uPA activator and MMP9.Nuclear factor κB down-regulates human UDP-glucuronosyltransferase 1A1: a novel mechanism involved in inflammation-associated hyperbilirubinaemia.Transcriptional cross talk between NF-kappaB and p53.Brain-derived neurotrophic factor protects cementoblasts from serum starvation-induced cell death.Curcumin improves expression of SCF/c-kit through attenuating oxidative stress and NF-κB activation in gastric tissues of diabetic gastroparesis rats.Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion.Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasionProtein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis.
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
IkappaB kinase: beginning, not the end
@ast
IkappaB kinase: beginning, not the end
@en
type
label
IkappaB kinase: beginning, not the end
@ast
IkappaB kinase: beginning, not the end
@en
prefLabel
IkappaB kinase: beginning, not the end
@ast
IkappaB kinase: beginning, not the end
@en
P2860
P356
P1476
IkappaB kinase: beginning, not the end
@en
P2093
J Stevenson
P2860
P304
11758-11760
P356
10.1073/PNAS.94.22.11758
P407
P577
1997-10-01T00:00:00Z