DNA polymerase zeta is required for proliferation of normal mammalian cells.
about
Mechanism of suppression of chromosomal instability by DNA polymerase POLQA protein prioritization approach tailored for the FA/BRCA pathway.Spartan deficiency causes genomic instability and progeroid phenotypes.REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζHuman REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome.The Polymerase Activity of Mammalian DNA Pol ζ Is Specifically Required for Cell and Embryonic Viability.De novo mutations in PLXND1 and REV3L cause Möbius syndromeDual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses.Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint.DNA damage tolerance and a web of connections with DNA repair at Yale.DNA polymerase ζ limits chromosomal damage and promotes cell survival following aflatoxin exposure.Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools.PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome.A missense mutation in Rev7 disrupts formation of Polζ, impairing mouse development and repair of genotoxic agent-induced DNA lesions.Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass.Breakthrough for a DNA break-preventer.REV1 and DNA polymerase zeta in DNA interstrand crosslink repair.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Translesion DNA synthesis and mutagenesis in eukaryotesPrimPol-A new polymerase on the block.Polymerase ζ Activity Is Linked to Replication Timing in Humans: Evidence from Mutational Signatures.Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy?Rev3, the catalytic subunit of Polζ, is required for maintaining fragile site stability in human cells.Around and beyond 53BP1 Nuclear Bodies.The CysB motif of Rev3p involved in the formation of the four-subunit DNA polymerase ζ is required for defective-replisome-induced mutagenesis.MicroRNA-340 inhibits the proliferation and promotes the apoptosis of colon cancer cells by modulating REV3L.
P2860
Q28543483-59A017BD-3437-4628-8C83-17D2D2CD08ABQ34689369-204F34D3-5245-4E5B-BF7F-CE31ED1F7463Q34722436-93C803E7-83D5-41E9-B4B2-509B76406120Q35098093-F729B13F-39AC-4349-9B3F-A4CCD64BDCD6Q35804949-E8AD66AF-402E-4399-8B03-30F2B4058F7FQ35884176-5DD551DF-2BF7-40C2-9DDB-EA59ECBE60E4Q36287506-D801F43E-96FE-427F-BF05-73D8CBF8C73DQ36637565-DE9871D1-922F-470F-A688-5F727724DAEEQ36668832-C3C3A6A1-0AC0-4BF8-8302-6CD7AE01484AQ37358566-03A6A39B-B6DE-4B6D-B0B9-1A9C4B02A971Q37473700-F7D4354C-FF0E-466A-B077-C4A284730225Q37483304-FF05E367-FB0F-4CB1-A0E0-B16279B4DA5DQ37504432-FC13E94B-CDE9-49F0-A1C7-57C04D439B2BQ37563590-8ADFE9C5-5994-48F0-A879-6DE7A478B240Q37612640-AED7D1E9-6A90-45BD-A6EF-3F3919FE9B02Q37612668-0A1C9209-F7FC-44BD-A87B-AC1D84BF3577Q38052100-43544C0B-CF32-4E3C-9586-0570402E29CDQ38063711-27328EBE-CABA-44EE-ACB0-D74CF6000609Q38086224-F36021CC-FF67-4AA1-BC06-984CE5D98282Q38866687-DE1E4BCC-0B3F-461F-8D27-9410BBF6F56CQ40533204-6BD1FDEA-8B51-4AB9-90AD-F129BF651068Q41443583-E183AF5F-3356-4EFD-91A4-1D2169516143Q42171732-E66C4A2E-4D57-4DDC-B5DD-6B565560F87AQ47186808-2C548A72-BEF9-4847-9460-D8469D2E3EA9Q47755642-18898D6A-8256-4838-B585-D02A31F33689Q49779139-E3273117-8230-4D1F-8A33-AB800B6C23EC
P2860
DNA polymerase zeta is required for proliferation of normal mammalian cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
DNA polymerase zeta is required for proliferation of normal mammalian cells.
@ast
DNA polymerase zeta is required for proliferation of normal mammalian cells.
@en
type
label
DNA polymerase zeta is required for proliferation of normal mammalian cells.
@ast
DNA polymerase zeta is required for proliferation of normal mammalian cells.
@en
prefLabel
DNA polymerase zeta is required for proliferation of normal mammalian cells.
@ast
DNA polymerase zeta is required for proliferation of normal mammalian cells.
@en
P2860
P356
P1476
DNA polymerase zeta is required for proliferation of normal mammalian cells.
@en
P2093
John P Wittschieben
Sabine S Lange
P2860
P304
P356
10.1093/NAR/GKS054
P407
P577
2012-02-07T00:00:00Z