Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding.
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Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitisInternational Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyNeural control of the lower urinary tractHow does the urothelium affect bladder function in health and disease? ICI-RS 2011Authentic role of ATP signaling in micturition reflex.Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2CTransient receptor potential channels as therapeutic targetsArresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4The TRPV4 channel contributes to intercellular junction formation in keratinocytesTRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasisCellular and Molecular Mechanisms of PainSpontaneous voiding by mice reveals strain-specific lower urinary tract function to be a quantitative genetic traitUrothelial signaling.Nociceptive and pro-inflammatory effects of dimethylallyl pyrophosphate via TRPV4 activation.TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells.A novel subtype of astrocytes expressing TRPV4 (transient receptor potential vanilloid 4) regulates neuronal excitability via release of gliotransmitters.The puzzle of TRPV4 channelopathies.Transient receptor potential (TRP) channels: a clinical perspectiveTRP channels in lower urinary tract dysfunction.Release of ATP from rat urinary bladder mucosa: role of acid, vanilloids and stretchCell biology and physiology of the uroepithelium.Emerging Families of Ion Channels Involved in Urinary Bladder Nociception.Functional role for Piezo1 in stretch-evoked Ca²⁺ influx and ATP release in urothelial cell cultures.Functional characterization of transient receptor potential channels in mouse urothelial cells.Mice expressing mutant Trpv4 recapitulate the human TRPV4 disordersIntravesical TRPV4 blockade reduces repeated variate stress-induced bladder dysfunction by increasing bladder capacity and decreasing voiding frequency in male ratsPannexin 1 channels play essential roles in urothelial mechanotransduction and intercellular signalingBladder sensory physiology: neuroactive compounds and receptors, sensory transducers, and target-derived growth factors as targets to improve function.Deletion of Dicer in smooth muscle affects voiding pattern and reduces detrusor contractility and neuroeffector transmissionExpression and distribution of transient receptor potential (TRP) channels in bladder epithelium.Receptors, channels, and signalling in the urothelial sensory system in the bladderIP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site.New insights into the pharmacology of the bladderTRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells.Prospective pharmacologic therapies for the overactive bladderDeciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron.Evaluation of voiding assays in mice: impact of genetic strains and sex.Vesicular and conductive mechanisms of nucleotide release.Changes in voiding behavior in a mouse model of Alzheimer's disease.Afferent nerve regulation of bladder function in health and disease.
P2860
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P2860
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Deletion of the transient rece ...... mpairs murine bladder voiding.
@ast
Deletion of the transient rece ...... mpairs murine bladder voiding.
@en
type
label
Deletion of the transient rece ...... mpairs murine bladder voiding.
@ast
Deletion of the transient rece ...... mpairs murine bladder voiding.
@en
prefLabel
Deletion of the transient rece ...... mpairs murine bladder voiding.
@ast
Deletion of the transient rece ...... mpairs murine bladder voiding.
@en
P2093
P2860
P50
P356
P1476
Deletion of the transient rece ...... mpairs murine bladder voiding.
@en
P2093
Andrei Segal
Thomas Gevaert
Wolfgang Liedtke
Wouter Everaerts
P2860
P304
P356
10.1172/JCI31766
P407
P50
P577
2007-11-01T00:00:00Z