Human POLB gene is mutated in high percentage of colorectal tumors.
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MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNAGut Microbiota Imbalance and Base Excision Repair Dynamics in Colon CancerTumor-specific microsatellite instability: do distinct mechanisms underlie the MSI-L and EMAST phenotypes?DNA polymerase delta in DNA replication and genome maintenanceThe E295K Cancer Variant of Human Polymerase Favors the Mismatch Conformational Pathway during Nucleotide SelectionDNA Polymerases λ and β: The Double-Edged Swords of DNA RepairDNA polymerase β contains a functional nuclear localization signal at its N-terminus.The S229L colon tumor-associated variant of DNA polymerase β induces cellular transformation as a result of decreased polymerization efficiency.Irreversible inhibition of DNA polymerase β by small-molecule mimics of a DNA lesionA Change in the Rate-Determining Step of Polymerization by the K289M DNA Polymerase β Cancer-Associated VariantSequence context modulation of polycyclic aromatic hydrocarbon-induced mutagenesis.Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.Substrate-induced DNA polymerase β activation.Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotideTumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase.Substrate-dependent millisecond domain motions in DNA polymerase β.Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation.Synergistic Effects of an Irreversible DNA Polymerase Inhibitor and DNA Damaging Agents on HeLa Cells.Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaksTranscriptional profiling reveals elevated Sox2 in DNA polymerase ß null mouse embryonic fibroblasts.Evidence-based Guidelines for Precision Risk Stratification-Based Screening (PRSBS) for Colorectal Cancer: Lessons learned from the US Armed Forces: Consensus and Future Directions.The structural location of DNA lesions in nucleosome core particles determines accessibility by base excision repair enzymesSite-specific Acetylation of Histone H3 Decreases Polymerase β Activity on Nucleosome Core Particles in VitroEpistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicityCatalytic effects of mutations of distant protein residues in human DNA polymerase β: theory and experiment.Substrate rescue of DNA polymerase β containing a catastrophic L22P mutation.Cellular roles of DNA polymerase beta.DNA Polymerase Beta Germline Variant Confers Cellular Response to Cisplatin Therapy.Base excision repair of oxidative DNA damage: from mechanism to disease.DNA polymerase β promoter mutations and transcriptional activity in esophageal squamous cell carcinoma.Genome instability caused by a germline mutation in the human DNA repair gene POLB.DNA Polymerase β Cancer-Associated Variant I260M Exhibits Nonspecific Selectivity toward the β-γ Bridging Group of the Incoming dNTP.Defective Nucleotide Release by DNA Polymerase β Mutator Variant E288K Is the Basis of Its Low Fidelity.Role of Conformational Motions in Enzyme Function: Selected Methodologies and Case Studies.Base Excision Repair Variants in Cancer.
P2860
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P2860
Human POLB gene is mutated in high percentage of colorectal tumors.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Human POLB gene is mutated in high percentage of colorectal tumors.
@ast
Human POLB gene is mutated in high percentage of colorectal tumors.
@en
type
label
Human POLB gene is mutated in high percentage of colorectal tumors.
@ast
Human POLB gene is mutated in high percentage of colorectal tumors.
@en
prefLabel
Human POLB gene is mutated in high percentage of colorectal tumors.
@ast
Human POLB gene is mutated in high percentage of colorectal tumors.
@en
P2093
P2860
P356
P1476
Human POLB gene is mutated in high percentage of colorectal tumors.
@en
P2093
Antonia A Nemec
Daniel Zelterman
Drew L Murphy
Joann B Sweasy
Ka-wai Sun
Katherine A Donigan
Veronika Northrup
Xiangyu Cong
P2860
P304
23830-23839
P356
10.1074/JBC.M111.324947
P407
P577
2012-05-10T00:00:00Z