Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia. - Wikidata - wikimedia - TriplyDB

Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia.

Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia.

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Aberrant Promoter Hypomethylation in CLL: Does It Matter for Disease Development?The role of epigenetics in the endothelial cell shear stress response and atherosclerosis Genomic and epigenomic heterogeneity in chronic lymphocytic leukemia Emerging technologies for studying DNA methylation for the molecular diagnosis of cancer Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis A full Bayesian partition model for identifying hypo- and hyper-methylated loci from single nucleotide resolution sequencing data.Genome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemia Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis.Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis.Coordinated epigenetic remodelling of transcriptional networks occurs during early breast carcinogenesis.Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells.An evaluation of methods to test predefined genomic regions for differential methylation in bisulfite sequencing data.New DNA Methylation Markers for Pancreatic Cancer: Discovery, Tissue Validation, and Pilot Testing in Pancreatic Juice Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing Identification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem Cells.Epigenetic and genetic alterations and their influence on gene regulation in chronic lymphocytic leukemia.NFAT as cancer target: mission possible?Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia.Profiling the genome-wide DNA methylation pattern of porcine ovaries using reduced representation bisulfite sequencing Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics Personalized medicine in CLL: current status and future perspectives.The expression of RUNDC3B is associated with promoter methylation in lymphoid malignancies Uncovering the DNA methylome in chronic lymphocytic leukemia.Molecular pathogenesis of CLL and its evolution.DNA methylation protects against cisplatin-induced kidney injury by regulating specific genes, including interferon regulatory factor 8.Promoter Methylation Modulates Indoleamine 2,3-Dioxygenase 1 Induction by Activated T Cells in Human Breast Cancers.RPPA-based protein profiling reveals eIF4G overexpression and 4E-BP1 serine 65 phosphorylation as molecular events that correspond with a pro-survival phenotype in chronic lymphocytic leukemia.Coevolution of Leukemia and Host Immune Cells in Chronic Lymphocytic Leukemia.Wnt signalling pathways in chronic lymphocytic leukaemia and B-cell lymphomas.dbEM: A database of epigenetic modifiers curated from cancerous and normal genomes.EpiDBase: a manually curated database for small molecule modulators of epigenetic landscape.Corrigendum: Identification of a 5-Methylcytosine Site that may Regulate C/EBPβ Binding and Determine Tissue-Specific Expression of the BPI Gene in Piglets.Alterations in DNA methylation/demethylation intermediates predict clinical outcome in chronic lymphocytic leukemia 450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments.A method to detect differentially methylated loci with next-generation sequencing.NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib.Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten.Chronic lymphocytic leukaemia

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Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia.

http://www.wikidata.org/entity/Q36100977

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Genome-wide DNA methylation an ...... chronic lymphocytic leukemia.

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Brian McCarthy

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Charles Caldwell

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David H Munn

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Dong Xu

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Ethan Speir

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Eun-Joon Lee

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Farrukh Awan

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Gerald Arthur

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Han-Fei Ding

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Hongseok Tae

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Genome-scale DNA methylation maps of pluripotent and differentiated cells

Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia

Promoter hypermethylation silences expression of the HoxA4 gene and correlates with IgVh mutational status in CLL

TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia

Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus

Epigenetics in cancer

Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities.

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms

The DNA methylome of human peripheral blood mononuclear cells

Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway.

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567-578

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10.4161/EPI.20237

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6

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7

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22534504

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DNA methylation

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3398986

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