Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration. - Wikidata - wikimedia - TriplyDB

Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration.

Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration.

http://www.wikidata.org/entity/Q36102995

about

Do nutritional supplements have a role in age macular degeneration prevention?Inflammation and its role in age-related macular degeneration Microglia in the outer retina and their relevance to pathogenesis of age-related macular degeneration Genetics of immunological and inflammatory components in age-related macular degeneration Mechanisms of age-related macular degeneration Animal models of age related macular degeneration Neurite Mistargeting and Inverse Order of Intraretinal Vascular Plexus Formation Precede Subretinal Vascularization in Vldlr Mutant Mice Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling RPE necroptosis in response to oxidative stress and in AMD Ex vivo dynamic imaging of retinal microglia using time-lapse confocal microscopy The mouse retina as an angiogenesis model.Age-related alterations in the dynamic behavior of microglia.Microglia in the mouse retina alter the structure and function of retinal pigmented epithelial cells: a potential cellular interaction relevant to AMD.Inflammatory choroidal neovascular membrane in posterior uveitis-pathogenesis and treatment.Platelet-derived growth factor (PDGF)-C inhibits neuroretinal apoptosis in a murine model of focal retinal degeneration.Association of complement factor H tyrosine 402 histidine genotype with posterior involvement in sarcoid-related uveitis.Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).Cigarette smoke-related hydroquinone dysregulates MCP-1, VEGF and PEDF expression in retinal pigment epithelium in vitro and in vivo.The effects of quercetin in cultured human RPE cells under oxidative stress and in Ccl2/Cx3cr1 double deficient mice.Enhanced HtrA2/Omi expression in oxidative injury to retinal pigment epithelial cells and murine models of neurodegeneration.Dysregulation in retinal para-inflammation and age-related retinal degeneration in CCL2 or CCR2 deficient mice.The Immune System and AMD Genetic basis of inherited macular dystrophies and implications for stem cell therapy.Implications of DNA leakage in eyes of mutant mice Role of fractalkine/CX3CR1 interaction in light-induced photoreceptor degeneration through regulating retinal microglial activation and migration Studying age-related macular degeneration using animal models.Peroxisome Proliferator-Activated Receptor Expression in Murine Models and Humans with Age-related Macular Degeneration.Single nucleotide polymorphisms in MCP-1 and its receptor are associated with the risk of age related macular degeneration.Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration.Age- and light-dependent development of localised retinal atrophy in CCL2(-/-)CX3CR1(GFP/GFP) mice.CX3CL1/CX3CR1 and CCL2/CCR2 chemokine/chemokine receptor complex in patients with AMD.Evidence for enhanced tissue factor expression in age-related macular degeneration.Differences in the distribution, phenotype and gene expression of subretinal microglia/macrophages in C57BL/6N (Crb1 rd8/rd8) versus C57BL6/J (Crb1 wt/wt) mice.Naloxone ameliorates retinal lesions in Ccl2/Cx3cr1 double-deficient mice via modulation of microglia.AAV5-mediated sFLT01 gene therapy arrests retinal lesions in Ccl2(-/-)/Cx3cr1(-/-) mice Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration.7-Ketocholesterol increases retinal microglial migration, activation, and angiogenicity: a potential pathogenic mechanism underlying age-related macular degeneration Progress and perspectives on the role of RPE cell inflammatory responses in the development of age-related macular degeneration.Cellular and 3D optical coherence tomography assessment during the initiation and progression of retinal degeneration in the Ccl2/Cx3cr1-deficient mouse.A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in mice

P2860

Q21284507-8705E2B9-4B2A-4328-8108-DFA371248F85 Q26768520-1034A386-D74D-4F50-BC62-0CD01C3B9D52 Q26823440-8A22FED3-17F7-4E91-9494-612A8C68A48A Q26849231-71B1939B-FB4F-4920-A9B7-ECC746891D54 Q27000182-07CF8231-F8A2-4419-8A6D-B826029155A1 Q27004686-715CF845-9302-49B9-B8C7-23705ECE3B1A Q27303147-3650ED41-8E58-407D-8CAD-3AC9373CF6C9 Q27304365-2CA98520-FC38-40D1-9E38-953F51F507D4 Q27693234-210BCF90-9D6F-43C3-8AFD-3EBA134F3D11 Q30486376-95D76879-F273-4A49-836F-A4F46C911629 Q30495106-3E35464E-68CD-47EB-91EF-26F2238ADA09 Q30498664-6AA6416E-6DB5-495B-B386-C85F6E990B6F Q30912692-7CD67EEA-B28D-44A9-A581-F87F61305E6E Q33520416-E520BB96-735A-420D-887F-4C366E1A6D23 Q33690414-12DA8BD4-3362-4B8B-9CD3-8E6BA7ABE9D1 Q33742322-486961AB-BD36-4265-B733-D55FA3F1833D Q33787737-EA8CC9B9-0D68-4FC5-B727-0E7EEB04CE0E Q33840832-2AFD8A65-28A0-4D16-AEB3-06ACBB380F7F Q33888950-3325626A-0FBC-4C05-8433-CA4896AD4010 Q33992324-2F35D267-0DB0-4A00-84A6-F95207108EF1 Q33995590-069E17C8-33BE-4F1A-BE35-003F2555FE46 Q34003743-5E59B4E5-C8B1-484C-A42D-8C791EDA842C Q34234455-9B135B69-927D-4289-997D-27197372F865 Q34243195-E048A6F3-2DBD-41FF-842E-9BD57928910B Q34247267-6AE52B26-A442-418C-8F56-71409304F62B Q34293850-AEDA01A1-110D-48AD-B28E-577F5DB8819D Q34386751-C06B048F-A8F2-46C0-8397-AD3B7635814A Q34490687-EDE4C8BB-026A-46C3-B2C0-5058C70888EB Q34508995-FA2D1348-1DF3-49C5-BF27-71E0C93A3ACD Q34700246-DDFAC677-F012-43AE-A989-C15E908B06FB Q34702581-BFEDEBF1-8B3F-423E-81D3-CE2DAFA7D129 Q34744314-DD6AF170-2BB1-4C74-BBA3-2D410E210274 Q35008752-C07B34A2-C4E1-4572-8359-A5EEAA4A4D0A Q35027458-1ED99CFD-2A24-43A9-BD75-59F996CA843C Q35106359-6C16D004-E518-4DC6-95B4-913B278964BA Q35159598-3C7ADC17-FBE6-402F-97B6-E67187BA0933 Q35179686-1626C6BB-031F-4145-984B-2D8FC33099D6 Q35557353-3430AAAF-C5C6-46F3-9B49-C117C28A09C1 Q35566342-23083C82-3EE3-41E0-8AC2-D391E7CE4237 Q35725801-8F65C581-BE69-441F-BDF1-9DF70B46666F

P2860

Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration.

http://www.wikidata.org/entity/Q36102995

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh

2007年學術文章

@zh-hant

name

Murine ccl2/cx3cr1 deficiency ...... -related macular degeneration.

@ast

Murine ccl2/cx3cr1 deficiency ...... -related macular degeneration.

@en

type

label

Murine ccl2/cx3cr1 deficiency ...... -related macular degeneration.

@ast

Murine ccl2/cx3cr1 deficiency ...... -related macular degeneration.

@en

prefLabel

Murine ccl2/cx3cr1 deficiency ...... -related macular degeneration.

@ast

Murine ccl2/cx3cr1 deficiency ...... -related macular degeneration.

@en

P1433

Q36102995-06762E2E-2E64-447B-85CE-27D78274D53E

P1476

Q36102995-1FE8FF3A-E013-485E-BAE6-35ADD55D680C

P2093

Q36102995-133A6861-E99D-496F-BA66-EC04297DB7E4

Q36102995-1AEB2AF9-4450-4865-B257-B90DD90A4A90

Q36102995-672F9226-B9D2-4F28-8705-99766CE4D941

Q36102995-6F0E2246-D9FE-4F4A-BF29-300B023873A5

Q36102995-900EA160-B410-4235-910D-C4CE7A0DB753

Q36102995-CE327ED4-4789-4C3E-B70D-C7036324A6B6

Q36102995-CEA52E75-7109-447F-B23E-82B5FA5E7FCF

Q36102995-D62A0D85-F98E-4CF9-B409-7DB265467037

Q36102995-E3763F54-7100-4286-846D-B8D5CA1A52D7

Q36102995-FA834BDD-A1E5-4AEA-B8F1-1CEB00CB2DF6

P2860

Q36102995-016F3D74-E7D7-4AB3-A394-0AAC5D906C9A

Q36102995-03852685-311A-4F01-8172-4375B9E714D9

Q36102995-078088EE-00AA-4BC8-8D36-D0173860C818

Q36102995-08088861-8E64-485E-8FED-F3824546AE01

Q36102995-0BAF2E97-CA00-49F0-9F45-533F17B591B5

Q36102995-18446E04-6137-47AC-9779-F5B903593D04

Q36102995-228E64D1-F2D1-4397-BA77-2DBD5BD7A333

Q36102995-243B5872-FD37-4972-BE6A-74A4106E1E15

Q36102995-25E30F42-2DAB-424F-9F8D-9042AEF8092A

Q36102995-265F335A-605D-4D72-8199-226EA0F9DA9E

P304

Q36102995-CC773679-AA36-436B-9D28-DAD83B271F0E

P31

Q36102995-2EC0ACC9-7A81-415F-A655-B693356A4BF9

P356

Q36102995-CC4309B8-20FB-4194-BDEF-D9051EC9EF52

P407

Q36102995-B0E3B13D-754B-456B-91D8-55E6269146CD

P433

Q36102995-55622B44-3204-44F1-9142-EBCBD234E7E2

P478

Q36102995-3F01A70F-6F48-46A7-A6A2-58F33DBA35D5

P50

Q36102995-2ABD6597-B5A1-441A-BB12-6E0E4591FD44

Q36102995-6059BD44-ABB1-4675-80EE-828DCE84920C

P577

Q36102995-78877E15-FCA9-4451-8559-619BBECF2F22

P5875

Q36102995-A66DDD26-A39E-45CB-87A9-E343922142BC

P698

Q36102995-0CDF4BE0-857E-4579-B8AC-D62FF7BD17C5

P932

Q36102995-157B787F-F2F1-4331-9333-2E7ABB46DA01

P356

P1433

Investigative Ophthalmology & Visual Science

P1476

Murine ccl2/cx3cr1 deficiency ...... e-related macular degeneration

@en

P2093

Christine M Bojanowski

http://www.w3.org/2001/XMLSchema#string

Chunyue Yin

http://www.w3.org/2001/XMLSchema#string

D Joshua Cameron

http://www.w3.org/2001/XMLSchema#string

Defen Shen

http://www.w3.org/2001/XMLSchema#string

Jeffrey A Kowalak

http://www.w3.org/2001/XMLSchema#string

Kang Zhang

http://www.w3.org/2001/XMLSchema#string

Kevin I Rosenberg

http://www.w3.org/2001/XMLSchema#string

Min Zhou

http://www.w3.org/2001/XMLSchema#string

Robert J Ross

http://www.w3.org/2001/XMLSchema#string

Zhengping Zhuang

http://www.w3.org/2001/XMLSchema#string

P2860

An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice

MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis

Drusen complement components C3a and C5a promote choroidal neovascularization

Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

Susceptibility genes for age-related maculopathy on chromosome 10q26.

Complement factor H polymorphism in age-related macular degeneration

CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor for coronary artery disease

Complement factor H variant increases the risk of age-related macular degeneration

P304

3827-3836

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1167/IOVS.07-0051

http://www.w3.org/2001/XMLSchema#string

P407

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

48

http://www.w3.org/2001/XMLSchema#string

P50

P577

2007-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6185554

http://www.w3.org/2001/XMLSchema#string

P698

17652758

http://www.w3.org/2001/XMLSchema#string

P932

2048751

http://www.w3.org/2001/XMLSchema#string