eIF4E is a central node of an RNA regulon that governs cellular proliferation. - Wikidata - wikimedia - TriplyDB

eIF4E is a central node of an RNA regulon that governs cellular proliferation.

eIF4E is a central node of an RNA regulon that governs cellular proliferation.

http://www.wikidata.org/entity/Q36119000

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The signal sequence coding region promotes nuclear export of mRNA The case for junk DNA PML nuclear bodies Tracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4E The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway.Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP The mRNA export factor Gle1 and inositol hexakisphosphate regulate distinct stages of translation 4E-BP3 regulates eIF4E-mediated nuclear mRNA export and interacts with replication protein A2 Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?Regulation of mRNA export by the PI3 kinase/AKT signal transduction pathway.Multiple Export Mechanisms for mRNAs Postage for the messenger: designating routes for nuclear mRNA export Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition HTLV-1 Rex Tunes the Cellular Environment Favorable for Viral Replication The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA Pondering the puzzle of PML (promyelocytic leukemia) nuclear bodies: can we fit the pieces together using an RNA regulon?Intestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells.A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery.Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence.eIF4F-like complexes formed by cap-binding homolog TbEIF4E5 with TbEIF4G1 or TbEIF4G2 are implicated in post-transcriptional regulation in Trypanosoma brucei Atomic basis of CRM1-cargo recognition, release and inhibition Pathophysiological roles of Pim-3 kinase in pancreatic cancer development and progression.Functional characterization of the HuR:CD83 mRNA interaction.The efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 compared with rapamycin in renal cell carcinoma.Trypanosoma brucei translation initiation factor homolog EIF4E6 forms a tripartite cytosolic complex with EIF4G5 and a capping enzyme homolog.Experimental approaches for the treatment of malignant gliomas.Impact of nuclear organization and dynamics on epigenetic regulation in the central nervous system: implications for neurological disease states.Phosphatidylinositol 3-kinase: the oncoprotein.Identification of two novel inhibitors of mTOR signaling pathway based on high content screening.Ribavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer.Structure-activity relationship study of 4EGI-1, small molecule eIF4E/eIF4G protein-protein interaction inhibitors.Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches.Gle1 is a multifunctional DEAD-box protein regulator that modulates Ded1 in translation initiation Ribosomal Biogenesis and Translational Flux Inhibition by the Selective Inhibitor of Nuclear Export (SINE) XPO1 Antagonist KPT-185.Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein.Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue.Dual PI3K/mTOR inhibitor NVP-BEZ235 suppresses hypoxia-inducible factor (HIF)-1α expression by blocking protein translation and increases cell death under hypoxia.The eIF4E RNA regulon promotes the Akt signaling pathway.

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P2860

eIF4E is a central node of an RNA regulon that governs cellular proliferation.

http://www.wikidata.org/entity/Q36119000

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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name

eIF4E is a central node of an RNA regulon that governs cellular proliferation.

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eIF4E is a central node of an RNA regulon that governs cellular proliferation.

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type

label

eIF4E is a central node of an RNA regulon that governs cellular proliferation.

@ast

eIF4E is a central node of an RNA regulon that governs cellular proliferation.

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prefLabel

eIF4E is a central node of an RNA regulon that governs cellular proliferation.

@ast

eIF4E is a central node of an RNA regulon that governs cellular proliferation.

@en

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P1433

Journal of Cell Biology

P1476

eIF4E is a central node of an RNA regulon that governs cellular proliferation.

@en

P2093

Biljana Culjkovic

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Katherine L B Borden

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Lucy Skrabanek

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Melisa Ruiz-Gutierrez

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P2860

PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth

Regulation of the selenoprotein SelS by glucose deprivation and endoplasmic reticulum stress - SelS is a novel glucose-regulated protein

A cap-binding protein complex mediating U snRNA export

The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling.

Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins.

Requirements for the nuclear export of the small ribosomal subunit.

tRNA nuclear export in saccharomyces cerevisiae: in situ hybridization analysis.

Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery.

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415-426

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10.1083/JCB.200607020

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3

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175

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Ivan Topisirovic

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2006-10-30T00:00:00Z

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6721377

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17074885

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2064519

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