Hepatic IGFBP1 is a prosurvival factor that binds to BAK, protects the liver from apoptosis, and antagonizes the proapoptotic actions of p53 at mitochondria
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Identification of metabolites, clinical chemistry markers and transcripts associated with hepatotoxicityHsp70 May Be a Molecular Regulator of Schistosome Host InvasionHepatic gene expression profiling of 5'-AMP-induced hypometabolism in miceInsulin-like growth factor binding protein-1 inhibits cancer cell invasion and is associated with poor prognosis in hepatocellular carcinoma.Mutation of IGFBP7 causes upregulation of BRAF/MEK/ERK pathway and familial retinal arterial macroaneurysmsNuclear export and mitochondrial and endoplasmic reticulum localization of IGF-binding protein 3 regulate its apoptotic properties.Global Igfbp1 deletion does not affect prostate cancer development in a c-Myc transgenic mouse modelMDM2-p53 pathway in hepatocellular carcinoma.Sustained antidiabetic effects of a berberine-containing Chinese herbal medicine through regulation of hepatic gene expression.Decline in circulating insulin-like growth factors and mortality in older adults: cardiovascular health study all-stars study.Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemiaGlioblastoma-derived Macrophage Colony-stimulating Factor (MCSF) Induces Microglial Release of Insulin-like Growth Factor-binding Protein 1 (IGFBP1) to Promote AngiogenesisInduction and contribution of beta platelet-derived growth factor signalling by hepatic stellate cells to liver regeneration after partial hepatectomy in mice.Direct regulation of IGF-binding protein 1 promoter by interleukin-1β via an insulin- and FoxO-1-independent mechanism.Maternal protein restriction regulates IGF2 system in placental labyrinth.Hypoxia and leucine deprivation induce human insulin-like growth factor binding protein-1 hyperphosphorylation and increase its biological activityThe p53 Codon 72 Polymorphism Modifies the Cellular Response to Inflammatory Challenge in the LiverThe mitochondrial p53 pathway.Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model.Transduction of fetal mice with a feline lentiviral vector induces liver tumors which exhibit an E2F activation signature.Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis-persistent pollutants affect programmed cell death.Multi-tasking: nuclear transcription factors with novel roles in the mitochondria.Effects of physical activity upon the liver.TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression.Inhibition of stress-inducible HSP70 impairs mitochondrial proteostasis and function.Comparative assessment of the apoptotic potential of silver nanoparticles synthesized by Bacillus tequilensis and Calocybe indica in MDA-MB-231 human breast cancer cells: targeting p53 for anticancer therapy.Mitochondrial death functions of p53.Epigonal conditioned media from bonnethead shark, Sphyrna tiburo, induces apoptosis in a T-cell leukemia cell line, Jurkat E6-1.Isatis indigotica induces hepatocellular cancer cell death via caspase-independent apoptosis-inducing factor translocation apoptotic pathway in vitro and in vivo.Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin.A small molecule inhibitor of inducible heat shock protein 70.The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells.Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication.Mitochondrial p53 Contributes to Reovirus-Induced Neuronal Apoptosis and Central Nervous System Injury in a Mouse Model of Viral Encephalitis.Milk disrupts p53 and DNMT1, the guardians of the genome: implications for acne vulgaris and prostate cancer.Etoposide induces cell death via mitochondrial-dependent actions of p53.Atopic dermatitis causes lipid accumulation in the liver of NC/Nga mouse.Involvement of the insulin-like growth factor binding proteins in the cancer cell response to DNA damage.Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms.The pathogenesis of diclofenac induced immunoallergic hepatitis in a canine model of liver injury.
P2860
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P2860
Hepatic IGFBP1 is a prosurvival factor that binds to BAK, protects the liver from apoptosis, and antagonizes the proapoptotic actions of p53 at mitochondria
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Hepatic IGFBP1 is a prosurviva ...... actions of p53 at mitochondria
@ast
Hepatic IGFBP1 is a prosurviva ...... actions of p53 at mitochondria
@en
type
label
Hepatic IGFBP1 is a prosurviva ...... actions of p53 at mitochondria
@ast
Hepatic IGFBP1 is a prosurviva ...... actions of p53 at mitochondria
@en
prefLabel
Hepatic IGFBP1 is a prosurviva ...... actions of p53 at mitochondria
@ast
Hepatic IGFBP1 is a prosurviva ...... actions of p53 at mitochondria
@en
P2860
P356
P1433
P1476
Hepatic IGFBP1 is a prosurviva ...... actions of p53 at mitochondria
@en
P2093
Donna L George
J I-Ju Leu
P2860
P304
P356
10.1101/GAD.1567107
P577
2007-12-01T00:00:00Z