A small molecule inhibitor of inducible heat shock protein 70.
about
Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with peptide substrateA comprehensive glossary of autophagy-related molecules and processes (2nd edition)A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugateProteomic identification of Hsp70 as a new Plk1 substrate in arsenic trioxide-induced mitotically arrested cellsContribution of the Type II Chaperonin, TRiC/CCT, to OncogenesisHSP90 and HSP70: Implication in Inflammation Processes and Therapeutic Approaches for Myeloproliferative NeoplasmsFeatures of protein-protein interactions that translate into potent inhibitors: topology, surface area and affinityHsp70 May Be a Molecular Regulator of Schistosome Host InvasionFunctional analysis of Hsp70 inhibitorsThe human HSP70 family of chaperones: where do we stand?Drugging the addict: non-oncogene addiction as a target for cancer therapyStructural basis for the inhibition of HSP70 and DnaK chaperones by small-molecule targeting of a C-terminal allosteric pocketSelective targeting of the stress chaperome as a therapeutic strategySuppression of expression of heat shock protein 70 by gefitinib and its contribution to pulmonary fibrosisRhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistanceDrug resistance in natural isolates of Leishmania donovani s.l. promastigotes is dependent of Pgp170 expressionInhibition of inducible heat shock protein-70 (hsp72) enhances bortezomib-induced cell death in human bladder cancer cellsThe master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infectionInvestigating Apoptozole as a Chemical Probe for HSP70 InhibitionHSP70 regulates the function of mitotic centrosomesHsp70-Bag3 interactions regulate cancer-related signaling networksA novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxinHSPA8/HSC70 chaperone protein: structure, function, and chemical targeting.A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.Lysosomal rerouting of Hsp70 trafficking as a potential immune activating tool for targeting melanoma.A modified HSP70 inhibitor shows broad activity as an anticancer agent.A phase I study of PF-04929113 (SNX-5422), an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumor malignancies and lymphomas.Inhibition of Mitochondrial p53 Accumulation by PFT-μ Prevents Cisplatin-Induced Peripheral Neuropathy.A novel mechanism linking memory stem cells with innate immunity in protection against HIV-1 infectionp53 and mitochondrial function in neurons.Evaluating melanoma drug response and therapeutic escape with quantitative proteomicsInhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradationp53 and ARF: unexpected players in autophagy.Heat shock protein 70 (hsp70) as an emerging drug target.Protein chaperones: a composition of matter review (2008 - 2013).Synergetic cytotoxic activity toward breast cancer cells enhanced by the combination of Antp-TPR hybrid peptide targeting Hsp90 and Hsp70-targeted peptide.Elevation in body temperature to fever range enhances and prolongs subsequent responsiveness of macrophages to endotoxin challengeAutophagy-regulating small molecules and their therapeutic applications.Protein folding in the cytoplasm and the heat shock response.p97-containing complexes in proliferation control and cancer: emerging culprits or guilt by association?
P2860
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P2860
A small molecule inhibitor of inducible heat shock protein 70.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
A small molecule inhibitor of inducible heat shock protein 70.
@en
A small molecule inhibitor of inducible heat shock protein 70.
@nl
type
label
A small molecule inhibitor of inducible heat shock protein 70.
@en
A small molecule inhibitor of inducible heat shock protein 70.
@nl
prefLabel
A small molecule inhibitor of inducible heat shock protein 70.
@en
A small molecule inhibitor of inducible heat shock protein 70.
@nl
P2093
P2860
P1433
P1476
A small molecule inhibitor of inducible heat shock protein 70.
@en
P2093
Amanda Frank
Donna L George
J I-Ju Leu
Julia Pimkina
Maureen E Murphy
P2860
P356
10.1016/J.MOLCEL.2009.09.023
P577
2009-10-01T00:00:00Z