Chronic myeloid leukaemia: stem cell derived but progenitor cell driven.
about
Targeting RAD51 phosphotyrosine-315 to prevent unfaithful recombination repair in BCR-ABL1 leukemia.BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability.Subcellular distribution of p210(BCR-ABL) in CML cell lines and primary CD34+ CML cells.Hematopoiesis and its disorders: a systems biology approachFTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia.Gene expression profile of circulating CD34(+) cells and granulocytes in chronic myeloid leukemiaWhy do chronic myelogenous leukemia stem cells survive allogeneic stem cell transplantation or imatinib: does it really matter?Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche?Sphingomyelin synthase 1 activity is regulated by the BCR-ABL oncogeneNormal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases.BCR/ABL, DNA damage and DNA repair: implications for new treatment concepts.Chronic myeloid leukemia cells refractory/resistant to tyrosine kinase inhibitors are genetically unstable and may cause relapse and malignant progression to the terminal disease state.BCR-ABL1 kinase: hunting an elusive target with new weaponsBCR/ABL stimulates WRN to promote survival and genomic instability.Tyrosine kinase inhibitor therapy can cure chronic myeloid leukemia without hitting leukemic stem cells.AKT-induced reactive oxygen species generate imatinib-resistant clones emerging from chronic myeloid leukemia progenitor cells.Evolutionary dynamics of chronic myeloid leukemia.On the dynamics of neutral mutations in a mathematical model for a homogeneous stem cell population.Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway.Abnormal centrosome-centriole cycle in chronic myeloid leukaemia?Global gene expression profiles of hematopoietic stem and progenitor cells from patients with chronic myeloid leukemia: the effect of in vitro culture with or without imatinib.Community-acquired infections and their association with myeloid malignancies.Molecular signature of CD34(+) hematopoietic stem and progenitor cells of patients with CML in chronic phase.Antibody arrays identify protein-protein interactions in chronic myeloid leukaemia.Influence of PI-3K/Akt pathway on Wnt signalling in regulating myeloid progenitor cell proliferation. Evidence for a role of autocrine/paracrine Wnt regulation.
P2860
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P2860
Chronic myeloid leukaemia: stem cell derived but progenitor cell driven.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Chronic myeloid leukaemia: stem cell derived but progenitor cell driven.
@ast
Chronic myeloid leukaemia: stem cell derived but progenitor cell driven.
@en
type
label
Chronic myeloid leukaemia: stem cell derived but progenitor cell driven.
@ast
Chronic myeloid leukaemia: stem cell derived but progenitor cell driven.
@en
prefLabel
Chronic myeloid leukaemia: stem cell derived but progenitor cell driven.
@ast
Chronic myeloid leukaemia: stem cell derived but progenitor cell driven.
@en
P356
P1433
P1476
Chronic myeloid leukaemia: stem cell derived but progenitor cell driven.
@en
P2093
Myrtle Y Gordon
Stephen B Marley
P356
10.1042/CS20040336
P407
P577
2005-07-01T00:00:00Z