CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment.
about
Wnt signaling networks in autism spectrum disorder and intellectual disabilityTranscriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stressChd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signalingApplications of CRISPR technologies in research and beyond.Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletionTranscriptomics analysis of iPSC-derived neurons and modeling of neuropsychiatric disorders.A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular ResearchCRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells.Recent Advances in CRISPR-Cas9 Genome Editing Technology for Biological and Biomedical Investigations.Generation of improved human cerebral organoids from single copy DYRK1A knockout induced pluripotent stem cells in trisomy 21: hypothetical solutions for neurodevelopmental models and therapeutic alternatives in down syndrome.Modeling the autistic cell: iPSCs recapitulate developmental principles of syndromic and nonsyndromic ASD.Using Induced Pluripotent Stem Cells to Investigate Complex Genetic Psychiatric Disorders.Autism genetics - an overview.CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.Human induced pluripotent stem cells for modelling neurodevelopmental disorders.Transcribing the connectome: roles for transcription factors and chromatin regulators in activity-dependent synapse development.Application of CRISPR/Cas9 to the study of brain development and neuropsychiatric disease.A Rapid Pipeline to Model Rare Neurodevelopmental Disorders with Simultaneous CRISPR/Cas9 Gene Editing.Toward a conceptual framework for early brain and behavior development in autism.A Scaled Framework for CRISPR Editing of Human Pluripotent Stem Cells to Study Psychiatric Disease.RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome.Characteristics of allelic gene expression in human brain cells from single-cell RNA-seq data analysis.Understanding neurodevelopmental disorders using human pluripotent stem cell-derived neurons.Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons.Translating genetic and preclinical findings into autism therapies.Genome-editing applications of CRISPR-Cas9 to promote in vitro studies of Alzheimer's disease.Development and disease in a dish: the epigenetics of neurodevelopmental disorders.Modeling Neuropsychiatric and Neurodegenerative Diseases With Induced Pluripotent Stem Cells.Uncovering True Cellular Phenotypes: Using Induced Pluripotent Stem Cell-Derived Neurons to Study Early Insults in Neurodevelopmental Disorders.Convergent Pathways in Idiopathic Autism Revealed by Time Course Transcriptomic Analysis of Patient-Derived Neurons.Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells
P2860
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P2860
CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
CRISPR/Cas9-mediated heterozyg ...... networks in neurodevelopment.
@ast
CRISPR/Cas9-mediated heterozyg ...... networks in neurodevelopment.
@en
type
label
CRISPR/Cas9-mediated heterozyg ...... networks in neurodevelopment.
@ast
CRISPR/Cas9-mediated heterozyg ...... networks in neurodevelopment.
@en
prefLabel
CRISPR/Cas9-mediated heterozyg ...... networks in neurodevelopment.
@ast
CRISPR/Cas9-mediated heterozyg ...... networks in neurodevelopment.
@en
P2093
P2860
P921
P1433
P1476
CRISPR/Cas9-mediated heterozyg ...... networks in neurodevelopment.
@en
P2093
Anastasia Hrabovsky
Erika Pedrosa
Herbert M Lachman
Mingyan Lin
Wenjun Guo
Zheng Zhang
P2860
P2888
P356
10.1186/S13229-015-0048-6
P50
P577
2015-10-19T00:00:00Z
P5875
P6179
1037854172