about
Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humansEvaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytesAlterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various agesRiboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin CCharacterizing Benzo[a]pyrene-induced lacZ mutation spectrum in transgenic mice using next-generation sequencing.Evaluating genotoxicity data to identify a mode of action and its application in estimating cancer risk at low doses: A case study involving carbon tetrachloride.Can carcinogenic potency be predicted from in vivo genotoxicity data?: a meta-analysis of historical data.Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing.3-Methylcholanthrene (3-MC) and 4-chlorobiphenyl (PCB3) genotoxicity is gender-related in Fischer 344 transgenic rats.Characterisation of Muta™Mouse λgt10-lacZ transgene: evidence for in vivo rearrangements.Mutagenicity of furan in female Big Blue B6C3F1 miceAge-dependent accumulation of recombinant cells in the mouse pancreas revealed by in situ fluorescence imaging.A random mutation capture assay to detect genomic point mutations in mouse tissueChromium in drinking water: sources, metabolism, and cancer risksSimultaneous measurement of benzo[a]pyrene-induced Pig-a and lacZ mutations, micronuclei and DNA adducts in Muta™ Mouse.MutAIT: an online genetic toxicology data portal and analysis tools.Comet assay evaluation of six chemicals of known genotoxic potential in rats.Mutagenicity of ultraviolet A radiation in the lacI transgene in Big Blue mouse embryonic fibroblastsAssessing human germ-cell mutagenesis in the Postgenome Era: a celebration of the legacy of William Lawson (Bill) Russell.Efficient monitoring of in vivo pig-a gene mutation and chromosomal damage: summary of 7 published studies and results from 11 new reference compounds.Transgenic rodent assay for quantifying male germ cell mutant frequency.Significance of CpG methylation for solar UV-induced mutagenesis and carcinogenesis in skin.Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol.Hepatic mRNA, microRNA, and miR-34a-target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutationApplication of genomics in preclinical drug safety evaluation.Integrated one- and two-photon imaging platform reveals clonal expansion as a major driver of mutation load.S-nitrosoglutathione reductase deficiency increases mutagenesis from alkylation in mouse liverPostulated carbon tetrachloride mode of action: a review.Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents.Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta miceAn evaluation of the mode of action framework for mutagenic carcinogens case study: Cyclophosphamide.Oral exposure to commercially available coal tar-based pavement sealcoat induces murine genetic damage and mutations.Effects of 1,4-phenylenebis(methylene)selenocyanate on mutagenesis and p53 protein expression in the tongue of lacI rats treated with 4-nitroquinoline-N-oxide.Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cellsIn vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure.Mitochondrial DNA exhibits resistance to induced point and deletion mutations.Mutational spectra of human cancer.In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice.Evaluation of in vivo mutagenesis for assessing the health risk of air pollutants.A strategy to study genotoxicity: application to aquatic toxins, limits and solutions.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Detailed review of transgenic rodent mutation assays.
@ast
Detailed review of transgenic rodent mutation assays.
@en
type
label
Detailed review of transgenic rodent mutation assays.
@ast
Detailed review of transgenic rodent mutation assays.
@en
prefLabel
Detailed review of transgenic rodent mutation assays.
@ast
Detailed review of transgenic rodent mutation assays.
@en
P2093
P1433
P1476
Detailed review of transgenic rodent mutation assays.
@en
P2093
George R Douglas
Iain B Lambert
Sherri E Boucher
Timothy M Singer
P356
10.1016/J.MRREV.2005.04.002
P407
P577
2005-09-01T00:00:00Z