Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation.
about
STATs: An Old Story, Yet MesmerizingSOCS3: An essential physiological inhibitor of signaling by interleukin-6 and G-CSF family cytokinesThe biology and mechanism of action of suppressor of cytokine signaling 3SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibitionPwp1 is required for the differentiation potential of mouse embryonic stem cells through regulating Stat3 signalingSOCS1 and SOCS3 in the control of CNS immunitySuppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways.SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor.A critical role for SHP2 in STAT5 activation and growth factor-mediated proliferation, survival, and differentiation of human CD34+ cells.Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signalingThe JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma.Suppressor of cytokine signaling 3 inhibits breast tumor kinase activation of STAT3.A requirement for SOCS-1 and SOCS-3 phosphorylation in Bcr-Abl-induced tumorigenesis.Regulation of multiple cytokine signalling pathways by SOCS3 is independent of SOCS2.Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factorSuppression of cytokine signaling: the SOCS perspective.Muscle-specific deletion of SOCS3 increases the early inflammatory response but does not affect regeneration after myotoxic injuryJAK-STAT3 and somatic cell reprogramming.The Role of the Leukemia Inhibitory Factor (LIF) - Pathway in Derivation and Maintenance of Murine Pluripotent Stem Cells.Inhibition of IL-6 family cytokines by SOCS3.Erythropoietin receptor response circuitsUnbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3.Leukemia inhibitory factor: a paracrine mediator of bone metabolism.The SOCS box-adapting proteins for ubiquitination and proteasomal degradation.Role of Ubiquitylation in Controlling Suppressor of Cytokine Signalling 3 (SOCS3) Function and Expression.Kinase inhibition, competitive binding and proteasomal degradation: resolving the molecular function of the suppressor of cytokine signaling (SOCS) proteins.LIF signal in mouse embryonic stem cells.SOCS3 expression correlates with severity of inflammation in mouse hepatitis virus strain 3-induced acute liver failure and HBV-ACLF.CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.
P2860
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P2860
Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT phosphorylation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Deletion of the SOCS box of su ...... but not STAT phosphorylation.
@ast
Deletion of the SOCS box of su ...... but not STAT phosphorylation.
@en
type
label
Deletion of the SOCS box of su ...... but not STAT phosphorylation.
@ast
Deletion of the SOCS box of su ...... but not STAT phosphorylation.
@en
prefLabel
Deletion of the SOCS box of su ...... but not STAT phosphorylation.
@ast
Deletion of the SOCS box of su ...... but not STAT phosphorylation.
@en
P2093
P2860
P1433
P1476
Deletion of the SOCS box of su ...... but not STAT phosphorylation.
@en
P2093
Edward J McManus
Evelyn Trounson
Jeffery J Babon
Jian-Guo Zhang
Kristy Boyle
Lorraine Robb
Sandra E Nicholson
P2860
P304
P356
10.1016/J.CELLSIG.2008.11.002
P577
2008-11-12T00:00:00Z