Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection.
about
HIV therapeutic vaccines: moving towards a functional cureADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challengeA vaccine encoding conserved promiscuous HIV CD4 epitopes induces broad T cell responses in mice transgenic to multiple common HLA class II moleculesImmunization with single-cycle SIV significantly reduces viral loads after an intravenous challenge with SIV(mac)239.In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4 T cells in acute HIV-1 infection.Multi-low-dose mucosal simian immunodeficiency virus SIVmac239 challenge of cynomolgus macaques immunized with "hyperattenuated" SIV constructs.Macaques vaccinated with simian immunodeficiency virus SIVmac239Delta nef delay acquisition and control replication after repeated low-dose heterologous SIV challenge.Broad and cross-clade CD4+ T-cell responses elicited by a DNA vaccine encoding highly conserved and promiscuous HIV-1 M-group consensus peptides.Novel vaccine vectors for HIV-1.Vaccination with live attenuated simian immunodeficiency virus causes dynamic changes in intestinal CD4+CCR5+ T cells.Regulation of SIV antigen-specific CD4+ T cellular immunity via autophagosome-mediated MHC II molecule-targeting antigen presentation in mice.Vaccine protection against simian immunodeficiency virus in monkeys using recombinant gamma-2 herpesvirus.HIV-DNA Given with or without Intradermal Electroporation Is Safe and Highly Immunogenic in Healthy Swedish HIV-1 DNA/MVA Vaccinees: A Phase I Randomized Trial.Lessons in nonhuman primate models for AIDS vaccine research: from minefields to milestones.New paradigms for HIV/AIDS vaccine development.Protective attenuated lentivirus immunization induces SIV-specific T cells in the genital tract of rhesus monkeys.Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV InfectionDynamics of T-cell responses and memory T cells during primary simian immunodeficiency virus infection in cynomolgus macaques.Preserved central memory and activated effector memory CD4+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study.The major histocompatibility complex class II alleles Mamu-DRB1*1003 and -DRB1*0306 are enriched in a cohort of simian immunodeficiency virus-infected rhesus macaque elite controllersVaccination of rhesus macaques with a vif-deleted simian immunodeficiency virus proviral DNA vaccine.Macaques vaccinated with live-attenuated SIV control replication of heterologous virus.Influence of mismatch of Env sequences on vaccine protection by live attenuated simian immunodeficiency virus.Conditionally-live attenuated SIV upregulates global T effector memory cell frequency under replication permissive conditionsAcute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus.Polyfunctional CD4+ T-cell induction in neutralizing antibody-triggered control of simian immunodeficiency virus infection.Gag- and Nef-specific CD4+ T cells recognize and inhibit SIV replication in infected macrophages early after infection.Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8(+) T cells independent of IFN-gamma and CD107a responsesEffector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge.Mucosal immunization in macaques upregulates the innate APOBEC 3G anti-viral factor in CD4(+) memory T cells.Cellular and molecular mechanisms of memory T-cell survival.Flow cytometry based identification of simian immunodeficiency virus Env-specific B lymphocytes.High content cellular immune profiling reveals differences between rhesus monkeys and men.Vaccination with SIVmac239Deltanef activates CD4+ T cells in the absence of CD4 T-cell loss.HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome.Protection of macaques against AIDS with a live attenuated SHIV vaccine is of finite duration.The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques.
P2860
Q27002180-DBE2A505-EF3D-4E7D-9FCB-1A592BE66FD9Q27342615-81EAC309-3168-4194-95FB-8B6AB2D7E741Q28751663-665EAD3C-7839-43D3-A5C5-9C494938CB48Q33402455-3BAA0F90-A7A4-4937-B22B-FA53DDEADFC0Q33402486-CC31E282-FC85-4C6F-842F-CBB50627E1D4Q33648905-85A65433-68D3-47EF-B796-9C896AB9B1B5Q34120102-868BA31B-4DBC-461D-BE66-81D2FE47B5F3Q34428561-4C309CA8-3BBD-465E-B5C0-4E8DC03B9C73Q34541191-8BC90242-97BF-4E34-8ABC-FE3881283577Q34573745-1160FBC4-9B6E-4A71-A460-08F111E21A98Q35132375-EFBA331A-EE0E-4014-AE14-632075B699B6Q35531553-54EE13F6-668F-44E9-8A94-0D622BD28C46Q35677513-ABF43676-3091-4E76-95BA-BDF753AEA25BQ36009232-AE1F1C9A-2B62-4BC9-AEAD-5B30DF01A630Q36011269-273FF273-5752-4794-90C0-8643489CBC49Q36105923-665FB56B-65A4-4623-9C65-9CDF578EECDCQ36222317-CB2CE254-0BCC-4463-B3FD-AF35943652CCQ36315175-3F6E300D-0560-4D5E-9CD4-4760C0D8A952Q36315197-92CD4CB5-07BB-47B2-BCBC-AD596D33A1D7Q36424504-C837C9A2-194C-4318-B8E0-D00D807C09D2Q36846517-7DBEE818-BBF7-44E5-95FC-1A538D69557DQ36946545-AD050071-6339-4264-BA3B-946FF87AF58BQ36978847-389EB53A-A7A7-43A8-8A1B-E38E47A6968AQ36996766-D2BD3C32-29B4-43DC-AB8A-244FAFF9168BQ37123354-147BBF44-8D8E-4015-9016-57E3F870E8ABQ37191948-CE3DBB2E-5FEB-48FE-B820-1371034395DBQ37206430-3C8C1202-52AE-4257-871B-22309039FF64Q37276902-2CC53302-F483-4223-AC2C-67AE45C3A9D9Q37287080-BFFDB635-365D-490E-8335-8FF049AE764DQ37347854-57629F89-49F6-4284-9312-AB396B0ED7ECQ37403487-143524BB-2BB0-42DB-82AC-87862AAC9380Q39521335-0EC410C1-04A9-41DA-8F6F-9C8BDB69C73BQ39873561-6846D8DD-CB76-4434-B729-17A39DF81891Q41816425-BD434062-0C15-4770-ABA6-56449E6CC200Q41937295-90F65984-DF42-4025-A340-C93A6609A233Q42122289-4B0DECDF-2F51-4E2A-8207-370C3C8F8FA1Q54253587-CB8AF19E-5B55-46BE-A8AA-C2E0F390B526
P2860
Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Induction of a virus-specific ...... e by attenuated SIV infection.
@ast
Induction of a virus-specific ...... e by attenuated SIV infection.
@en
type
label
Induction of a virus-specific ...... e by attenuated SIV infection.
@ast
Induction of a virus-specific ...... e by attenuated SIV infection.
@en
prefLabel
Induction of a virus-specific ...... e by attenuated SIV infection.
@ast
Induction of a virus-specific ...... e by attenuated SIV infection.
@en
P2093
P2860
P356
P1476
Induction of a virus-specific ...... e by attenuated SIV infection.
@en
P2093
Amy Barabasz
Angela Carville
Jeffrey D Lifson
Marie-Claire Gauduin
Mike Piatak
R Paul Johnson
Ronald C Desrosiers
P2860
P304
P356
10.1084/JEM.20060134
P407
P577
2006-11-20T00:00:00Z