In vivo and in vitro clonal deletion of double-positive thymocytes.
about
Elimination of self-reactive T cells in the thymus: a timeline for negative selectionStructural Basis of Cytochrome c Presentation by IE kPositive selection in the thymus: an enigma wrapped in a mystery.Presenilins regulate alphabeta T cell development by modulating TCR signalingThe timing of TCR alpha expression critically influences T cell development and selectionHematopoietic lineage cell-specific protein 1 is recruited to the immunological synapse by IL-2-inducible T cell kinase and regulates phospholipase Cgamma1 Microcluster dynamics during T cell spreadingAffinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expressionFoxo transcription factors control regulatory T cell development and functionMechanisms and consequences of peptide selection by the I-Ak class II molecule.T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: the molecular basis of negative selection.Clonal deletion of specific thymocytes by an immunoglobulin idiotype.Negative selection of thymocytes expressing the D10 TCRKinase suppressor of Ras 1 is required for full ERK activation in thymocytes but not for thymocyte selection.Cyclosporin A blocks apoptosis by inhibiting the DNA binding activity of the transcription factor Nur77.Altered positive selection due to corecognition of floppy peptide/MHC II conformers supports an integrative model of thymic selection.Defective selection of thymic regulatory T cells accompanies autoimmunity and pulmonary infiltrates in Tcra-deficient mice double transgenic for human La/Sjögren's syndrome-B and human La-specific TCRNegative selection of CD4+ CD8+ thymocytes by T-cell receptor peptide antagonists.Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold.Natural regulatory T cells and self-tolerance.Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate diseasePeptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signalingPeripheral T cell activation and deletion induced by transfer of lymphocyte subsets expressing endogenous or exogenous mouse mammary tumor virus.Immature thymocytes become sensitive to calcium-mediated apoptosis with the onset of CD8, CD4, and the T cell receptor expression: a role for bcl-2?An essential role for gp39, the ligand for CD40, in thymic selection.Positive selection is not required for thymic maturation of transgenic gamma delta T cells.The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasisInduction of the early growth response (Egr) family of transcription factors during thymic selection.TCR and Notch signaling in CD4 and CD8 T-cell development.Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cellsFunctional redundancy between thymic CD8α+ and Sirpα+ conventional dendritic cells in presentation of blood-derived lysozyme by MHC class II proteins.Disruption of the CD4-major histocompatibility complex class II interaction blocks the development of CD4(+) T cells in vivoRegulation of the Nur77 orphan steroid receptor in activation-induced apoptosisRegulation of AP-1 and NFAT transcription factors during thymic selection of T cells.Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB.Inhibition of intrathymic T cell development by expression of a transgenic antagonist peptide.Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis.Egr2 is required for Bcl-2 induction during positive selection.Differential role of the transcription factor NF-kappaB in selection and survival of CD4+ and CD8+ thymocytes.Autoreactive thymic B cells are efficient antigen-presenting cells of cognate self-antigens for T cell negative selection.Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire
P2860
Q27317399-1EFFDA01-3D89-4A11-97E4-E3B1EE72BDD9Q27638866-2550BAAA-6E45-42C2-BD7F-5B1EEB0E2863Q27690789-244194CE-E38F-4A1D-B263-EDD7E476EED1Q28587555-42467291-7A66-4041-A3D2-3C6AFFCCFE45Q30443379-7B3162CC-B859-41AA-9119-B587EC9ED857Q30541593-6C0BE30E-9B5B-4001-A55D-DC1D92BCA279Q33639952-DD6476A5-5A2F-489C-8606-362450D2EF56Q33774905-8B5DA132-25DA-4247-9F3C-E16E4977E4E7Q33815430-FA39ADB2-B3B7-4F90-9BA0-752892DECD89Q33886507-768A8277-3DA5-4F27-B220-EA8B294B9701Q34042176-487FE94C-ABE0-4068-ABD7-F34D4B557AB3Q34067924-DAD5B37F-E5FD-4133-9CAE-F81337F9D8AAQ34293064-D7E8E8F0-1D72-47AC-9FEC-2C911377A9BFQ34766627-1369E22C-7432-4A66-BF7C-232512DC8A77Q34982958-EE45F70E-9F29-4A56-B494-59D747A9E0E9Q35070028-960FC553-51CE-4BD6-9352-0F5EEAC3DF76Q35213326-81173E7C-5284-4EBB-ACFF-DFB363013CF2Q35982959-6E7C6891-8294-4281-B99F-678731F47FD1Q36078038-4AC35A88-9C32-4764-A04D-143795FEA8BDQ36284342-9575E86A-C0DB-4DC2-8D05-AF131E6247ABQ36361605-4580432A-77FE-46C2-830F-2333A633A56AQ36361753-68342D03-8BEE-4E5B-8E78-9967E997AAC6Q36362522-E10109A1-443A-4AE3-AC37-6184A9606837Q36365446-D37F5BAC-BD57-4807-9850-6FE6803E414BQ36366715-A42098C4-7D60-4F6B-998A-0DD4B15EE5BCQ36376720-F1993DAB-7D9B-438F-8753-26C56593365EQ36376794-BECC9785-F8C2-4041-A575-113803EF8995Q36382785-34C4DAEB-27B4-4FB8-B1C9-6C2E99842D5AQ36401236-88089EAC-DC6F-4B07-9373-42C1146362AEQ36433047-ED57BA9A-E00E-4F1D-B52E-426E1F7E6939Q36475513-B45AF8AE-30A2-4873-BBC9-0B57F0C5720BQ36555939-B04E1694-E5F4-4F4A-9094-E518C212FE8BQ36557490-E43AD1A0-6E16-4CE7-A9E1-81BD1AEEA825Q36603522-468A83C9-7A2B-48E7-98B7-14AC8F1F3091Q36734207-D88BBB1A-A6B2-4046-ACC3-C83D2666C334Q36793951-48BEB3C0-0517-4526-B52A-91BC2D6568ACQ36982963-8245487C-ED3B-4310-816B-75A5211C699BQ37161842-41AE4E23-AE1E-49E8-AA19-A9D32E605971Q37240479-EAF4C38E-1500-4286-BBF3-F9715E86BD7BQ37256881-A35A2171-6623-4894-B2F8-E4CB82DB5F03
P2860
In vivo and in vitro clonal deletion of double-positive thymocytes.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
In vivo and in vitro clonal deletion of double-positive thymocytes.
@ast
In vivo and in vitro clonal deletion of double-positive thymocytes.
@en
type
label
In vivo and in vitro clonal deletion of double-positive thymocytes.
@ast
In vivo and in vitro clonal deletion of double-positive thymocytes.
@en
prefLabel
In vivo and in vitro clonal deletion of double-positive thymocytes.
@ast
In vivo and in vitro clonal deletion of double-positive thymocytes.
@en
P2093
P2860
P356
P1476
In vivo and in vitro clonal deletion of double-positive thymocytes.
@en
P2093
P2860
P304
P356
10.1084/JEM.175.5.1307
P407
P577
1992-05-01T00:00:00Z