Disruption of the CD4-major histocompatibility complex class II interaction blocks the development of CD4(+) T cells in vivo
about
An MHC class II restriction bias in CD4 T cell responses toward I-A is altered to I-E in DM-deficient miceRestricted autoantigen recognition associated with deletional and adaptive regulatory mechanisms.Coevolution of TCR-MHC interactions: conserved MHC tertiary structure is not sufficient for interactions with the TCR.Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptideCognate stimulatory B-cell-T-cell interactions are critical for T-cell help recruited by glycoconjugate vaccines.CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation.T-cell development and the CD4-CD8 lineage decision.The activation threshold of CD4+ T cells is defined by TCR/peptide-MHC class II interactions in the thymic medullaAn antagonist peptide mediates positive selection and CD4 lineage commitment of MHC class II-restricted T cells in the absence of CD4Restricted MHC-peptide repertoire predisposes to autoimmunity.The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes.The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate.Influence of CD4 T cells and the source of major histocompatibility complex class II-restricted peptides on cytotoxic T-cell priming by dendritic cells
P2860
Q27469164-2C836656-D9B2-40B0-A4F4-AA9B6076938AQ30492902-47129275-4F8B-46F7-9B67-65AC33EFF9A2Q33780788-4328B022-834F-48C9-B4BB-18384E9AADE4Q33930556-70EB5F07-007A-4CE7-A9C2-1BD99C71306BQ34002718-24CDC228-888E-4301-8E88-281BDBB79DF3Q34501441-0AA14CAF-DA0D-4996-B224-BF9B418077F5Q34659128-D2C0C086-BA33-41F8-91F7-DEBEAC3C4C88Q34812722-1B8DBFBE-F86A-4C1D-B35E-A641FDCC66EEQ36402496-C965C8BD-CCD9-474B-BE41-D035B08D764EQ36402958-24D50AF1-7B43-4FC0-9220-96F57172005FQ46647653-EAF61CC0-95E1-480A-99A3-0BC024EA29F4Q51081581-1AA96956-2631-48CC-8927-463381559AE3Q56967605-62020110-4285-434A-AAAF-7AB24EF707AE
P2860
Disruption of the CD4-major histocompatibility complex class II interaction blocks the development of CD4(+) T cells in vivo
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Disruption of the CD4-major hi ...... ment of CD4(+) T cells in vivo
@ast
Disruption of the CD4-major hi ...... ment of CD4(+) T cells in vivo
@en
type
label
Disruption of the CD4-major hi ...... ment of CD4(+) T cells in vivo
@ast
Disruption of the CD4-major hi ...... ment of CD4(+) T cells in vivo
@en
prefLabel
Disruption of the CD4-major hi ...... ment of CD4(+) T cells in vivo
@ast
Disruption of the CD4-major hi ...... ment of CD4(+) T cells in vivo
@en
P2093
P2860
P356
P1476
Disruption of the CD4-major hi ...... ment of CD4(+) T cells in vivo
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.8.4493
P407
P577
1998-04-01T00:00:00Z