STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease. - Wikidata - wikimedia - TriplyDB

STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease.

STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease.

http://www.wikidata.org/entity/Q36231545

about

Therapeutics for Graft-versus-Host Disease: From Conventional Therapies to Novel Virotherapeutic Strategies Disrupted regulatory T cell homeostasis in inflammatory bowel diseases Treg functional stability and its responsiveness to the microenvironment NAD(+) regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4(+) CD25(+) Foxp3(+) T cells independent.Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease.The Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical Overview Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases Rapamycin resistant murine th9 cells have a stable in vivo phenotype and inhibit graft-versus-host reactivity.A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3.Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10 Interleukin-6 in Allogeneic Stem Cell Transplantation: Its Possible Importance for Immunoregulation and As a Therapeutic Target.Ubiquitous points of control over regulatory T cells.MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation.SOCS1 and regulation of regulatory T cells plasticity.Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.Transcriptional and epigenetic regulation of T-helper lineage specification.Lineage stability and phenotypic plasticity of Foxp3⁺ regulatory T cells.Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo.CD4+ T cell STAT3 phosphorylation precedes acute GVHD, and subsequent Th17 tissue invasion correlates with GVHD severity and therapeutic response.The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.Leptin receptor signaling in T cells is required for Th17 differentiation.Advances in understanding the pathogenesis of graft-versus-host disease.MyD88 Adaptor-Dependent Microbial Sensing by Regulatory T Cells Promotes Mucosal Tolerance and Enforces Commensalism Increased mitochondrial apoptotic priming of human regulatory T cells after allogeneic hematopoietic stem cell transplantation.MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression Nuclear matrix protein SMAR1 control regulatory T-cell fate during inflammatory bowel disease (IBD)Helper T-cell identity and evolution of differential transcriptomes and epigenomes.Signal transducer and activator of transcription 3: a year in review.Essentials of Th17 cell commitment and plasticity Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.Mesenchymal stromal cells: heroes or non-combatants?GRIM19 ameliorates acute graft-versus-host disease (GVHD) by modulating Th17 and Treg cell balance through down-regulation of STAT3 and NF-AT activation.CD226 ligation protects against EAE by promoting IL-10 expression via regulation of CD4+ T cell differentiation.T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia.c-Rel in GVHD biology: a missing link.STAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity.Role of STAT3 in regulatory T lymphocyte plasticity during acute graft-vs.-host-disease Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response.Combined nifuroxazide and SAT05f therapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation.

P2860

Q26751959-8AFEC81B-BBB3-4BC2-ACDE-909320CF5AAC Q26774590-1D559A95-C98B-4EFE-9C11-C03E338D1B20 Q27008946-53C3EF9F-96D9-43F2-99F3-DE44BA865894 Q27335536-B649CFC4-1B18-474A-A981-8022EB69474C Q27687830-D8B36325-A3B3-4C45-9320-93895D0754F5 Q28066083-CA6322EF-C36A-4994-B4A7-3F51137FA602 Q28072627-32661F0C-BD62-4FBC-A3BE-F1C427812B20 Q30419941-68910C7F-C4B5-4101-A0DE-D13559F5234F Q31132719-0195A66E-2A63-4B02-88AB-5B9EA28CE8C7 Q33585268-F2178187-857B-4736-91DA-E5FE7A8E9866 Q33599208-6E8CD505-4087-487E-AF50-CAFF4A8A1096 Q33774610-389FA63B-7483-4999-8ED8-D0003EDCA177 Q33850593-EA4D5D0E-2D0A-45CE-8485-2D382273E654 Q33919580-B784DDF9-83EE-4490-A8D7-58EC5051BD7B Q34009286-00F82390-B510-446A-A40A-31E53DE0CAC6 Q34356521-E917AED6-1418-468F-9ED1-3DA022CF4922 Q34631682-7BABF7EA-0D03-44DF-9C4A-6D42A640721A Q34661115-7C14FA90-269A-4210-85D6-67C0FBA002D0 Q35138124-30E4D831-BED7-48E0-8D86-0A63B5E08466 Q35207094-AA5D9D03-C14A-4FB0-8DD4-C3BBCB19ADF8 Q35607302-03E042DA-AE45-43E5-9C81-B6A62E0E3CD5 Q35613220-79E3C6A7-A579-4197-BFEA-7385945B31DB Q35971439-A47C6AE0-7291-497C-86AB-54333F5A9F7D Q35984305-90D742B6-8101-4E21-BC16-E4C2563929D2 Q36036340-19D0AE9C-7B03-414C-8A37-C69BB98A82E6 Q36109677-76785A7B-ADF3-470C-82F3-46A8105A26F7 Q36605144-86C25562-3EA9-437C-9708-7DDC83741045 Q36623362-47331847-6D5A-4366-9B50-35E2D21A4E54 Q36684441-51C0DEC8-5431-4483-B12A-470D7CF4C41B Q36730400-106F69DA-9E9B-49CC-8DF3-60C8E93C27FB Q36851405-1EE2FECC-8EAF-47E6-9DDE-B99AFE7B8915 Q36975488-EA04E55D-8AAD-4F74-9CBD-FEBA3CBFAB84 Q37080218-6A712C1D-6EDE-4A22-B47D-3C2DAEF9AC9A Q37190048-5AC354DF-3CE3-4016-B816-0CB7829ADAC8 Q37292433-8E9AB46E-68FC-434A-9792-E30ED13E1568 Q37385845-4C38B857-6B88-4647-A65E-19849DA0EA17 Q37496786-8E4C09B4-45DD-4154-B93A-64AC685414C1 Q37529686-F810701C-8288-47DA-A501-ABAA63D863CC Q37552169-F58660EC-DE60-413B-8282-D0E17837D5C8 Q37603497-8F25F70B-60CA-4915-92DA-16B17B4EF50C

P2860

STAT3 transcription factor promotes instability of nTreg cells and limits generation of iTreg cells during acute murine graft-versus-host disease.

http://www.wikidata.org/entity/Q36231545

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

STAT3 transcription factor pro ...... ine graft-versus-host disease.

@ast

STAT3 transcription factor pro ...... ine graft-versus-host disease.

@en

type

label

STAT3 transcription factor pro ...... ine graft-versus-host disease.

@ast

STAT3 transcription factor pro ...... ine graft-versus-host disease.

@en

prefLabel

STAT3 transcription factor pro ...... ine graft-versus-host disease.

@ast

STAT3 transcription factor pro ...... ine graft-versus-host disease.

@en

P1433

Q36231545-875B25B2-5487-4BFA-B3F9-3E94C2FFAA14

P1476

Q36231545-5FEF23FD-BE1F-417A-81D5-22AC3295A223

P2093

Q36231545-1086C988-BD26-4DA9-8BCC-377B779F5111

Q36231545-24F788F4-CEFE-4582-BB90-0E54CAC15D22

Q36231545-6CC319C7-89AE-489F-A487-C38E065A9291

Q36231545-6E0F3F9F-6B37-400C-86A5-63DA424A2E63

Q36231545-7C257262-C680-4D8C-9106-A55C90F2DAAB

Q36231545-ABB9D3AD-4FD0-411D-AB67-5499DCE24AA9

Q36231545-E29A3E99-43BA-4C17-94CF-30BECAD6CFCE

P2860

Q36231545-0F0EC5CF-05CD-4361-80C1-4EF3403AE704

Q36231545-0F63A3C3-BF88-4161-B077-EA8BC4A41AEC

Q36231545-18AB6077-9553-4794-9104-BEB9A1F67A93

Q36231545-19121603-0F12-4F4E-A420-A04F4091A3AC

Q36231545-21E79638-FA5F-4A8E-9BFA-5230ED90ACA2

Q36231545-2652AC00-86B0-445F-8279-A4E07D3B16AB

Q36231545-30BD1027-B093-4D34-A4B7-2AB799C6052B

Q36231545-378D1AF9-48EF-4141-B2AF-6668F051B51A

Q36231545-38EBA445-DA47-422E-A25D-4009EFA05DAE

Q36231545-4274AE3F-D943-4655-8EFE-8B4F35B75708

P304

Q36231545-F0AE3F78-3798-47AE-A095-57DCAF9E342C

P31

Q36231545-AC00443C-27CE-4036-8C78-740A98344A9B

P356

Q36231545-D97F8CA6-3AB7-40AA-AA83-4DBCBC9162F6

P407

Q36231545-EBB5A516-14E1-4CDC-A9AC-445EFA61D93C

P433

Q36231545-1E72A1DF-DB1C-4BEE-9948-F51899196288

P478

Q36231545-1F4818EC-0F62-4B29-A2EC-1123F39FB828

P50

Q36231545-41DAEBF3-45D6-47DA-8909-62D6B7AA3787

P577

Q36231545-119880A3-6E66-43C7-B5B0-B67C46458E8D

P5875

Q36231545-05AE238E-B9FF-4E03-9DE9-9FEE3AFA3F33

P698

Q36231545-E802DE35-7805-411E-B3B5-D5752E572B65

P932

Q36231545-04ABBE38-BAC6-4F32-873A-C4401CB81CAF

P356

J.IMMUNI.2012.05.027

P1433

P1476

STAT3 transcription factor pro ...... rine graft-versus-host disease

@en

P2093

Daniel H Fowler

http://www.w3.org/2001/XMLSchema#string

Jacopo Mariotti

http://www.w3.org/2001/XMLSchema#string

Jason Foley

http://www.w3.org/2001/XMLSchema#string

John J O'Shea

http://www.w3.org/2001/XMLSchema#string

Michael Eckhaus

http://www.w3.org/2001/XMLSchema#string

Shoba Amarnath

http://www.w3.org/2001/XMLSchema#string

Yong Chan Kim

http://www.w3.org/2001/XMLSchema#string

P2860

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

Epigenetic control of the foxp3 locus in regulatory T cells

Regulatory T cells and human myeloid dendritic cells promote tolerance via programmed death ligand-1.

Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection

Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses.

Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I.

P304

209-222

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.IMMUNI.2012.05.027

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

37

http://www.w3.org/2001/XMLSchema#string

P50

P577

2012-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

230740460

http://www.w3.org/2001/XMLSchema#string

P698

22921119

http://www.w3.org/2001/XMLSchema#string

P932

3441059

http://www.w3.org/2001/XMLSchema#string