Topoisomerase II alpha is associated with the mammalian centromere in a cell cycle- and species-specific manner and is required for proper centromere/kinetochore structure.
about
Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell lineCell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activitiesProteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate.How to be a mitotic chromosomePIASgamma is required for faithful chromosome segregation in human cellsDual role of topoisomerase II in centromere resolution and aurora B activityDNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpointSil overexpression in lung cancer characterizes tumors with increased mitotic activityMolecular analysis of core kinetochore composition and assembly in Drosophila melanogasterDNA topoisomerase II distribution in mouse preimplantation embryosCentromere-associated topoisomerase activity in bloodstream form Trypanosoma bruceiThe evolutionary origin of man can be traced in the layers of defunct ancestral alpha satellites flanking the active centromeres of human chromosomesRapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosisCoordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance.Centromere fragmentation is a common mitotic defect of S and G2 checkpoint override.A perikinetochoric ring defined by MCAK and Aurora-B as a novel centromere domain.H2A.Bbd: an X-chromosome-encoded histone involved in mammalian spermiogenesisIn vivo analysis of scaffold-associated regions in Drosophila: a synthetic high-affinity SAR binding protein suppresses position effect variegation.Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation.Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array.How do microbial pathogens make CENs?Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores.The dynamics of DNA topoisomerase IIalpha in living cellsStructure of metaphase chromosomes: a role for effects of macromolecular crowding.The analysis of mutant alleles of different strength reveals multiple functions of topoisomerase 2 in regulation of Drosophila chromosome structure.Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cellsVisualization of early chromosome condensation: a hierarchical folding, axial glue model of chromosome structure.Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage.TOP2Ahigh is the phenotype of recurrence and metastasis whereas TOP2Aneg cells represent cancer stem cells in prostate cancer.Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.A novel chromatin immunoprecipitation and array (CIA) analysis identifies a 460-kb CENP-A-binding neocentromere DNAHow to build a centromere: from centromeric and pericentromeric chromatin to kinetochore assembly.Conserved characteristics of heterochromatin-forming DNA at the 15q11-q13 imprinting center.SUMO modification of DNA topoisomerase II: trying to get a CENse of it allOrganization of highly acetylated chromatin around sites of heterogeneous nuclear RNA accumulationRepetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi.Characterization of HCP-6, a C. elegans protein required to prevent chromosome twisting and merotelic attachment.Centromeric chromosomal translocations show tissue-specific differences between squamous cell carcinomas and adenocarcinomas.Mapping of a human centromere onto the DNA by topoisomerase II cleavage
P2860
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P2860
Topoisomerase II alpha is associated with the mammalian centromere in a cell cycle- and species-specific manner and is required for proper centromere/kinetochore structure.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Topoisomerase II alpha is asso ...... tromere/kinetochore structure.
@ast
Topoisomerase II alpha is asso ...... tromere/kinetochore structure.
@en
type
label
Topoisomerase II alpha is asso ...... tromere/kinetochore structure.
@ast
Topoisomerase II alpha is asso ...... tromere/kinetochore structure.
@en
prefLabel
Topoisomerase II alpha is asso ...... tromere/kinetochore structure.
@ast
Topoisomerase II alpha is asso ...... tromere/kinetochore structure.
@en
P2093
P2860
P356
P1476
Topoisomerase II alpha is asso ...... tromere/kinetochore structure.
@en
P2093
C S Furbee
D P Bazett-Jones
J B Rattner
M J Hendzel
M T Muller
P2860
P304
P356
10.1083/JCB.134.5.1097
P407
P577
1996-09-01T00:00:00Z