Two functional states of the CD11b A-domain: correlations with key features of two Mn2+-complexed crystal structures.
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Crystal structure of the extracellular segment of integrin alpha Vbeta3Binding of anthrax toxin to its receptor is similar to alpha integrin-ligand interactionsCrystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptorCrystal structure of the alpha1beta1 integrin I-domain: insights into integrin I-domain functionAn isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domainEngineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studiesThe Crystal Structure of C2a, the Catalytic Fragment of Classical Pathway C3 and C5 Convertase of Human ComplementStructure of Collagen Receptor Integrin 1I Domain Carrying the Activating Mutation E317AStable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug DesignBiology and structure of leukocyte β 2 integrins and their role in inflammationThe role of alpha and beta chains in ligand recognition by beta 7 integrinsDistinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2Activation of Leukocyte β2-integrinsDifferential effects of serum heat treatment on chemotaxis and phagocytosis by human neutrophils.Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease.Cytosolic free Ca(2+) changes and calpain activation are required for beta integrin-accelerated phagocytosis by human neutrophils.Was it there all the time?Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin beta2 subunit that restrain activation of the integrin alpha(X)beta(2).A minimized human integrin alpha(5)beta(1) that retains ligand recognition.Divalent metal ion coordination by residue T118 of anthrax toxin receptor 2 is not essential for protective antigen binding.Combinatorial libraries against libraries for selecting neoepitope activation-specific antibodies.Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin alphaXbeta2The leukocyte integrins.Anthrax toxin receptor 1/tumor endothelial marker 8: mutation of conserved inserted domain residues overrides cytosolic control of protective antigen bindingNeutrophil adhesive contact dependence on impingement force.Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity.Role of the beta-subunit arginine/lysine finger in integrin heterodimer formation and function.Integrin structure: new twists and turns in dynamic cell adhesion.Application of fluorescent monocytes for probing immune complexes on antigen microarrays.Integrins, cations and ligands: making the connection.Reconstruction of integrin activation.The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18The connection between metal ion affinity and ligand affinity in integrin I domainsDynamic structural changes are observed upon collagen and metal ion binding to the integrin α1 I domain.Platelet glycoprotein ibalpha is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18)Targeting platelet-leukocyte interactions: identification of the integrin Mac-1 binding site for the platelet counter receptor glycoprotein Ibalpha.Structure and mechanics of integrin-based cell adhesion.NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding.Neisseria gonorrhoeae pilin glycan contributes to CR3 activation during challenge of primary cervical epithelial cellsIdentification and characterization of two cation binding sites in the integrin beta 3 subunit.
P2860
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P2860
Two functional states of the CD11b A-domain: correlations with key features of two Mn2+-complexed crystal structures.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Two functional states of the C ...... -complexed crystal structures.
@ast
Two functional states of the C ...... -complexed crystal structures.
@en
type
label
Two functional states of the C ...... -complexed crystal structures.
@ast
Two functional states of the C ...... -complexed crystal structures.
@en
prefLabel
Two functional states of the C ...... -complexed crystal structures.
@ast
Two functional states of the C ...... -complexed crystal structures.
@en
P2093
P2860
P356
P1476
Two functional states of the C ...... -complexed crystal structures.
@en
P2093
P2860
P304
P356
10.1083/JCB.143.6.1523
P407
P577
1998-12-01T00:00:00Z