Mapping of DNase I-hypersensitive sites in the upstream DNA of human embryonic epsilon-globin gene in K562 leukemia cells.
about
The "beta-like-globin" gene domain in human erythroid cellsTransfusion independence and HMGA2 activation after gene therapy of human β-thalassaemiaFetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathiesInteraction of NF-E2 in the human beta-globin locus control region before chromatin remodelingIdentification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome.Requirements for utilization of CREB binding protein by hypersensitive site two of the beta-globin locus control regionDNase I hypersensitivity and epsilon-globin transcriptional enhancement are separable in locus control region (LCR) HS1 mutant human beta-globin YAC transgenic miceAn erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes.Interaction of epsilon-globin cis-acting control elements with erythroid-specific regulatory macromolecules.Cis- and trans-acting elements responsible for the cell-specific expression of the human alpha 1-antitrypsin geneChromatin structure of transcriptionally active and inactive human c-myc allelesChromatin structure of the murine c-myc locus: implications for the regulation of normal and chromosomally translocated genes.Enhancement of beta-globin locus control region-mediated transactivation by mitogen-activated protein kinases through stochastic and graded mechanismsThe beta-globin locus control region versus gene therapy vectors: a struggle for expression.Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region.Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain.Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene.Rapid and reversible changes in nucleosome structure accompany the activation, repression, and superinduction of murine fibroblast protooncogenes c-fos and c-myc.Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells.Transcriptional Enhancers: Bridging the Genome and Phenome.c-myc gene inactivation during induced maturation of HL-60 cells. Transcriptional repression and loss of a specific DNAse I hypersensitive site.Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code.Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities.Effective automated feature construction and selection for classification of biological sequences.A developmentally stable chromatin structure in the human beta-globin gene clusterDevelopmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain.Mutation of gene-proximal regulatory elements disrupts human epsilon-, gamma-, and beta-globin expression in yeast artificial chromosome transgenic miceHighly restricted localization of RNA polymerase II within a locus control region of a tissue-specific chromatin domain.Synergism between hypersensitive sites confers long-range gene activation by the beta-globin locus control region.Mitogen-activated protein kinases enhance long-range activation by the beta-globin locus control region.The A gamma-globin 3' element provides no unique function(s) for human beta-globin locus gene regulation.Biological, cellular, and molecular characteristics of an inducible transgenic skin tumor model: a review.Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control regionHigh levels of human gamma-globin gene expression in adult mice carrying a transgene of deletion-type hereditary persistence of fetal hemoglobinPosition independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element.Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoterNegative regulation of the human epsilon-globin gene by transcriptional interference: role of an Alu repetitive element.Humanized Mouse Model of Cooley's Anemia.Transcriptional mechanisms underlying hemoglobin synthesis.Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structure
P2860
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P2860
Mapping of DNase I-hypersensitive sites in the upstream DNA of human embryonic epsilon-globin gene in K562 leukemia cells.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
@wuu
1984年学术文章
@zh-cn
1984年学术文章
@zh-hans
1984年学术文章
@zh-my
1984年学术文章
@zh-sg
1984年學術文章
@yue
1984年學術文章
@zh
1984年學術文章
@zh-hant
name
Mapping of DNase I-hypersensit ...... n gene in K562 leukemia cells.
@ast
Mapping of DNase I-hypersensit ...... n gene in K562 leukemia cells.
@en
type
label
Mapping of DNase I-hypersensit ...... n gene in K562 leukemia cells.
@ast
Mapping of DNase I-hypersensit ...... n gene in K562 leukemia cells.
@en
prefLabel
Mapping of DNase I-hypersensit ...... n gene in K562 leukemia cells.
@ast
Mapping of DNase I-hypersensit ...... n gene in K562 leukemia cells.
@en
P2860
P356
P1476
Mapping of DNase I-hypersensit ...... n gene in K562 leukemia cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.81.9.2718
P407
P577
1984-05-01T00:00:00Z