Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling. - Wikidata - wikimedia - TriplyDB

Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

http://www.wikidata.org/entity/Q36279107

about

Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans Metabolic actions of Rho-kinase in periphery and brain The brain and brown fat Brain regulation of energy balance and body weight.Hypothalamic control of brown adipose tissue thermogenesis Rho-kinase inhibition ameliorates metabolic disorders through activation of AMPK pathway in mice Diverse matrix metalloproteinase functions regulate cancer amoeboid migration Leptin and insulin signaling in dopaminergic neurons: relationship between energy balance and reward system.FOXO1 downregulation contributes to the oncogenic program of primary mediastinal B-cell lymphoma.Role of nociceptor estrogen receptor GPR30 in a rat model of endometriosis pain.Minireview: CNS Mechanisms of Leptin Action.Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress.Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress.ROCK1 in AgRP neurons regulates energy expenditure and locomotor activity in male mice.Senescence Mediated by p16INK4a Impedes Reprogramming of Human Corneal Endothelial Cells into Neural Crest Progenitors.Leptin signaling is required for leucine deprivation-enhanced energy expenditure.ROCK-isoform-specific polarization of macrophages associated with age-related macular degeneration.ROCK1 isoform-specific deletion reveals a role for diet-induced insulin resistance ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth.The Leptin Receptor Complex: Heavier Than Expected?Leptin signalling pathways in hypothalamic neurons.The Circadian System: A Regulatory Feedback Network of Periphery and Brain.Central Angiotensin-II Increases Blood Pressure and Sympathetic Outflow via Rho Kinase Activation in Conscious Rabbits.RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma.The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity.Connecting metabolism to intestinal barrier function: The role of leptin.ROCKing the JAKs.The effects of exercise on hypothalamic neurodegeneration of Alzheimer's disease mouse model.Anti-adipogenic effects of KD025 (SLx-2119), a ROCK2-specific inhibitor, in 3T3-L1 cells.Neotomodon alstoni mice present sex differences between lean and obese in daily hypothalamic leptin signaling.DNA methylation regulates hypothalamic gene expression linking parental diet during pregnancy to the offspring's risk of obesity in Psammomys obesus.POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels.Myokine IL-15 regulates the crosstalk of co-cultured porcine skeletal muscle satellite cells and preadipocytes.RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation.Leptin Function and Regulation.

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Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

http://www.wikidata.org/entity/Q36279107

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2012年學術文章

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2012年學術文章

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Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

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Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

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Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

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Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

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Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

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Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

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Nature Neuroscience

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Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.

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Bonghee Lee

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Bradford B Lowell

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Chianping Ye

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Christian Bjørbæk

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Dae Ho Lee

http://www.w3.org/2001/XMLSchema#string

Dong Kong

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Hu Huang

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Janice M Zabolotny

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Kyung Hee Byun

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Min Seon Kim

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P2860

Hypothalamic mTOR signaling regulates food intake

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

Divergent signaling capacities of the long and short isoforms of the leptin receptor

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho

Central nervous system control of food intake and body weight

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.

Fluorescence cross-correlation spectroscopy in living cells.

From lesions to leptin: hypothalamic control of food intake and body weight.

Central leptin receptor action and resistance in obesity.

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10.1038/NN.3207

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3458121

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