Transcription-independent pro-apoptotic functions of p53.
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p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylaseTATA binding protein associated factor 3 (TAF3) interacts with p53 and inhibits its functionBAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groovep53 Activation following Rift Valley fever virus infection contributes to cell death and viral productionMDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathwayChloroquine activates the p53 pathway and induces apoptosis in human glioma cellsAutophagy in malignant transformation and cancer progressionUncovering the role of p53 splice variants in human malignancy: a clinical perspectiveEngineered Nanoparticles Against MDR in Cancer: The State of the Art and its Prospective.Emerging Non-Canonical Functions and Regulation by p53: p53 and StemnessThe Importance of Physiologically Relevant Cell Lines for Studying Virus-Host Interactionsp53 Acetylation: Regulation and ConsequencesInhibition of Crm1-p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ationIncreased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primatesAPLP1, Alzheimer's-like pathology and neurodegeneration in the frontal cortex of manganese-exposed non-human primatesCHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancerMitochondrial uncoupling inhibits p53 mitochondrial translocation in TPA-challenged skin epidermal JB6 cellsThe anti-cancer activities of Vernonia amygdalina extract in human breast cancer cell lines are mediated through caspase-dependent and p53-independent pathwaysPulchrin A, a New Natural Coumarin Derivative of Enicosanthellum pulchrum, Induces Apoptosis in Ovarian Cancer Cells via Intrinsic PathwayAdenovirus type 5 early region 1B 55-kDa oncoprotein can promote cell transformation by a mechanism independent from blocking p53-activated transcriptionDirect promoter induction of p19Arf by Pit-1 explains the dependence receptor RET/Pit-1/p53-induced apoptosis in the pituitary somatotroph cellsHbo1 Links p53-dependent stress signaling to DNA replication licensing.Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity.p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrestComputational identification of transcriptional regulators in human endotoxemiaRegulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway.Substituted E-3-(3-indolylmethylene)-1,3-dihydroindol-2-ones with antitumor activity. In depth study of the effect on growth of breast cancer cells.Nuclear transcription factors in mammalian mitochondriaDirect interaction between p53 and Tid1 proteins affects p53 mitochondrial localization and apoptosis.p53 Family and Cellular Stress Responses in Cancer.SUMO--a post-translational modification with therapeutic potential?Blockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis.bis-Dehydroxy-Curcumin triggers mitochondrial-associated cell death in human colon cancer cells through ER-stress induced autophagy.Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2.Profiling drug-induced cell death pathways in the zebrafish lateral line.MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis.Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complexComparative transcriptome profiling of an SV40-transformed human fibroblast (MRC5CVI) and its untransformed counterpart (MRC-5) in response to UVB irradiation.CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53.
P2860
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P2860
Transcription-independent pro-apoptotic functions of p53.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Transcription-independent pro-apoptotic functions of p53.
@ast
Transcription-independent pro-apoptotic functions of p53.
@en
type
label
Transcription-independent pro-apoptotic functions of p53.
@ast
Transcription-independent pro-apoptotic functions of p53.
@en
prefLabel
Transcription-independent pro-apoptotic functions of p53.
@ast
Transcription-independent pro-apoptotic functions of p53.
@en
P2093
P1476
Transcription-independent pro-apoptotic functions of p53.
@en
P2093
Daniel Speidel
Sonja Wolff
Ute M Moll
Wolfgang Deppert
P304
P356
10.1016/J.CEB.2005.09.007
P577
2005-10-13T00:00:00Z