Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis - Wikidata - wikimedia - TriplyDB

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

http://www.wikidata.org/entity/Q36290297

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Novel GATA6 mutations in patients with pancreatic agenesis and congenital heart malformations Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biology Pancreas-specific Cre driver lines and considerations for their prudent use Silencing Mist1 Gene Expression Is Essential for Recovery from Acute Pancreatitis Natural history of β-cell adaptation and failure in type 2 diabetes Transcription factor regulation of pancreatic organogenesis, differentiation and maturation The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis Many faces of monogenic diabetes The MafA transcription factor becomes essential to islet β-cells soon after birth.MicroRNA-7a regulates pancreatic β cell function.Pancreas and gallbladder agenesis in a newborn with semilobar holoprosencephaly, a case report.Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis.GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development.Revealing transcription factors during human pancreatic β cell development.Human pluripotent stem cells: an emerging model in developmental biology.Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas Function of GATA factors in the adult mouse liver.Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors VISIONET: intuitive visualisation of overlapping transcription factor networks, with applications in cardiogenic gene discovery.TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors.Simultaneous gene deletion of gata4 and gata6 leads to early disruption of follicular development and germ cell loss in the murine ovary.Adrenal Development in Mice Requires GATA4 and GATA6 Transcription Factors A loss-of-function and H2B-Venus transcriptional reporter allele for Gata6 in mice GATA4 is essential for bone mineralization via ERα and TGFβ/BMP pathways.The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development.GATA4 and GATA6 control mouse pancreas organogenesis.GATA believe it: new essential regulators of pancreas development.GATA factors in endocrine neoplasia GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling.Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility.Mouse muscle as an ectopic permissive site for human pancreatic development.Development of the human pancreas from foregut to endocrine commitment.SIRT1 deacetylates FOXA2 and is critical for Pdx1 transcription and β-cell formation.GATA factors promote ER integrity and β-cell survival and contribute to type 1 diabetes risk.Gene regulatory networks governing pancreas development.Transcriptional control of mammalian pancreas organogenesis.Cellular reprogramming for pancreatic β-cell regeneration: clinical potential of small molecule control.Derivation of Endodermal Progenitors From Pluripotent Stem Cells.Epigenetic modifications and long noncoding RNAs influence pancreas development and function.Pancreatic islet cell development and regeneration.

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P2860

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

http://www.wikidata.org/entity/Q36290297

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

@ast

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

@en

type

label

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

@ast

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

@en

prefLabel

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

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Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

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P1433

Journal of Clinical Investigation

P1476

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

@en

P2093

Kimberly J Decker

http://www.w3.org/2001/XMLSchema#string

Lori Sussel

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Michael A Hale

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Michele A Battle

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Raymond J Macdonald

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Shouhong Xuan

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P2860

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart

Pioneer transcription factors: establishing competence for gene expression

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

Generalized lacZ expression with the ROSA26 Cre reporter strain

The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal pulmonary development

GATA6 regulates differentiation of distal lung epithelium

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10.1172/JCI63352

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10

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P478

122

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Stephen A. Duncan

Matthew J Borok

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2012-09-24T00:00:00Z

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23006325

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Aizkuņģa dziedzeris

P932

3461916

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