Human AP endonuclease 1 (HAP1) protein expression in breast cancer correlates with lymph node status and angiogenesis
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Isolation of a small molecule inhibitor of DNA base excision repair.Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers.Prognostic value of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in breast cancer.Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1.Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1.Regulation of DNA repair by S-nitrosylation.Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor propertiesDesign and activity of AP endonuclease-1 inhibitors.Subcellular localization of APE1/Ref-1 in human hepatocellular carcinoma: possible prognostic significance.Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis.APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.Base excision repair: contribution to tumorigenesis and target in anticancer treatment paradigmsA gene encoding an apurinic/apyrimidinic endonuclease-like protein is up-regulated in human gastric cancer.Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.Colon cancer progression is driven by APEX1-mediated upregulation of JaggedHuman apurinic/apyrimidinic endonuclease 1.DNA Repair Endonucleases: Physiological Roles and Potential as Drug Targets.Structure-based virtual screening toward the discovery of novel inhibitors of the DNA repair activity of the human apurinic/apyrimidinic endonuclease 1.Apurinic/apyrimidinic endonuclease 1 (APE1/Ref-1) overexpression is an independent prognostic marker in prostate cancer without TMPRSS2:ERG fusion.Impact of apurinic/apyrimidinic endonuclease 1/redox factor-1 on treatment response and survival in oral squamous cell carcinoma.Receptor-based virtual screening and biological characterization of human apurinic/apyrimidinic endonuclease (Ape1) inhibitors.Nuclear localization of human AP endonuclease 1 (HAP1/Ref-1) associates with prognosis in early operable non-small cell lung cancer (NSCLC).The APE1 redox inhibitor E3330 reduces collective cell migration of human breast cancer cells and decreases chemoinvasion and colony formation when combined with docetaxel.Bu-Fei decoction and modified Bu-Fei decoction inhibit the growth of non-small cell lung cancer, possibly via inhibition of apurinic/apyrimidinic endonuclease 1.Apurinic/apyrimidinic endonuclease 1 (APE1) is overexpressed in malignant transformation of salivary gland pleomorphic adenoma.Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic.Dysregulation of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in advanced retinoblastoma.Prognostic significance of APE1 cytoplasmic localization in human epithelial ovarian cancer.
P2860
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P2860
Human AP endonuclease 1 (HAP1) protein expression in breast cancer correlates with lymph node status and angiogenesis
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Human AP endonuclease 1 (HAP1) ...... h node status and angiogenesis
@ast
Human AP endonuclease 1 (HAP1) ...... h node status and angiogenesis
@en
type
label
Human AP endonuclease 1 (HAP1) ...... h node status and angiogenesis
@ast
Human AP endonuclease 1 (HAP1) ...... h node status and angiogenesis
@en
prefLabel
Human AP endonuclease 1 (HAP1) ...... h node status and angiogenesis
@ast
Human AP endonuclease 1 (HAP1) ...... h node status and angiogenesis
@en
P2093
P2860
P356
P1476
Human AP endonuclease 1 (HAP1) ...... h node status and angiogenesis
@en
P2093
Hickson ID
Kaklamanis L
Kakolyris S
P2860
P2888
P304
P356
10.1038/BJC.1998.194
P407
P577
1998-04-01T00:00:00Z