Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts
about
Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structuresThe MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formationThe cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)Structural basis for L27 domain-mediated assembly of signaling and cell polarity complexesDistinct roles of Galphai and Gbeta13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisionsArl2- and Msps-dependent microtubule growth governs asymmetric divisionaPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermisHedgehog signaling acts with the temporal cascade to promote neuroblast cell cycle exitLGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA PathwaysDown-regulated expression of atypical PKC-binding domain deleted asip isoforms in human hepatocellular carcinomashINADl/PATJ, a homolog of discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cellsAsymmetric cell division of stem and progenitor cells during homeostasis and cancerPKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivityAssociation of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cellsWillin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylationDrosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity.Signaling pathways in cell polarity.Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.Widely conserved signaling pathways in the establishment of cell polarityPARtitioning numb.Hedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning.Apical polarity protein PrkCi is necessary for maintenance of spinal cord precursors in zebrafish.A critical step for postsynaptic F-actin organization: regulation of Baz/Par-3 localization by aPKC and PTENPar6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesisRho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongation.A region-specific neurogenesis mode requires migratory progenitors in the Drosophila visual system.An apicobasal gradient of Rac activity determines protrusion form and positionThe kinesin-associated protein UNC-76 is required for axonal transport in the Drosophila nervous system.DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.Spermatid cyst polarization in Drosophila depends upon apkc and the CPEB family translational regulator orb2Multiple domains in the Crumbs Homolog 2a (Crb2a) protein are required for regulating rod photoreceptor size.Exocyst-mediated membrane trafficking is required for branch outgrowth in Drosophila tracheal terminal cells.Binding to PKC-3, but not to PAR-3 or to a conventional PDZ domain ligand, is required for PAR-6 function in C. elegansComplex interactions between GSK3 and aPKC in Drosophila embryonic epithelial morphogenesis.aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cellsBazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila.Bazooka and atypical protein kinase C are required to regulate oocyte differentiation in the Drosophila ovaryDrosophila neuroblasts as a new model for the study of stem cell self-renewal and tumour formation.Establishment of epithelial polarity--GEF who's minding the GAP?Apical accumulation of the Sevenless receptor tyrosine kinase during Drosophila eye development is promoted by the small GTPase Rap1
P2860
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P2860
Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
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2000年学术文章
@zh-my
2000年学术文章
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2000年學術文章
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name
Drosophila atypical protein ki ...... y of epithelia and neuroblasts
@ast
Drosophila atypical protein ki ...... y of epithelia and neuroblasts
@en
type
label
Drosophila atypical protein ki ...... y of epithelia and neuroblasts
@ast
Drosophila atypical protein ki ...... y of epithelia and neuroblasts
@en
prefLabel
Drosophila atypical protein ki ...... y of epithelia and neuroblasts
@ast
Drosophila atypical protein ki ...... y of epithelia and neuroblasts
@en
P2093
P2860
P356
P1476
Drosophila atypical protein ki ...... y of epithelia and neuroblasts
@en
P2093
P2860
P304
P356
10.1083/JCB.150.6.1361
P407
P577
2000-09-01T00:00:00Z