The ras signaling pathway mimics insulin action on glucose transporter translocation
about
Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase)Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesiclesRequirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transporteIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcriptionE4orf1: a novel ligand that improves glucose disposal in cell cultureBeta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway.The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake.Exposure to p,p'-dichlorodiphenyldichloroethylene (DDE) induces fasting hyperglycemia without insulin resistance in male C57BL/6H miceInsulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade.The metabolic demands of cancer cells are coupled to their size and protein synthesis ratesThe role of small G-proteins in the regulation of glucose transport (review).Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance.Ras signaling in the activation of glucose transport by insulin.Insulin receptor substrate 1 rescues insulin action in CHO cells expressing mutant insulin receptors that lack a juxtamembrane NPXY motif.Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cellsInsulin receptor-independent upregulation of cellular glucose uptakeApoA-IV improves insulin sensitivity and glucose uptake in mouse adipocytes via PI3K-Akt Signaling.Increased glucose transport in ras-transformed fibroblasts: a possible role for N-glycosylation of GLUT1.The insulin-dependent biosynthesis of GLUT1 and GLUT3 glucose transporters in L6 muscle cells is mediated by distinct pathways. Roles of p21ras and pp70 S6 kinase.Ethanol inhibits insulin receptor substrate-1 tyrosine phosphorylation and insulin-stimulated neuronal thread protein gene expression.Activation of the Ras/mitogen-activated protein kinase signaling pathway alone is not sufficient to induce glucose uptake in 3T3-L1 adipocytes.Roles of insulin, guanosine 5'-[gamma-thio]triphosphate and phorbol 12-myristate 13-acetate in signalling pathways of GLUT4 translocation.Localization of sequences for the basal and insulin-like growth factor-I inducible activity of the fatty acid synthase promoter in 3T3-L1 fibroblasts.Insulin regulation of membrane-associated insulin receptor substrate 1.Stimulation of protein phosphatase-1 activity by insulin in rat adipocytes. Evaluation of the role of mitogen-activated protein kinase pathway.Overexpression of Ha-ras selectively in adipose tissue of transgenic mice. Evidence for enhanced sensitivity to insulin.Overexpression of catalytic subunit p110alpha of phosphatidylinositol 3-kinase increases glucose transport activity with translocation of glucose transporters in 3T3-L1 adipocytes.Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport.Profibrotic up-regulation of glucose transporter 1 by TGF-β involves activation of MEK and mammalian target of rapamycin complex 2 pathways.Roles of PI 3-kinase and Ras on insulin-stimulated glucose transport in 3T3-L1 adipocytes.Sorbitol activates atypical protein kinase C and GLUT4 glucose transporter translocation/glucose transport through proline-rich tyrosine kinase-2, the extracellular signal-regulated kinase pathway and phospholipase D.Inactivation of glycogen synthase kinase-3 by epidermal growth factor is mediated by mitogen-activated protein kinase/p90 ribosomal protein S6 kinase signaling pathway in NIH/3T3 cells.Characterization of the intracellular signalling pathways that underlie growth-factor-stimulated glucose transport in Xenopus oocytes: evidence for ras- and rho-dependent pathways of phosphatidylinositol 3-kinase activation.Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants.DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders.Cultured neonatal rat cardiomyocytes display differences in glucose uptake and sensitivity to dexamethasone related to maternal diet
P2860
Q24533586-E50D0151-3927-4CB8-AA34-D869BEE3EEC7Q28138791-BDB2AAF5-8EE1-4229-B2EC-4EFCB7649C11Q28577282-E971D078-36ED-4B25-A40F-1C95F7BA6393Q28586333-50F13E22-CF06-4517-859F-3AC304BC2AC5Q28741118-BD9E8694-88DF-4C29-96DA-4A36D387E542Q30452664-AD348409-8003-4ACD-8347-5723F8D4ABC9Q33829309-7CF23B10-1C0B-44F0-B09A-5983509C3863Q33903748-50F0F3BD-8A18-4B76-9E93-0991CBE4F94CQ33942025-700DB8B5-0D12-4DD1-AEA2-62D5B0D5CACDQ34258905-F308AB3B-B934-46DB-AAE2-4ACEC116009FQ34420448-620C2EFA-FD8B-4CC7-8F2D-B45199808D7DQ34955984-1D99A4B0-908B-4F20-9FEA-638AAFC49DF1Q35258436-ABF269DC-80E1-48DB-8D94-59747E633D10Q36554166-ED806E1F-8FF0-4F05-87A8-8D26391DF464Q36555172-5985794C-83D6-4B07-879F-E5F8879793D4Q36826889-F618596C-3B0F-4327-B6FD-CE6690F9E768Q37602217-E1016700-A859-4678-8060-8401E505A0ECQ41110834-DF33AEE6-8DD7-4339-BEB4-520933B4C6EDQ41281641-0B643BBF-E154-4D29-A4A2-C29BBF187662Q41311369-72B6A4DB-C9A3-4C5F-A8D1-255BFAB73C4EQ42001983-95D420B0-168B-425D-ACFF-24D2E186ACBCQ42160185-F11A6414-7061-4E8B-9CFE-242CA4CF584FQ42475771-2681B77B-74C7-472E-A595-4CE762481351Q42479679-8E34314E-DFDE-460D-BF6F-346A6181115EQ42487960-6D0E01DB-6A6B-4AA4-9926-8D611EA3A073Q42517372-2A09DE94-5A39-42B1-9F2D-781BEADF31EAQ42518882-B23F0715-2339-4D46-8E09-B7F8F16B8CD6Q42528828-A6C641E2-408B-40B7-9CFB-1F5802A1179DQ42705478-141663F0-77A1-425B-81E9-184796935E7AQ42803976-DD1D80AE-A818-4A7E-A475-09D47304B4C1Q42817970-3DA12FDD-2737-4FCA-B1D0-416520675D3DQ42830614-312D25BC-2C48-4C5F-948D-5D958EC9B2D9Q42987313-D3CA6AD6-798D-474A-A959-493074A06B9EQ45810128-8785EDA9-B7C8-4C57-BF62-2F347C148F54Q55396891-B4C63A05-AC66-4126-A19D-01B2E839DB21Q57659843-19FF0705-63A1-4A3D-9FBA-CC0EFB1E7DCC
P2860
The ras signaling pathway mimics insulin action on glucose transporter translocation
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
The ras signaling pathway mimics insulin action on glucose transporter translocation
@ast
The ras signaling pathway mimics insulin action on glucose transporter translocation
@en
type
label
The ras signaling pathway mimics insulin action on glucose transporter translocation
@ast
The ras signaling pathway mimics insulin action on glucose transporter translocation
@en
prefLabel
The ras signaling pathway mimics insulin action on glucose transporter translocation
@ast
The ras signaling pathway mimics insulin action on glucose transporter translocation
@en
P2093
P2860
P921
P356
P1476
The ras signaling pathway mimics insulin action on glucose transporter translocation
@en
P2093
J Klarlund
K Baltensperger
P2860
P304
P356
10.1073/PNAS.90.10.4460
P407
P577
1993-05-01T00:00:00Z