Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer
about
The zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cellsActive specific immunotherapy targeting the Wilms' tumor protein 1 (WT1) for patients with hematological malignancies and solid tumors: lessons from early clinical trialsIkaros gene expression and leukemiaProstate cancer invasion and metastasis: insights from mining genomic data.A functional screen for genes inducing epidermal growth factor autonomy of human mammary epithelial cells confirms the role of amphiregulin.WT1 gene expression as a prognostic marker in advanced serous epithelial ovarian carcinoma: an immunohistochemical study.The plasticizer butyl benzyl phthalate induces genomic changes in rat mammary gland after neonatal/prepubertal exposure.Analysis of gene expression in prostate cancer epithelial and interstitial stromal cells using laser capture microdissection.The Wilms' tumor suppressor WT1 induces estrogen-independent growth and anti-estrogen insensitivity in ER-positive breast cancer MCF7 cells.Prognostic significance of WT1 expression in soft tissue sarcoma.A mammal-specific exon of WT1 is not required for development or fertility.Knockdown of splicing factor SRp20 causes apoptosis in ovarian cancer cells and its expression is associated with malignancy of epithelial ovarian cancer.Dysregulated methylation at imprinted genes in prostate tumor tissue detected by methylation microarray.Prognostic significance of specific anti-WT1 IgG antibody level in plasma in patients with ovarian carcinomaThe Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis.Transcription factor decoy (TFD) in breast cancer research and treatment.WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrome: therapeutic potential of WT1 targeted therapies.WT1/EGR1-mediated control of STIM1 expression and function in cancer cellsInsights into the physiological role of WT1 from studies of genetically modified mice.WT1 gene transcript assay for relapse in acute leukemia after transplantation.The Wilms' tumour suppressor protein WT1 acts as a key transcriptional repressor of the human thromboxane A2 receptor gene in megakaryocytes.The Wilms' tumor suppressor WT1 regulates expression of members of the epidermal growth factor receptor (EGFR) and estrogen receptor in acquired tamoxifen resistance.Antigen-specific cellular immunotherapy of leukemia.The Wilms' tumor suppressor WT1 inhibits malignant progression of neoplastigenic mammary epithelial cells.WT1 marker is not sufficient for distinguishing between melanoma and melanocytic nevi.Wilms' Tumour gene 1 (WT1) as an immunotherapeutic targetWT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel.Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematological disorders.The ratio of +/-KTS splice variants of the Wilms' tumour suppressor protein WT1 mRNA is determined by an intronic enhancer.Expression of the Wilms' tumor gene WT1 in solid tumors and its involvement in tumor cell growth.Activation of the WT1 tumor suppressor gene promoter by Pea3.Expression of Wilms' tumor gene (WT1) is associated with survival in malignant pleural mesothelioma.Gemcitabine enhances Wilms' tumor gene WT1 expression and sensitizes human pancreatic cancer cells with WT1-specific T-cell-mediated antitumor immune response.Estrogen receptor-alpha (ER-alpha) suppresses expression of its variant ER-alpha 36.Wilms' tumor protein 1: an early target of progestin regulation in T-47D breast cancer cells that modulates proliferation and differentiation.HER2/neu increases the expression of Wilms' Tumor 1 (WT1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cells.Transcriptional activation of c-myc proto-oncogene by WT1 protein.WT1-p53 interactions in insulin-like growth factor-I receptor gene regulation.Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells.Hypermethylation of the Wilms' tumor suppressor gene CpG island in human breast carcinomas.
P2860
Q21195233-7C3E8EBC-1880-48C7-98E7-5F50D2D468C8Q27026836-6F8B70BA-3A4C-4D86-B400-ACE0C83F3492Q28208988-6E8F88F4-B9C5-47EF-B5D3-299F488CEBD3Q30656758-8E02FB10-8E03-44E5-B378-CDF11DFCF158Q30999913-CD9750E0-6355-4E7B-B911-D098CB2B677BQ33239524-49FAC5A3-36FA-4CF6-B14A-101C64095880Q33308926-492CC649-F435-4B72-BF4E-E013E6A6DA39Q33567270-5F8542C0-4733-48E0-AA12-67BB98A8D5ACQ33723383-D150F5EE-43AA-40F3-AECE-2405A10709DAQ33965010-68073729-682E-4EBF-AFF4-8FD62EA582A4Q34281674-EB4A3F76-38D9-4372-A913-CA6A8666FDFEQ34441008-EE78ED24-B867-4B90-A2B1-F33286298E3BQ34869462-5FB20AA4-795F-480B-9B8A-77E295DEAD85Q35000449-15BE5A9D-4A02-4086-BF5E-632631FC1FE1Q35033140-009EE472-3FB7-452C-8D87-BE00FA731514Q35081110-B57DB3A2-3DD9-417C-900B-0B80B5DD7CA0Q35166856-C424043A-4786-41A8-9C82-CE6FF96E37E6Q35575649-B68FD054-95DB-4D56-A7D7-24F0844DA9E3Q35668754-3729F842-6B8B-498A-997C-FC520EE03EC0Q35821007-99530887-F0AB-4A95-8D70-D7DDD0469744Q35889126-5DB42DA6-A16C-40A6-BD5F-16066DB83914Q36049015-75789415-07DA-48B3-AB49-55449EED32B9Q36240201-5C5B2DDE-D946-484F-868B-AB519885F153Q37121492-7C2942D7-BB4A-4D48-AEFA-E94DC1F58485Q37180764-1D961ABC-38B2-4B0C-A103-2416DBAF7B94Q37704104-77584176-3F8C-4860-B113-5802CEE481D9Q37721627-BF5D1FB7-311C-4B0E-A62E-70AEAD5C4EAEQ38017093-4720AC4D-A9F7-4D92-B109-660B4EE06653Q38287924-56BD7A66-CAE3-4570-8D97-3E496263B3B4Q38326365-27B3C951-13F3-4169-BEDE-69081593ADE2Q38344327-E5173A3B-9ECD-43DD-A89E-48B43C1B9C6AQ39298123-E2C78B43-51D9-4CC9-ACF3-5C4EEA407738Q39537513-331617C1-40D2-4969-940C-6330BD0A3F57Q39867285-56AA9514-0A32-40F6-B048-1D5E7315D45CQ40114088-452CF16F-38AC-4C32-A7E0-228F60B0D5C8Q40464845-EA57A80B-333B-4D3A-9164-B26F4C23F39AQ40529835-484E1BFE-2939-424C-A061-09C464D695E4Q40688483-A087E0DE-38F1-4A14-B5E9-5FD3AF9EAD36Q40694264-A06424D8-95B2-4B7F-A29F-0D478BEDE81BQ40794277-D829500B-D226-43B0-96DB-B4918F57E560
P2860
Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer
@ast
Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer
@en
type
label
Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer
@ast
Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer
@en
prefLabel
Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer
@ast
Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer
@en
P2093
P2860
P356
P1476
Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer
@en
P2093
C W Daniel
G B Silberstein
K Van Horn
P Strickland
P2860
P304
P356
10.1073/PNAS.94.15.8132
P407
P577
1997-07-01T00:00:00Z