Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells. - Wikidata - wikimedia - TriplyDB

Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells.

Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells.

http://www.wikidata.org/entity/Q40694264

about

Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer model Active Stat3 is required for survival of human squamous cell carcinoma cells in serum-free conditions ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity Mitochondrial Stat3, the Need for Design Thinking miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells STAT3 can be activated through paracrine signaling in breast epithelial cells.Bcl-x(L)-mediated changes in metabolic pathways of breast cancer cells: from survival in the blood stream to organ-specific metastasis.Growth-suppressive activity of raloxifene on liver cancer cells by targeting IL-6/GP130 signaling.Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)Repositioning Bazedoxifene as a novel IL-6/GP130 signaling antagonist for human rhabdomyosarcoma therapy Association of toxicity of sorafenib and sunitinib for human keratinocytes with inhibition of signal transduction and activator of transcription 3 (STAT3)A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells.Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors.Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells.Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells.SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma Trefoil factor 3 is oncogenic and mediates anti-estrogen resistance in human mammary carcinoma Breast cancer metastasis to the central nervous system Different protein expression associated with chemotherapy response in oropharyngeal cancer according to HPV status.Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma Profiling of alternative polyadenylation sites in luminal B breast cancer using the SAPAS method.Chemosensitization of tumors by resveratrol Trefoil factor 3 promotes metastatic seeding and predicts poor survival outcome of patients with mammary carcinoma.Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030.A novel curcumin analog (H-4073) enhances the therapeutic efficacy of cisplatin treatment in head and neck cancer Nifuroxazide induces apoptosis and impairs pulmonary metastasis in breast cancer model.A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance?Artocarpus altilis (Parkinson) Fosberg Extracts and Geranyl Dihydrochalcone Inhibit STAT3 Activity in Prostate Cancer DU145 Cells.Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells.A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells.STAT3 positively regulates an early step in B-cell development.Elevated serum IL-10 levels in diffuse large B-cell lymphoma: a mechanism of aberrant JAK2 activation.STAT proteins as novel targets for cancer drug discovery.Constitutive activation of Stat3 signaling pathway in human colorectal carcinoma.

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P2860

Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells.

http://www.wikidata.org/entity/Q40694264

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2002 nî lūn-bûn

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Resistance to chemotherapy via ...... etastatic breast cancer cells.

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Resistance to chemotherapy via ...... etastatic breast cancer cells.

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Resistance to chemotherapy via ...... etastatic breast cancer cells.

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Ana De Juan

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Angels Sierra

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Jose L Fernandez-Luna

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Jose M Lopez-Vega

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Pedro J Real

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P2860

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

Stat3 as an oncogene

Escaping cell death: survival proteins in cancer.

Prognostic significance of apoptosis regulators in breast cancer.

17beta-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two estrogen-responsive elements present in the coding sequence.

Studies of epidermal growth factor receptor inhibition in breast cancer.

Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer

Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis

Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis.

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50

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21

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Jose Carlos Segovia

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