In vitro efficacy of new antifolates against trimethoprim-resistant Bacillus anthracis.
about
Targeted mutations of Bacillus anthracis dihydrofolate reductase condense complex structure−activity relationshipsCrystal Structure of Bacillus anthracis Dihydrofolate Reductase with the Dihydrophthalazine-Based Trimethoprim Derivative RAB1 Provides a Structural Explanation of Potency and SelectivityX-ray structure of the ternary MTX.NADPH complex of the anthrax dihydrofolate reductase: a pharmacophore for dual-site inhibitor designInhibition of Antibiotic-Resistant Staphylococcus aureus by the Broad-Spectrum Dihydrofolate Reductase Inhibitor RAB1Inhibition of Bacterial Dihydrofolate Reductase by 6-Alkyl-2,4-diaminopyrimidinesStructure–activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductaseThe Structure and Competitive Substrate Inhibition of Dihydrofolate Reductase from Enterococcus faecalis Reveal Restrictions to Cofactor DockingMetabolic network analysis-based identification of antimicrobial drug targets in category A bioterrorism agentsHigh-throughput screening of a diversity collection using biodefense category A and B priority pathogensSynthesis and biological evaluation of 2,4-diaminopyrimidine-based antifolate drugs against Bacillus anthracis.New developments in vaccines, inhibitors of anthrax toxins, and antibiotic therapeutics for Bacillus anthracis.Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracisIdentification of orthologous target pairs with shared active compounds and comparison of organism-specific activity patterns.Evaluation of New Dihydrophthalazine-Appended 2,4-Diaminopyrimidines against Bacillus anthracis: Improved Syntheses Using a New Pincer Complex.Synthesis and biological activity of substituted 2,4-diaminopyrimidines that inhibit Bacillus anthracis.Comparative Study of the Frech Catalyst with Two Conventional Catalysts in the Heck Synthesis of 2,4-Diaminopyrimidine-based AntibioticsMicrowave-assisted Heck Synthesis of Substituted 2,4-Diaminopyrimidine-based AntibioticsDihydrofolate reductase as a therapeutic target for infectious diseases: opportunities and challenges.Classifying compound mechanism of action for linking whole cell phenotypes to molecular targets.
P2860
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P2860
In vitro efficacy of new antifolates against trimethoprim-resistant Bacillus anthracis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
In vitro efficacy of new antifolates against trimethoprim-resistant Bacillus anthracis.
@ast
In vitro efficacy of new antifolates against trimethoprim-resistant Bacillus anthracis.
@en
type
label
In vitro efficacy of new antifolates against trimethoprim-resistant Bacillus anthracis.
@ast
In vitro efficacy of new antifolates against trimethoprim-resistant Bacillus anthracis.
@en
prefLabel
In vitro efficacy of new antifolates against trimethoprim-resistant Bacillus anthracis.
@ast
In vitro efficacy of new antifolates against trimethoprim-resistant Bacillus anthracis.
@en
P2093
P2860
P356
P1476
In vitro efficacy of new antifolates against trimethoprim-resistant Bacillus anthracis.
@en
P2093
Esther W Barrow
Jürg Dreier
Philip C Bourne
Stefan Reinelt
William W Barrow
P2860
P304
P356
10.1128/AAC.00628-07
P407
P577
2007-09-17T00:00:00Z