Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch - Wikidata - wikimedia - TriplyDB

Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch

Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch

http://www.wikidata.org/entity/Q36324911

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Involvement of nectin in inactivation of integrin alpha(v)beta(3) after the establishment of cell-cell adhesion Phosphoinositide signaling regulates the exocyst complex and polarized integrin trafficking in directionally migrating cells Structure of the PTB domain of tensin1 and a model for its recruitment to fibrillar adhesions Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation Phosphoinositides: tiny lipids with giant impact on cell regulation Cross-Talk between Shp1 and PIPKIγ Controls Leukocyte Recruitment.An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding The Structure of an Interdomain Complex That Regulates Talin Activity Molecular Basis for Association of PIPKI -p90 with Clathrin Adaptor AP-2 Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3.PIP kinases define PI4,5P₂signaling specificity by association with effectors A computational analysis of the dynamic roles of talin, Dok1, and PIPKI for integrin activation Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila.Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.Isoform 5 of PIPKIγ regulates the endosomal trafficking and degradation of E-cadherin.Significance of talin in cancer progression and metastasis.Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer.The final steps of integrin activation: the end game A role for talin in presynaptic function.The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton.PIP5KI gamma is required for cardiovascular and neuronal development EZH2 regulates neuronal differentiation of mesenchymal stem cells through PIP5K1C-dependent calcium signaling Targeting type Iγ phosphatidylinositol phosphate kinase inhibits breast cancer metastasis Phosphatidylinositol Phosphate 5-Kinase Iγ and Phosphoinositide 3-Kinase/Akt Signaling Couple to Promote Oncogenic Growth.The interplay between Src and integrins in normal and tumor biology.Type I gamma phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migration Integrin activation by talin.A spatial model for integrin clustering as a result of feedback between integrin activation and integrin binding Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases.Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools.Structure and mechanics of integrin-based cell adhesion.A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family.Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration.Endosomal type Iγ PIP 5-kinase controls EGF receptor lysosomal sorting Out, in and back again: PtdIns(4,5)P(2) regulates cadherin trafficking in epithelial morphogenesis.Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis.Clathrin regulates the association of PIPKIgamma661 with the AP-2 adaptor beta2 appendage.Structural and biophysical properties of the integrin-associated cytoskeletal protein talin.

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P2860

Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch

http://www.wikidata.org/entity/Q36324911

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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Tyrosine phosphorylation of ty ...... lates an integrin-talin switch

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Tyrosine phosphorylation of ty ...... lates an integrin-talin switch

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Tyrosine phosphorylation of ty ...... lates an integrin-talin switch

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Tyrosine phosphorylation of ty ...... lates an integrin-talin switch

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Tyrosine phosphorylation of ty ...... lates an integrin-talin switch

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Tyrosine phosphorylation of ty ...... lates an integrin-talin switch

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Ari J Firestone

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Deane F Mosher

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Kun Ling

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Michael D Schaller

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Renee L Doughman

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Richard A Anderson

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Shawn F Bairstow

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Vidhya V Iyer

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P2860

Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

Structural determinants of integrin recognition by talin

Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

The phosphotyrosine binding-like domain of talin activates integrins

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

Tyrosine phosphorylation of paxillin, FAK, and p130CAS: effects on cell spreading and migration

Integrins isolated from Rous sarcoma virus-transformed chicken embryo fibroblasts

Focal adhesions, contractility, and signaling

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6

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163

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14691141

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phosphorylation

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2173703

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