The Fab fragment of a directly activating monoclonal antibody that precipitates a disulfide-linked heterodimer from a helper T cell clone blocks activation by either allogeneic Ia or antigen and self-Ia.
about
Presence of epidermal-derived thymocyte activating factor/interleukin 1 in normal human stratum corneumStructural evidence of T cell xeno-reactivity in the absence of molecular mimicryTh1 CD4+ lymphocytes delete activated macrophages through the Fas/APO-1 antigen pathway.Expression of major histocompatibility complex class II and CD80 by gingival epithelial cells induces activation of CD4+ T cells in response to bacterial challengeIsolation of a murine Ly-6 cDNA reveals a new multigene family.Negative selection of thymocytes expressing the D10 TCRQuantifying aggregation of IgE-FcepsilonRI by multivalent antigenCoclustering of CD4 (L3T4) molecule with the T-cell receptor is induced by specific direct interaction of helper T cells and antigen-presenting cellsT cells with two functional antigen-specific receptorsAutocrine growth inhibition of a cloned line of helper T cellsSubtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides.Direct interactions between B and T lymphocytes bearing complementary receptors.Inhibition of Ly-6A antigen expression prevents T cell activation.Downregulation of T cell responses by antibodies to the T cell receptor.Induction of cytotoxic T lymphocytes by primary in vitro stimulation with peptidesDifferent superantigens interact with distinct sites in the Vbeta domain of a single T cell receptor.IgG Fab fragments forming bivalent complexes by a conformational mechanism that is reversible by osmolytes.Superactivation of an immune response triggered by oligomerized T cell epitopes.The murine bm12 gene conversion provides evidence that T cells recognize predominantly Ia conformation.A 20-kDa protein associated with the murine T-cell antigen receptor is phosphorylated in response to activation by antigen or concanavalin A.Involvement of I-J epitopes in the self- and allo-recognition sites of T cells: blocking of syngeneic and allogeneic mixed lymphocyte reaction-responder cells by monoclonal anti-I-J antibodies.CD4+ T cells: specificity and function.T-cell responses to Mls and to bacterial proteins that mimic its behavior.The co-receptor function of murine CD4.The T cell antigen receptor.Germline transcription of multiple TCR-Vbeta genes in cloned T-cell lines.Synthesis of linear and comb-like peptide constructs containing up to four copies of a T cell epitope and their capacity to stimulate T cells.Ly-6A is required for T cell receptor expression and protein tyrosine kinase fyn activity.The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules.Are there cellular superantigens?Epitope-specific differential modulations within the T-cell antigen receptor complex.On the nature of peptides involved in T cell alloreactivity.Stimulation of a subset of normal resting T lymphocytes by a monoclonal antibody to a crossreactive determinant of the human T cell antigen receptor.Structural, molecular and immunological properties of linear B-cell epitopes of Ro60KD autoantigen.Idiotypic multireactivity of 'natural' antibodies. 'Natural' anti-idiotypes also inhibit helper cells with cross-reactive clonotypes.Formation of TCR dimers/trimers as a crucial step for T cell activation.
P2860
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P2860
The Fab fragment of a directly activating monoclonal antibody that precipitates a disulfide-linked heterodimer from a helper T cell clone blocks activation by either allogeneic Ia or antigen and self-Ia.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
@wuu
1984年学术文章
@zh-cn
1984年学术文章
@zh-hans
1984年学术文章
@zh-my
1984年学术文章
@zh-sg
1984年學術文章
@yue
1984年學術文章
@zh
1984年學術文章
@zh-hant
name
The Fab fragment of a directly ...... eic Ia or antigen and self-Ia.
@ast
The Fab fragment of a directly ...... eic Ia or antigen and self-Ia.
@en
type
label
The Fab fragment of a directly ...... eic Ia or antigen and self-Ia.
@ast
The Fab fragment of a directly ...... eic Ia or antigen and self-Ia.
@en
prefLabel
The Fab fragment of a directly ...... eic Ia or antigen and self-Ia.
@ast
The Fab fragment of a directly ...... eic Ia or antigen and self-Ia.
@en
P2860
P356
P1476
The Fab fragment of a directly ...... eic Ia or antigen and self-Ia.
@en
P2093
P2860
P304
P356
10.1084/JEM.159.5.1397
P407
P577
1984-05-01T00:00:00Z