Monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by CD5+ B cells from patients with rheumatoid arthritis.
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Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70-Biotin IgM antibodies in human blood: a previously unknown factor eliciting false results in biotinylation-based immunoassaysCellular immune mechanisms in chronic autoimmune thrombocytopenic purpura (ATP).The frequency of homozygous deletion of a developmentally regulated Vh gene (Humhv3005) is increased in patients with chronic idiopathic thrombocytopenic purpura.Complement activating properties of monoreactive and polyreactive IgM rheumatoid factorsLow molecular weight IgM and CD5 B lymphocytes in rheumatoid arthritis.Natural antibodies and the host immune responses to xenografts.The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidencA monoclonal antibody extends the half-life of an anti-HIV oligodeoxynucleotide and targets it to CD4+ cells.Molecular approaches to the study of human B-cell and (auto)antibody repertoire generation and selection.Human B-1 cells take the stage.B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-alphaGAL-producing B-1 cellsB cell activation and HIV infection: protective or potentially detrimental response?Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro.Impact of the molecular form of immunoglobulin A on functional activity in defense against Streptococcus pneumoniaeAutoregulatory function of interleukin-10-producing pre-naïve B cells is defective in systemic lupus erythematosusRegulation of antibody production mediated by Fc gamma receptors, IgG binding factors, and IgG Fc-binding autoantibodies.High-affinity binding of remyelinating natural autoantibodies to myelin-mimicking lipid bilayers revealed by nanohole surface plasmon resonance.Heteroclitic polyclonal and monoclonal anti-Gm(a) and anti-Gm(g) human rheumatoid factors react with epitopes induced in Gm(a-), Gm(g-) IgG by interaction with antigen or by nonspecific aggregation. A possible mechanism for the in vivo generation ofIdentification and analysis of a novel human surface CD5- B lymphocyte subset producing natural antibodies.Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven responseExtensive and selective mutation of a rearranged VH5 gene in human B cell chronic lymphocytic leukemia.Aspects of adaptive host response in periodontitis.Complete sequence of the genes encoding the VH and VL regions of low- and high-affinity monoclonal IgM and IgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient.Clonal analysis of a human antibody response. Quantitation of precursors of antibody-producing cells and generation and characterization of monoclonal IgM, IgG, and IgA to rabies virusSignal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes.The broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies.VH3-21 B cells escape from a state of tolerance in rheumatoid arthritis and secrete rheumatoid factorAutoreactivity of serum immunoglobulin to periodontal tissue components: a pilot studyVH genes of human autoantibodies.B cells in periodontitis: friends or enemies?CD19 signaling is impaired in murine peritoneal and splenic B-1 B lymphocytesRheumatoid factors: clinical applications.Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility.Autoantibodies and antibacterial antibodies: from both sides now.Molecular determinants of polyreactive antibody binding: HCDR3 and cyclic peptides.Site-specific glycosylation of human immunoglobulin G is altered in four rheumatoid arthritis patients.Generation of Human Monoclonal Autoantibody-Producing Cell Lines by Epstein-Barr Virus Transformation of Autoreactive B Lymphocytes and by Somatic Cell Hybridization Techniques: Application to the Analysis of the Autoimmune B Cell Repertoire.FcμR in human B cell subsets in primary selective IgM deficiency, and regulation of FcμR and production of natural IgM antibodies by IGIV.Rheumatoid factors induce signaling from B cells, leading to Epstein-Barr virus and B-cell activation.
P2860
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P2860
Monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by CD5+ B cells from patients with rheumatoid arthritis.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
Monoreactive high affinity and ...... nts with rheumatoid arthritis.
@ast
Monoreactive high affinity and ...... nts with rheumatoid arthritis.
@en
type
label
Monoreactive high affinity and ...... nts with rheumatoid arthritis.
@ast
Monoreactive high affinity and ...... nts with rheumatoid arthritis.
@en
prefLabel
Monoreactive high affinity and ...... nts with rheumatoid arthritis.
@ast
Monoreactive high affinity and ...... nts with rheumatoid arthritis.
@en
P2093
P2860
P356
P1476
Monoreactive high affinity and ...... nts with rheumatoid arthritis.
@en
P2093
Burastero SE
Notkins AL
P2860
P304
P356
10.1084/JEM.168.6.1979
P407
P577
1988-12-01T00:00:00Z