Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene.
about
Structure and expression of the human immunoglobulin lambda genesAnalysis of mice with single and multiple copies of transgenes reveals a novel arrangement for the lambda5-VpreB1 locus control region.Clonal deletion of specific thymocytes by an immunoglobulin idiotype.Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in transThe published data.Molecular characterization of transgene-induced immunodeficiency in B-less mice using a novel quantitative limiting dilution polymerase chain reaction method.lambda 5, but not mu, is required for B cell maturation in a unique gamma 2b transgenic mouse line.Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: localization to the T-B interface of the splenic follicle.Crossing the SJL lambda locus into kappa-knockout mice reveals a dysfunction of the lambda 1-containing immunoglobulin receptor in B cell differentiationAllelic exclusion of immunoglobulin genes: models and mechanisms.Immunoglobulin somatic variation; studies of receptor editing in a human B cell lymphoma.Murine lambda gene rearrangements: the stochastic model prevails over the ordered model.B-less: a strain of profoundly B cell-deficient mice expressing a human lambda transgene.Immunoglobulin gamma 2b transgenes inhibit heavy chain gene rearrangement, but cannot promote B cell developmentExpression level of a transgenic lambda2 chain results in isotype exclusion and commitment to B1 cells.The C(H)1 and transmembrane domains of mu in the context of a gamma2b transgene do not suffice to promote B cell maturation.
P2860
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P2860
Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
Inhibition of immunoglobulin g ...... ssion of a lambda 2 transgene.
@ast
Inhibition of immunoglobulin g ...... ssion of a lambda 2 transgene.
@en
type
label
Inhibition of immunoglobulin g ...... ssion of a lambda 2 transgene.
@ast
Inhibition of immunoglobulin g ...... ssion of a lambda 2 transgene.
@en
prefLabel
Inhibition of immunoglobulin g ...... ssion of a lambda 2 transgene.
@ast
Inhibition of immunoglobulin g ...... ssion of a lambda 2 transgene.
@en
P2093
P2860
P356
P1476
Inhibition of immunoglobulin g ...... ssion of a lambda 2 transgene.
@en
P2093
L T Doglio
R Brinster
P2860
P304
P356
10.1084/JEM.169.6.1911
P407
P577
1989-06-01T00:00:00Z