Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: localization to the T-B interface of the splenic follicle.
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Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigensB cell abnormalities in systemic lupus erythematosusICOS expression by effector T cells influences the ability of regulatory T cells to inhibit anti-chromatin B cell responses in recipient mice.Multiple tolerance defects contribute to the breach of B cell tolerance in New Zealand Black chromosome 1 congenic miceReceptor editing in peripheral B cell tolerance.The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpointsGerminal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.B-lymphocyte homeostasis and BLyS-directed immunotherapy in transplantation.Efficient help for autoreactive B-cell activation requires CD4+ T-cell recognition of an agonist peptide at the effector stage.From T to B and back again: positive feedback in systemic autoimmune disease.Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen.CD154-CD40 interactions mediate differentiation to plasma cells in healthy individuals and persons with systemic lupus erythematosus.Consequences of receptor editing at the lambda locus: multireactivity and light chain secretion.Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM.Antigenic targets--workshop report.Cellular competition independent of BAFF/B lymphocyte stimulator results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartmentsA B-cell receptor-specific selection step governs immature to mature B cell differentiationTLR7 influences germinal center selection in murine SLE.Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production.Positive selection focuses the VH12 B-cell repertoire towards a single B1 specificity with survival function.Expansion of autoreactive unresponsive CD21-/low B cells in Sjögren's syndrome-associated lymphoproliferation.A protective role for innate immunity in systemic lupus erythematosus.Apoptotic marginal zone deletion of anti-Sm/ribonucleoprotein B cellsComplement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clonesThe regulation and activation of lupus-associated B cells.Autoantigen-specific B-cell depletion overcomes failed immune tolerance in type 1 diabetesLoss of the proapoptotic protein, Bim, breaks B cell anergyAutoreactive marginal zone B cells are spontaneously activated but lymph node B cells require T cell helpThe Yaa locus and IFN-α fine-tune germinal center B cell selection in murine systemic lupus erythematosusAntigen-specific suppression of humoral immunity by anergic Ars/A1 B cells.MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells.Secondary heavy chain rearrangement: a mechanism for generating anti-double-stranded DNA B cells.Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice.Spontaneous follicular exclusion of SHP1-deficient B cells is conditional on the presence of competitor wild-type B cells.Abortive proliferation of rare T cells induced by direct or indirect antigen presentation by rare B cells in vivo.B-cell anergy: from transgenic models to naturally occurring anergic B cells?Autoantibody production in lpr/lpr gld/gld mice reflects accumulation of CD4+ effector cells that are resistant to regulatory T cell activity.ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity.In vivo BLyS/BAFF neutralization ameliorates islet-directed autoimmunity in nonobese diabetic mice.Early preplasma cells define a tolerance checkpoint for autoreactive B cells.
P2860
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P2860
Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: localization to the T-B interface of the splenic follicle.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Regulation of anti-double-stra ...... rface of the splenic follicle.
@ast
Regulation of anti-double-stra ...... rface of the splenic follicle.
@en
type
label
Regulation of anti-double-stra ...... rface of the splenic follicle.
@ast
Regulation of anti-double-stra ...... rface of the splenic follicle.
@en
prefLabel
Regulation of anti-double-stra ...... rface of the splenic follicle.
@ast
Regulation of anti-double-stra ...... rface of the splenic follicle.
@en
P2093
P2860
P356
P1476
Regulation of anti-double-stra ...... rface of the splenic follicle.
@en
P2093
P2860
P304
P356
10.1084/JEM.186.8.1257
P407
P577
1997-10-01T00:00:00Z