Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2-/- mice
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Organic Nitrate Therapy, Nitrate Tolerance, and Nitrate-Induced Endothelial Dysfunction: Emphasis on Redox Biology and Oxidative StressVascular Bioactivation of Nitroglycerin by Aldehyde Dehydrogenase-2: REACTION INTERMEDIATES REVEALED BY CRYSTALLOGRAPHY AND MASS SPECTROMETRYNitrates and nitrites in the treatment of ischemic cardiac diseaseOrganic nitrates and nitrate resistance in diabetes: the role of vascular dysfunction and oxidative stress with emphasis on antioxidant properties of pentaerithrityl tetranitrate.The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and glucotoxicityA new class of organic nitrates: investigations on bioactivation, tolerance and cross-tolerance phenomena.Pharmacological induction of vascular extracellular superoxide dismutase expression in vivo.Effect of oral organic nitrates on expression and activity of vascular soluble guanylyl cyclaseOrganic nitrate metabolism and action: toward a unifying hypothesis and the future-a dedication to Professor Leslie Z. Benet.The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and troublesDifferent effects of ascorbate deprivation and classical vascular nitrate tolerance on aldehyde dehydrogenase-catalysed bioactivation of nitroglycerin.Non-hemodynamic effects of organic nitrates and the distinctive characteristics of pentaerithrityl tetranitrate.Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction.Characteristics of aldehyde dehydrogenase 2 (Aldh2) knockout mice.Regulation of human mitochondrial aldehyde dehydrogenase (ALDH-2) activity by electrophiles in vitro.Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1.Chronic therapy with isosorbide-5-mononitrate causes endothelial dysfunction, oxidative stress, and a marked increase in vascular endothelin-1 expression.Chronic protection against ischemia and reperfusion-induced endothelial dysfunction during therapy with different organic nitrates.Basic in vitro Characterization of the Vasodilatory Potential of 2-Aminoethyl Nitrate Fixed-Dose Combinations with Cilostazol, Metoprolol and Valsartan.
P2860
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P2860
Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2-/- mice
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2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年學術文章
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name
Number of nitrate groups deter ...... oncept study in ALDH-2-/- mice
@ast
Number of nitrate groups deter ...... oncept study in ALDH-2-/- mice
@en
type
label
Number of nitrate groups deter ...... oncept study in ALDH-2-/- mice
@ast
Number of nitrate groups deter ...... oncept study in ALDH-2-/- mice
@en
prefLabel
Number of nitrate groups deter ...... oncept study in ALDH-2-/- mice
@ast
Number of nitrate groups deter ...... oncept study in ALDH-2-/- mice
@en
P2093
P2860
P356
P1476
Number of nitrate groups deter ...... oncept study in ALDH-2-/- mice
@en
P2093
A L Kleschyov
K J Lackner
L Steinhoff
P2860
P304
P356
10.1038/SJ.BJP.0707116
P407
P577
2007-01-15T00:00:00Z