Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin.
about
Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variantNon-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamilyNO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potentialOrganic Nitrate Therapy, Nitrate Tolerance, and Nitrate-Induced Endothelial Dysfunction: Emphasis on Redox Biology and Oxidative StressGlu504Lys Single Nucleotide Polymorphism of Aldehyde Dehydrogenase 2 Gene and the Risk of Human DiseasesAldehyde dehydrogenases in cellular responses to oxidative/electrophilic stressStructural and Functional Consequences of Coenzyme Binding to the Inactive Asian Variant of Mitochondrial Aldehyde Dehydrogenase: ROLES OF RESIDUES 475 AND 487Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variantDeveloping precision medicine for people of East Asian descentMitochondrial oxidative stress and nitrate tolerance--comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SOD+/- mice.Aldehyde dehydrogenase 2 in cardiac protection: a new therapeutic target?Mitochondrial aldehyde dehydrogenase and cardiac diseases.The ALDH2 rs671 polymorphism affects post-stroke epilepsy susceptibility and plasma 4-HNE levels.Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.A natural variant of obestatin, Q90L, inhibits ghrelin's action on food intake and GH secretion and targets NPY and GHRH neurons in mice.Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK/p53 pathway in miceAcetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancersPost-translational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications.Differential effects of organic nitrates on arterial diameter among healthy Japanese participants with different mitochondrial aldehyde dehydrogenase 2 genotypes: randomised crossover trial.Differential metabolism of organic nitrates by aldehyde dehydrogenase 1a1 and 2: substrate selectivity, enzyme inactivation, and active cysteine sites.A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variantCharacterization of the mechanism and magnitude of cytoglobin-mediated nitrite reduction and nitric oxide generation under anaerobic conditionsNumber of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2-/- miceThe role of ALDH2 and ADH1B polymorphism in alcohol consumption and stroke in Han Chinese.Nitroglycerin use in myocardial infarction patientsEffect of aldehyde dehydrogenase 2 gene polymorphism on hemodynamics after nitroglycerin intervention in Northern Chinese Han population.The case-only test for gene-environment interaction is not uniformly powerful: an empirical exampleAssociation between Carotid Intima-media Thickness and Aldehyde Dehydrogenase 2 Glu504Lys Polymorphism in Chinese Han with Essential HypertensionAldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaqueDevelopment of a prediction model and estimation of cumulative risk for upper aerodigestive tract cancer on the basis of the aldehyde dehydrogenase 2 genotype and alcohol consumption in a Japanese population.Meta-Analysis on the Association of ALDH2 Polymorphisms and Type 2 Diabetic Mellitus, Diabetic RetinopathyModulating nitric oxide signaling in the CNS for Alzheimer's disease therapy.Angina pectoris: current therapy and future treatment options.Molecular epidemiology, and possible real-world applications in breast cancer.Changes in aldehyde dehydrogenase 2 expression in rat blood vessels during glyceryl trinitrate tolerance development and reversal.Aldehyde dehydrogenase-2 (ALDH2) opposes hepatocellular carcinoma progression by regulating AMP-activated protein kinase signaling in mice.Vasodilator Therapy: Nitrates and Nicorandil.Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1.Structure SNP (StSNP): a web server for mapping and modeling nsSNPs on protein structures with linkage to metabolic pathways.Nitroglycerin-mediated S-nitrosylation of proteins: a field comes full cycle.
P2860
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P2860
Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Mitochondrial aldehyde dehydro ...... y of sublingual nitroglycerin.
@ast
Mitochondrial aldehyde dehydro ...... y of sublingual nitroglycerin.
@en
Mitochondrial aldehyde dehydrogenase-2
@nl
type
label
Mitochondrial aldehyde dehydro ...... y of sublingual nitroglycerin.
@ast
Mitochondrial aldehyde dehydro ...... y of sublingual nitroglycerin.
@en
Mitochondrial aldehyde dehydrogenase-2
@nl
prefLabel
Mitochondrial aldehyde dehydro ...... y of sublingual nitroglycerin.
@ast
Mitochondrial aldehyde dehydro ...... y of sublingual nitroglycerin.
@en
Mitochondrial aldehyde dehydrogenase-2
@nl
P2093
P2860
P356
P1476
Mitochondrial aldehyde dehydro ...... cy of sublingual nitroglycerin
@en
P2093
Chunhong Shao
Congjian Xu
Daniel W Nebert
Donald C Harrison
Haihui Sheng
P2860
P304
P356
10.1172/JCI26564
P407
P577
2006-01-26T00:00:00Z