Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination.
about
SMAR1 and Cux/CDP modulate chromatin and act as negative regulators of the TCRbeta enhancer (Ebeta)G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemiaMechanics of T cell receptor gene rearrangementLocus control regionsLong-Range Regulation of V(D)J Recombinationαβ T cell receptors as predictors of health and diseaseE proteins are required to activate germline transcription of the TCR Vbeta8.2 geneGenomic organization and recombinational unit duplication-driven evolution of ovine and bovine T cell receptor gamma loci.Initiation of V(D)J recombination by Dbeta-associated recombination signal sequences: a critical control point in TCRbeta gene assemblyGenomic analysis reveals extensive gene duplication within the bovine TRB locus.Memories of lost enhancersTranscription-dependent mobilization of nucleosomes at accessible TCR gene segments in vivo.Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes.Regulation of V(D)J recombination: a dominant role for promoter positioning in gene segment accessibility.Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination.Antigen receptor allelic exclusion: an update and reappraisalGene segment selection in V(D)J recombination: accessibility and beyond.The center of accessibility: Dβ control of V(D)J recombinationLineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element.A multistep mechanism for the activation of rearrangement in the immune systemA barrier-type insulator forms a boundary between active and inactive chromatin at the murine TCRβ locusDifferential regulation of proximal and distal Vbeta segments upstream of a functional VDJbeta1 rearrangement upon beta-selectionRegulating antigen-receptor gene assembly.Regulation of T-cell receptor beta-chain gene assembly by recombination signals: the beyond 12/23 restriction.How to keep V(D)J recombination under control.Monoallelic gene expression: a repertoire of recurrent themes.Enforcing order within a complex locus: current perspectives on the control of V(D)J recombination at the murine T-cell receptor alpha/delta locus.Influence of a CTCF-Dependent Insulator on Multiple Aspects of Enhancer-Mediated Chromatin OrganizationAntigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4.An ectopic CTCF-dependent transcriptional insulator influences the choice of Vβ gene segments for VDJ recombination at TCRβ locus.Chromosomal position of a VH gene segment determines its activation and inactivation as a substrate for V(D)J recombination.V(D)J recombination becomes accessibleInsertion of phosphoglycerine kinase (PGK)-neo 5' of Jlambda1 dramatically enhances VJlambda1 rearrangementTurning T-cell receptor beta recombination on and off: more questions than answers.Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structureEpigenetics and the adaptive immune responseExpression of T-cell receptor genes during early T-cell development.The T cell receptor beta enhancer promotes access and pairing of Dbeta and Jbeta gene segments during V(D)J recombinationVbeta cluster sequences reduce the frequency of primary Vbeta2 and Vbeta14 rearrangements.PU.1 regulates TCR expression by modulating GATA-3 activity.
P2860
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P2860
Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Chromatin remodeling by the T ...... TCR-beta locus recombination.
@ast
Chromatin remodeling by the T ...... TCR-beta locus recombination.
@en
type
label
Chromatin remodeling by the T ...... TCR-beta locus recombination.
@ast
Chromatin remodeling by the T ...... TCR-beta locus recombination.
@en
prefLabel
Chromatin remodeling by the T ...... TCR-beta locus recombination.
@ast
Chromatin remodeling by the T ...... TCR-beta locus recombination.
@en
P2093
P2860
P356
P1476
Chromatin remodeling by the T ...... TCR-beta locus recombination.
@en
P2093
P2860
P304
P356
10.1084/JEM.192.5.625
P407
P577
2000-09-01T00:00:00Z