Autoreactive B cells in the marginal zone that express dual receptors
about
Immunological aspects in chronic lymphocytic leukemia (CLL) developmentSecondary receptor editing in the generation of autoimmunityB cell receptor editing in tolerance and autoimmunityMarginal-zone B cellsRemarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemiaHumanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities.Augmented B lymphocyte response to antigen in the absence of antigen-induced B lymphocyte signaling in an IgG-transgenic mouse lineTwo distinct populations of H chain-edited B cells show differential surrogate L chain dependence.Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic toleranceIdentification of autoreactive B cells with labeled nucleosomesGerminal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.Homeostatic regulation of marginal zone B cells by invariant natural killer T cells.Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity.CD4+ T cells and CD40 participate in selection and homeostasis of peripheral B cells.Disrupted Mer receptor tyrosine kinase expression leads to enhanced MZ B-cell responses.Central B-cell tolerance: where selection begins.Analysis of expressed and non-expressed IGK locus rearrangements in chronic lymphocytic leukemia.Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen.Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity.B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemiaAlternative mechanisms of receptor editing in autoreactive B cells.Consequences of receptor editing at the lambda locus: multireactivity and light chain secretion.Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production.B-cell antigen-receptor signalling in lymphocyte development.Generation of B cell memory to the bacterial polysaccharide alpha-1,3 dextran.Positive selection of natural poly-reactive B cells in the periphery occurs independent of heavy chain allelic inclusionB-cell homeostasis, competition, resources, and positive selection by self-antigens.Development and selection of marginal zone B cells.Tolerance-induced receptor selection: scope, sensitivity, locus specificity, and relationship to lymphocyte-positive selection.Selection of B lymphocytes in the periphery is determined by the functional capacity of the B cell antigen receptorRoles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus.Predominant role for activation-induced cytidine deaminase in generating IgG anti-nucleosomal antibodies of murine SLE.Surrogate light chain expressing human peripheral B cells produce self-reactive antibodies.VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection.B-cell tolerance defects in the B6.Aec1/2 mouse model of Sjögren's syndrome.Apoptotic marginal zone deletion of anti-Sm/ribonucleoprotein B cellsInhibitory oligodeoxynucleotides - therapeutic promise for systemic autoimmune diseases?The regulation and activation of lupus-associated B cells.Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome.
P2860
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P2860
Autoreactive B cells in the marginal zone that express dual receptors
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Autoreactive B cells in the marginal zone that express dual receptors
@ast
Autoreactive B cells in the marginal zone that express dual receptors
@en
type
label
Autoreactive B cells in the marginal zone that express dual receptors
@ast
Autoreactive B cells in the marginal zone that express dual receptors
@en
prefLabel
Autoreactive B cells in the marginal zone that express dual receptors
@ast
Autoreactive B cells in the marginal zone that express dual receptors
@en
P2093
P2860
P356
P1476
Autoreactive B cells in the marginal zone that express dual receptors
@en
P2093
P2860
P304
P356
10.1084/JEM.20011453
P407
P577
2002-01-01T00:00:00Z