Phosphoinositide 3-kinase lipid products regulate ATP-dependent transport by sister of P-glycoprotein and multidrug resistance associated protein 2 in bile canalicular membrane vesicles - Wikidata - wikimedia - TriplyDB

Phosphoinositide 3-kinase lipid products regulate ATP-dependent transport by sister of P-glycoprotein and multidrug resistance associated protein 2 in bile canalicular membrane vesicles

Phosphoinositide 3-kinase lipid products regulate ATP-dependent transport by sister of P-glycoprotein and multidrug resistance associated protein 2 in bile canalicular membrane vesicles

http://www.wikidata.org/entity/Q36371975

about

Bile acid transporters in health and disease Liver dysfunction and phosphatidylinositol-3-kinase signalling in early sepsis: experimental studies in rodent models of peritonitis Cross-talk between signalling pathways and the multidrug resistant protein MDR-1 Newly synthesized canalicular ABC transporters are directly targeted from the Golgi to the hepatocyte apical domain in rat liver Cross-talk between protein kinases Czeta and B in cyclic AMP-mediated sodium taurocholate co-transporting polypeptide translocation in hepatocytes Transporters on demand: intrahepatic pools of canalicular ATP binding cassette transporters in rat liver.Akt signaling regulates side population cell phenotype via Bcrp1 translocation.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancer Unique functional and structural properties of the LRRK2 protein ATP-binding pocket.Hepatic pharmacokinetics of taurocholate in the normal and cholestatic rat liver Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.Evaluation of 11C-acetate and 18F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma.Structural and functional hepatocyte polarity and liver disease.Vps34p differentially regulates endocytosis from the apical and basolateral domains in polarized hepatic cells.Transporters on demand: intracellular reservoirs and cycling of bile canalicular ABC transporters.Hepatocyte polarity Sex-dependent disposition of acetaminophen sulfate and glucuronide in the in situ perfused mouse liver.Separation of insulin signaling into distinct GLUT4 translocation and activation steps.Aquaporins: their role in cholestatic liver disease.Overexpression of c-Met and CD44v6 receptors contributes to autocrine TGF-β1 signaling in interstitial lung disease Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells.Mechanism by which cAMP activates PI3-kinase and increases bile acid secretion in WIF-B9 cells.Role of the PI3K/PKB signaling pathway in cAMP-mediated translocation of rat liver Ntcp.Constitutively active phosphatidylinositol 3-kinase and AKT are sufficient to stimulate the epithelial Na+/H+ exchanger 3.Protein kinase B/Akt mediates cAMP- and cell swelling-stimulated Na+/taurocholate cotransport and Ntcp translocation.Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly.Glucagon induces the gene expression of aquaporin-8 but not that of aquaporin-9 water channels in the rat hepatocyte.Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets.Mechanisms by which cAMP increases bile acid secretion in rat liver and canalicular membrane vesicles.Subcellular localization of the ABCG2 transporter in normal and malignant human gallbladder epithelium.Ursodeoxycholic acid stabilizes the bile salt export pump in the apical membrane in MDCK II cells.Phosphoinositide 3-kinase is involved in the glucagon-induced translocation of aquaporin-8 to hepatocyte plasma membrane.Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver.Transforming growth factor β1 (TGFβ1) regulates CD44V6 expression and activity through extracellular signal-regulated kinase (ERK)-induced EGR1 in pulmonary fibrogenic fibroblasts.Involvement of a cyclic adenosine monophosphate-dependent signal in the diet-induced canalicular trafficking of adenosine triphosphate-binding cassette transporter g5/g8.

P2860

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P2860

Phosphoinositide 3-kinase lipid products regulate ATP-dependent transport by sister of P-glycoprotein and multidrug resistance associated protein 2 in bile canalicular membrane vesicles

http://www.wikidata.org/entity/Q36371975

description

1999 nî lūn-bûn

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1999年の論文

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

@zh-sg

1999年學術文章

@yue

1999年學術文章

@zh

1999年學術文章

@zh-hant

name

Phosphoinositide 3-kinase lipi ...... canalicular membrane vesicles

@ast

Phosphoinositide 3-kinase lipi ...... canalicular membrane vesicles

@en

type

label

Phosphoinositide 3-kinase lipi ...... canalicular membrane vesicles

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Phosphoinositide 3-kinase lipi ...... canalicular membrane vesicles

@en

prefLabel

Phosphoinositide 3-kinase lipi ...... canalicular membrane vesicles

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Phosphoinositide 3-kinase lipi ...... canalicular membrane vesicles

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P1433

Q36371975-B0D9ECCC-14BD-48A6-9FD6-B56EDEEA1ADE

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P2860

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PNAS.96.10.5814

P1433

Proceedings of the National Academy of Sciences of the United States of America

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Phosphoinositide 3-kinase lipi ...... canalicular membrane vesicles

@en

P2093

I M Arias

http://www.w3.org/2001/XMLSchema#string

L Varticovski

http://www.w3.org/2001/XMLSchema#string

P Ujházy

http://www.w3.org/2001/XMLSchema#string

S Misra

http://www.w3.org/2001/XMLSchema#string

P2860

Purification and characterization of phosphoinositide 3-kinase from rat liver

Cloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinase

Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

Oncogenes and signal transduction

Phosphoinositide kinases

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5814-5819

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scholarly article

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10.1073/PNAS.96.10.5814

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P433

10

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96

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1999-05-01T00:00:00Z

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12979625

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10318967

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P921

multiple drug resistance

P932

21943

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