Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin - Wikidata - wikimedia - TriplyDB

Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin

Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin

http://www.wikidata.org/entity/Q36374195

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Uncoupling transcription from covalent histone modification.Single cell visualization of yeast gene expression shows correlation of epigenetic switching between multiple heterochromatic regions through multiple generations The role of multiple marks in epigenetic silencing and the emergence of a stable bivalent chromatin state Competition between Heterochromatic Loci Allows the Abundance of the Silencing Protein, Sir4, to Regulate de novo Assembly of Heterochromatin.The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae.Epigenetics in Saccharomyces cerevisiae.The Ino80 complex prevents invasion of euchromatin into silent chromatin.PRB1 is required for clipping of the histone H3 N terminal tail in Saccharomyces cerevisiae.Silencing is noisy: population and cell level noise in telomere-adjacent genes is dependent on telomere position and sir2.DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.Breaking an epigenetic chromatin switch: curious features of hysteresis in Saccharomyces cerevisiae telomeric silencing.In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.Cooperative stabilization of the SIR complex provides robust epigenetic memory in a model of SIR silencing in Saccharomyces cerevisiae.Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.Hypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere Binding Proteins.Histone H3 N-terminal acetylation sites especially K14 are important for rDNA silencing and aging.Heterochromatic gene silencing by activator interference and a transcription elongation barrier.Something silent this way forms: the functional organization of the repressive nuclear compartment.The mre11 A470 alleles influence the hereditability and the segregation of telosomes in Saccharomyces cerevisiae.Detection of an altered heterochromatin structure in the absence of the nucleotide excision repair protein Rad4 in Saccharomyces cerevisiae.Recruitment and allosteric stimulation of a histone deubiquitinating enzyme during heterochromatin assembly.The interplay of histone H2B ubiquitination with budding and fission yeast heterochromatin.Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals.The INO80 remodeller in transcription, replication and repair.TERRA and the histone methyltransferase Dot1 cooperate to regulate senescence in budding yeast.Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods.

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Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin

http://www.wikidata.org/entity/Q36374195

description

2012 nî lūn-bûn

@nan

2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Mechanism for epigenetic varie ...... east telomeric heterochromatin

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Mechanism for epigenetic varie ...... east telomeric heterochromatin

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type

label

Mechanism for epigenetic varie ...... east telomeric heterochromatin

@ast

Mechanism for epigenetic varie ...... east telomeric heterochromatin

@en

prefLabel

Mechanism for epigenetic varie ...... east telomeric heterochromatin

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Mechanism for epigenetic varie ...... east telomeric heterochromatin

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Genes & Development

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Mechanism for epigenetic varie ...... east telomeric heterochromatin

@en

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Benjamin G Kuryan

http://www.w3.org/2001/XMLSchema#string

Chunying Song

http://www.w3.org/2001/XMLSchema#string

Michael Carey

http://www.w3.org/2001/XMLSchema#string

Michael Grunstein

http://www.w3.org/2001/XMLSchema#string

Nancy Nga Huynh Tran

http://www.w3.org/2001/XMLSchema#string

Tasuku Kitada

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Yong Xue

http://www.w3.org/2001/XMLSchema#string

P2860

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

RNA polymerase II-TFIIB structure and mechanism of transcription initiation

Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79

Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 A Resolution

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B.

Multiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae.

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin

Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast.

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2443-2455

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scholarly article

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10.1101/GAD.201095.112

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21

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26

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23124068

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3490002

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