Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes.
about
Hepatitis C virus non-structural protein NS3 interacts with LMP7, a component of the immunoproteasome, and affects its proteasome activityIFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient response26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide.PI31 is a modulator of proteasome formation and antigen processingMHC class I antigen processing and presenting machinery: organization, function, and defects in tumor cellsImmunoproteasomes: structure, function, and antigen presentationStealth and cunning: hepatitis B and hepatitis C viruses.Liver-directed gamma interferon gene delivery in chronic hepatitis C.Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infectionDifferential global structural changes in the core particle of yeast and mouse proteasome induced by ligand bindingDiscrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products.Global analysis of proteasomal substrate specificity using positional-scanning libraries of covalent inhibitors.The proteasome complex and the maintenance of pluripotency: sustain the fate by mopping up?Intrahepatic T cells in hepatitis B: viral control versus liver cell injury.Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic miceSearching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes.Reduction in ATP levels triggers immunoproteasome activation by the 11S (PA28) regulator during early antiviral response mediated by IFNβ in mouse pancreatic β-cells.Proteasomes shape the repertoire of T cells participating in antigen-specific immune responses.Ongoing coxsackievirus myocarditis is associated with increased formation and activity of myocardial immunoproteasomesRole of immunoproteasome catalytic subunits in the immune response to hepatitis B virusGeneration of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII.Hepatitis C virus mutation affects proteasomal epitope processingProteomic identification of immunoproteasome accumulation in formalin-fixed rodent spinal cords with experimental autoimmune encephalomyelitisInterferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing.Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens.The production of a new MAGE-3 peptide presented to cytolytic T lymphocytes by HLA-B40 requires the immunoproteasomeImmunoproteasome Activation During Early Antiviral Response in Mouse Pancreatic β-cells: New Insights into Auto-antigen Generation in Type I Diabetes?Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in a protein kinase R-dependent mannerMolecular mechanisms of IFN-gamma to up-regulate MHC class I antigen processing and presentation.The role of the proteasome in the generation of MHC class I ligands and immune responses.Emerging roles of immunoproteasomes beyond MHC class I antigen processing.Proteasome subtypes and regulators in the processing of antigenic peptides presented by class I molecules of the major histocompatibility complex.Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.IRF-1 mediates upregulation of LMP7 by IFN-gamma and concerted expression of immunosubunits of the proteasome.Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation.PA28 and the proteasome immunosubunits play a central and independent role in the production of MHC class I-binding peptides in vivo.Differences in the production of spliced antigenic peptides by the standard proteasome and the immunoproteasome.Identification of a TAP-independent, immunoproteasome-dependent CD8+ T-cell epitope in Epstein-Barr virus latent membrane protein 2.A kinetic model of vertebrate 20S proteasome accounting for the generation of major proteolytic fragments from oligomeric peptide substrates.A mathematical model of protein degradation by the proteasome.
P2860
Q24300867-12FF03C2-7F87-49CE-9F36-D514D5EE0C4EQ24531439-1B5F0041-1C24-417D-B189-86ED64703EC4Q24535312-5ED7CC11-8A43-4C40-A6BC-7B90A38E0A70Q24540374-D5375FF6-65B7-4C43-A066-A0594F3C18BAQ26866479-B404156F-7A90-4E52-A704-0C3C7D40C735Q27024527-64D2247F-EDAE-43D1-8766-CD0ED20379C6Q27470232-1E4CBDFF-90B6-41CB-85A9-A46C81077E3BQ27472673-7E64075D-47D2-4A48-80D6-1A2AF36BAF80Q27477499-0F2B3FDA-F3A7-4CED-AA72-CFA4C9942872Q27684495-3B4D3928-B72C-4E71-8FF0-FC3277272DF5Q30685494-1D614176-8E5F-4109-BB45-99BC031E0EF8Q30983359-A50C42F0-C1EC-460F-AF5D-8E3DD50D365CQ33673764-6D751EEA-D31F-4BDA-98B7-C7537C9A45ABQ33894481-CF40157B-4561-4A21-970B-BCE557924BE9Q33905980-1328F6C3-23FB-40B7-9C4E-01CEB72A5779Q34465900-8689448E-AB11-4620-9A0D-717558CB7150Q34577021-D7D22471-DD75-4E5F-B6E1-1C199FBF6524Q34596859-C9A3D110-126B-471E-AF25-45C83D1F43C2Q35088241-8520AB24-64D0-4455-AC90-81B94E006B9EQ35634949-C18E2CB5-E197-4D88-89DE-2DB2E6D4AFE0Q35821221-F3D036D3-E0CC-406F-BA6E-86D0BABF6B68Q35835376-6256A381-666B-490A-A66F-695494CE1A6BQ35854395-21737EDD-6CD4-4A25-A79F-B6914084FD19Q36266425-8829C2F3-E02C-439A-A5A1-814FF5F87BEBQ36369164-801D434B-DF77-4A98-8525-C100CDEC522EQ36369920-52B29A92-98E9-4F6D-8DD9-BAA8BECF319BQ37098480-7B986309-A9ED-4EE8-B67A-2C6ADB15CBC0Q37463918-EB4571A4-9CEA-4211-8427-685B138989DDQ37610453-B1646F7A-5B64-462A-8721-CD3DC4F1905EQ37851052-404386AF-CDD0-4AFC-9B4F-000BB147DC59Q37989860-20267E58-F880-4039-8993-DFB6C252D0B2Q38269935-13A5DBD4-4556-4B0D-A41B-850BCA187E02Q38305306-A1DFA5DC-2E72-4BE6-92C5-8983775FA83DQ38326038-A37F71EC-C4EE-4DFD-905D-287CC00350C4Q38955527-10072438-5915-40E3-8FF4-246D7FF9ADEFQ39584224-53F7B62C-345E-4326-A08A-7013AB193671Q39616600-8B2882AE-57DB-4A1E-B498-348CAEA12C62Q39700355-8C917D3C-2CB7-4032-8831-AE4279E2CED4Q40169547-15E0F9AA-E1AF-4593-A04B-8EF70A4B136DQ40324090-E11F91FA-4775-432D-98AF-CE25AA1DCB86
P2860
Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Efficient generation of a hepa ...... features of immunoproteasomes.
@ast
Efficient generation of a hepa ...... features of immunoproteasomes.
@en
type
label
Efficient generation of a hepa ...... features of immunoproteasomes.
@ast
Efficient generation of a hepa ...... features of immunoproteasomes.
@en
prefLabel
Efficient generation of a hepa ...... features of immunoproteasomes.
@ast
Efficient generation of a hepa ...... features of immunoproteasomes.
@en
P2093
P2860
P356
P1476
Efficient generation of a hepa ...... features of immunoproteasomes.
@en
P2093
B Rehermann
P M Kloetzel
U Koszinowski
P2860
P304
P356
10.1084/JEM.191.3.503
P407
P577
2000-02-01T00:00:00Z