B-cell anergy: from transgenic models to naturally occurring anergic B cells? - Wikidata - wikimedia - TriplyDB

B-cell anergy: from transgenic models to naturally occurring anergic B cells?

B-cell anergy: from transgenic models to naturally occurring anergic B cells?

http://www.wikidata.org/entity/Q36887132

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Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphate Systemic Lupus Erythematosus: Molecular Mimicry between Anti-dsDNA CDR3 Idiotype, Microbial and Self Peptides-As Antigens for Th Cells MicroRNAs in B cell development and malignancy The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease Heterogeneity of B Cell Functions in Stroke-Related Risk, Prevention, Injury, and Repair The biology behind PI3K inhibition in chronic lymphocytic leukaemia Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells.Augmented B lymphocyte response to antigen in the absence of antigen-induced B lymphocyte signaling in an IgG-transgenic mouse line Kinetic modeling reveals a common death niche for newly formed and mature B cells Transiently antigen-primed B cells return to naive-like state in absence of T-cell help.Altered B cell signalling in autoimmunity.B cells and type 1 diabetes ...in mice and men.B cell receptor signaling-based index as a biomarker for the loss of peripheral immune tolerance in autoreactive B cells in rheumatoid arthritis.Encoding immunological memory in the initiation of B-cell receptor signaling Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment The impact of CDK inhibition in human malignancies associated with pronounced defects in apoptosis: advantages of multi-targeting small molecules.Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes.Molecular underpinning of B-cell anergy.Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia.Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK.Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing.Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.Natural IgM prevents autoimmunity by enforcing B cell central tolerance induction Establishment of murine gammaherpesvirus latency in B cells is not a stochastic event.B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance.Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy.Expansion of autoreactive unresponsive CD21-/low B cells in Sjögren's syndrome-associated lymphoproliferation.Reversing Tolerance in Isotype Switch-Competent Anti-Insulin B Lymphocytes.B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens.Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones Retention of anergy and inhibition of antibody responses during acute γ herpesvirus 68 infection Endogenous antigen tunes the responsiveness of naive B cells but not T cells Receptor cross-talk spatially restricts p-ERK during TLR4 stimulation of autoreactive B cells.Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen.Presence of Rheumatoid Factor during Chronic HCV Infection Is Associated with Expansion of Mature Activated Memory B-Cells that Are Hypo-Responsive to B-Cell Receptor Stimulation and Persist during the Early Stage of IFN Free Therapy.BCR and co-receptor crosstalk facilitate the positive selection of self-reactive transitional B cells.Virus-like display of a neo-self antigen reverses B cell anergy in a B cell receptor transgenic mouse model.B Cells, Antibodies, and More.

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B-cell anergy: from transgenic models to naturally occurring anergic B cells?

http://www.wikidata.org/entity/Q36887132

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2007 nî lūn-bûn

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B-cell anergy: from transgenic models to naturally occurring anergic B cells?

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B-cell anergy: from transgenic models to naturally occurring anergic B cells?

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Nature Reviews Immunology

P1476

B-cell anergy: from transgenic models to naturally occurring anergic B cells?

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P2093

Barbara J Vilen

http://www.w3.org/2001/XMLSchema#string

John C Cambier

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Kevin T Merrell

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Stephen B Gauld

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P2860

Inhibition of the B cell by CD22: a requirement for Lyn

Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity

Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology

Predominant autoantibody production by early human B cell precursors

Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive.

Correlation of 9G4 idiotope with disease activity in patients with systemic lupus erythematosus

Anergy and not clonal ignorance determines the fate of B cells that recognize a physiological autoantigen.

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633-643

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10.1038/NRI2133

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8

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7

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2007-07-20T00:00:00Z

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1045570821

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17641666

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3714009

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