Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.
about
Protein kinase C signaling and cell cycle regulationSonic hedgehog negatively regulates pre-TCR-induced differentiation by a Gli2-dependent mechanismShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis.CXCR4 acts as a costimulator during thymic beta-selection.Cytosolic sequestration of Prep1 influences early stages of T cell development.SWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cellsRoles of the NF-kappaB pathway in lymphocyte development and function.Akt1 and Akt2 promote peripheral B-cell maturation and survival.T cell receptor CDR3 sequence but not recognition characteristics distinguish autoreactive effector and Foxp3(+) regulatory T cells.The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement.TCF1 and beta-catenin regulate T cell development and functionThe catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival.Notch dimerization is required for leukemogenesis and T-cell development.ATM influences the efficiency of TCRβ rearrangement, subsequent TCRβ-dependent T cell development, and generation of the pre-selection TCRβ CDR3 repertoire.Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.The RhoA transcriptional program in pre-T cells.Regulation of gene expression dynamics during developmental transitions by the Ikaros transcription factor.Asymmetric cell division during T cell development controls downstream fate.The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1.Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent.Lunatic fringe enhances competition for delta-like Notch ligands but does not overcome defective pre-TCR signaling during thymocyte beta-selection in vivo.Loss of TCR-beta F1 and/or EZRIN expression is associated with unfavorable prognosis in nodal peripheral T-cell lymphomas.Critical roles of the PI3K/Akt signaling pathway in T cell developmentRegulation of lymphocyte progenitor survival by the proapoptotic activities of Bim and BidPre-TCR-induced beta-catenin facilitates traversal through beta-selectionIkaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus.NFAT5 induction by the pre-T-cell receptor serves as a selective survival signal in T-lymphocyte developmentActivins and inhibins: novel regulators of thymocyte developmentSustained expression of pre-TCR induced beta-catenin in post-beta-selection thymocytes blocks T cell developmentCD117+CD44+ Stem T Cells Develop in the Thymus and Potently Suppress T-cell Proliferation by Modulating the CTLA-4 Pathway.Rho-GTPases as key regulators of T lymphocyte biology.Transcription factors and target genes of pre-TCR signaling.Developmental arrest of T cells in Rpl22-deficient mice is dependent upon multiple p53 effectorsPhospholipase Cγ1 is required for pre-TCR signal transduction and pre-T cell developmentThe atypical MAPK ERK3 controls positive selection of thymocytes.LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cellsCutting edge: rescue of pre-TCR but not mature TCR signaling in mice expressing membrane-targeted SLP-76.Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiencyVisualization of the earliest steps of gammadelta T cell development in the adult thymus.
P2860
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P2860
Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.
@ast
Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.
@en
type
label
Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.
@ast
Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.
@en
prefLabel
Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.
@ast
Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.
@en
P2093
P2860
P1476
Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor
@en
P2093
Adolfo Ferrando
Iannis Aifantis
Malay Mandal
Tomas Vilimas
P2860
P304
P356
10.1111/J.0105-2896.2006.00343.X
P577
2006-02-01T00:00:00Z