The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.
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Integrin engagement regulates monocyte differentiation through the forkhead transcription factor Foxp1Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrinThe structure of the two amino-terminal domains of human ICAM-1 suggests how it functions as a rhinovirus receptor and as an LFA-1 integrin ligandThe adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18)A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and plateletsCharacterization of the function of intercellular adhesion molecule (ICAM)-3 and comparison with ICAM-1 and ICAM-2 in immune responsesInflammation and vascular injury: basic discovery to drug developmentNeutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis.Structure and allosteric regulation of the X 2 integrin I domainStructural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3Neutrophil Integrins and Matrix Ligands and NET ReleaseBiology and structure of leukocyte β 2 integrins and their role in inflammationAssociation of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive stateDistinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2A binding interface on the I domain of lymphocyte function-associated antigen-1 (LFA-1) required for specific interaction with intercellular adhesion molecule 1 (ICAM-1)Neutrophil activation status in stable coronary artery disease.Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytesTolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cellsStructural basis of integrin regulation and signalingDifferential effects of serum heat treatment on chemotaxis and phagocytosis by human neutrophils.Extracellular polysaccharides produced by Ganoderma formosanum stimulate macrophage activation via multiple pattern-recognition receptorsAmino acid residues in the PSI domain and cysteine-rich repeats of the integrin beta2 subunit that restrain activation of the integrin alpha(X)beta(2).Characteristics of cation binding to the I domains of LFA-1 and MAC-1. The LFA-1 I domain contains a Ca2+-binding site.Superoxide anion generation in human milk macrophages: opsonin-dependent versus opsonin-independent stimulation compared with blood monocytes.Peptides derived from the complementarity-determining regions of anti-Mac-1 antibodies block intercellular adhesion molecule-1 interaction with Mac-1.Combinatorial libraries against libraries for selecting neoepitope activation-specific antibodies.Lectin site interaction with capsular polysaccharide mediates nonimmune phagocytosis of type III group B streptococci.The intracellular bacterium Rhodococcus equi requires Mac-1 to bind to mammalian cells.The alphaMbeta2 integrin and its role in neutrophil function.Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases.Dendritic cells transmit human immunodeficiency virus type 1 to monocytes and monocyte-derived macrophages.Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα.Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAMActivation of hepatic stellate cells after phagocytosis of lymphocytes: A novel pathway of fibrogenesis.Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils.Interaction of Leishmania gp63 with cellular receptors for fibronectinNonopsonic phagocytosis of zymosan and Mycobacterium kansasii by CR3 (CD11b/CD18) involves distinct molecular determinants and is or is not coupled with NADPH oxidase activationMechanism and implications of CXCR4-mediated integrin activation by Porphyromonas gingivalis.Conservation of the human integrin-type beta-propeller domain in bacteria.Lymphocyte adhesion to Candida albicans
P2860
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P2860
The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
The I domain is a major recogn ...... our distinct adhesion ligands.
@ast
The I domain is a major recogn ...... our distinct adhesion ligands.
@en
type
label
The I domain is a major recogn ...... our distinct adhesion ligands.
@ast
The I domain is a major recogn ...... our distinct adhesion ligands.
@en
prefLabel
The I domain is a major recogn ...... our distinct adhesion ligands.
@ast
The I domain is a major recogn ...... our distinct adhesion ligands.
@en
P2093
P2860
P4510
P356
P1476
The I domain is a major recogn ...... four distinct adhesion ligands
@en
P2093
J Garcia-Aguilar
J K Bickford
M S Diamond
T A Springer
P2860
P304
P356
10.1083/JCB.120.4.1031
P407
P577
1993-02-01T00:00:00Z