An alternate pathway for T cell development supported by the bone marrow microenvironment: recapitulation of thymic maturation
about
T lymphoid differentiation in human bone marrowLymphoid development from stem cells and the common lymphocyte progenitors.Expression of IL-5 alters bone metabolism and induces ossification of the spleen in transgenic mice.Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway.Bone marrow NK1.1(-) and NK1.1(+) T cells reciprocally regulate acute graft versus host disease.The effect of graft-versus-host disease on T cell production and homeostasis.Identification of lymphomyeloid primitive progenitor cells in fresh human cord blood and in the marrow of nonobese diabetic-severe combined immunodeficient (NOD-SCID) mice transplanted with human CD34(+) cord blood cellsDirect evidence for thymic function in adult humans.Identification of an early T cell progenitor for a pathway of T cell maturation in the bone marrow.Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host diseaseRegulation of normal and leukemic stem cells through cytokine signaling and the microenvironment.A bone marrow-derived stroma cell line, ST2, can support the differentiation of fetal thymocytes from the CD4+ CD8+ double negative to the CD4+ CD8+ double positive differentiation stage in vitro.The road ended up at stem cells.B-cell development: one problem, multiple solutions.Amplification of T cells from human cord blood in serum-deprived culture stimulated with stem cell factor, interleukin-7 and interleukin-2.T-cell and natural killer cell development in thymectomized Xenopus
P2860
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P2860
An alternate pathway for T cell development supported by the bone marrow microenvironment: recapitulation of thymic maturation
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
An alternate pathway for T cel ...... itulation of thymic maturation
@ast
An alternate pathway for T cel ...... itulation of thymic maturation
@en
type
label
An alternate pathway for T cel ...... itulation of thymic maturation
@ast
An alternate pathway for T cel ...... itulation of thymic maturation
@en
prefLabel
An alternate pathway for T cel ...... itulation of thymic maturation
@ast
An alternate pathway for T cel ...... itulation of thymic maturation
@en
P2093
P2860
P356
P1476
An alternate pathway for T cel ...... itulation of thymic maturation
@en
P2093
I L Weissman
M E García-Ojeda
S Dejbakhsh-Jones
P2860
P304
P356
10.1084/JEM.187.11.1813
P407
P577
1998-06-01T00:00:00Z