Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness - Wikidata - wikimedia - TriplyDB

Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness

Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness

http://www.wikidata.org/entity/Q36401550

about

Interleukin 9 induces expression of three cytokine signal inhibitors: cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signalling Pharmacotherapy and airway remodelling in asthma?Th2 cytokines and asthma. Interleukin-9 as a therapeutic target for asthma The puzzle of immune phenotypes of childhood asthma The mucosal immune system in the oral cavity-an orchestra of T cell diversity Treatment of allergic asthma: modulation of Th2 cells and their responses The development and in vivo function of T helper 9 cells Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9 ICOS co-stimulatory receptor is essential for T-cell activation and function Mucin biosynthesis: upregulation of core 2 beta 1,6 N-acetylglucosaminyltransferase by retinoic acid and Th2 cytokines in a human airway epithelial cell line Genetically manipulated mouse models of lung disease: potential and pitfalls IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells Noninvasive real-time measurement of nasal mucociliary clearance in mice by pinhole gamma scintigraphy.Severe respiratory syncytial virus bronchiolitis in infants is associated with reduced airway interferon gamma and substance P.IL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells.Regulation of IL-9 expression by IL-25 signaling.Cytokines in asthma.The use of knockouts to study determinants of airway hyperresponsiveness.Airway remodeling in asthma Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma.Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation.The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation.Airway remodeling in asthma. Unanswered questions.Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells.Importance of cytokines in murine allergic airway disease and human asthma.Chronic allergen challenge induces bronchial mast cell accumulation in BALB/c but not C57BL/6 mice and is independent of IL-9.Role of Tyk-2 in Th9 and Th17 cells in allergic asthma.Gene knockout models of asthma.Nitric oxide enhances Th9 cell differentiation and airway inflammation.Expression of IL-4 receptor alpha on smooth muscle cells is not necessary for development of experimental allergic asthma.Biotherapeutic targets for the treatment of allergic airway disease.Immune mechanisms in interstitial lung diseases.Type 1/Type 2 immunity in infectious diseases.TGF-beta induces IL-9 production from human Th17 cells.A brief history of IL-9 IL-9 and lung fibrosis: a Th2 good guy?Role of dendritic cells and Th2 lymphocytes in asthma: lessons from eosinophilic airway inflammation in the mouse.New insights into the role of cytokines in asthma Remodeling of the airway epithelium in asthma.IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.

P2860

Q24532238-9B7E3355-E3E4-41C7-AE32-4C38D07378BC Q24678822-163478FC-6913-4B0A-99E3-84300D5F0F98 Q24791881-B7768C71-8A34-4EC6-8ACF-9439017B46D1 Q26741068-EC10AAFF-D80D-416F-89EF-C5C13D10A35F Q26851091-57034883-F93C-4A48-91A0-07D281CCC67C Q27011823-4CBD733B-1590-49A5-A703-035FF88C9E92 Q28083375-220A7F77-0856-49B8-B23C-323A69453D54 Q28143141-B1FC88F1-CD49-4069-84EC-865E452ADB7C Q28187985-E223DE77-C80B-46BD-82AE-7FFCD5213F93 Q28297724-B2700C93-CE3F-4259-8CB0-649866F17C45 Q28388821-1420CFCF-8DD2-473F-99AA-525B082C784B Q28590243-021B6AB2-5D6C-40C6-AC32-C88F0B18BDE8 Q30494863-B6BD5DDD-245C-405C-9C41-CD54E98021EB Q33302897-E4F83B6C-B970-471F-B0ED-C864CEE15A44 Q33532650-4E4494B5-ECB3-42D6-9913-D09AA25D9A5A Q33682703-DA9AC7AD-8681-47BD-BBA3-72A78923F168 Q33717312-00C3C9D0-FE14-4046-9CE7-59E8AD28E660 Q33743160-1A21795F-48B6-48DB-8421-C8BDE5633C3E Q33753444-309A876C-7A75-408F-B976-18D07A25DC18 Q33831073-8ED2698A-DFAE-4419-9D85-48AFE376149D Q33835115-1BD7F9B2-35D3-4809-A623-A6996DAE2CFF Q33855162-642753F4-D8F2-4475-BA4F-9D9E41E2D501 Q33860254-0164551B-C45E-4055-89AB-839C9160506D Q33902052-37394806-F4EB-4DFF-B3C5-99D76F3EE5AD Q34003580-CAC0BDE1-FA9F-4EAA-AB23-2F6A1D6573CE Q34021220-ADF0A082-1E11-4267-A515-F742BDDDC34E Q34023371-8A2D133D-EEAE-4DBE-8F84-7CEC27DC2A57 Q34033726-6D2EDACE-EA61-4F8A-93EB-43AFCADD5243 Q34037524-2BE9472C-9CEB-4342-9407-FFE925AC985C Q34050010-2A2A234B-D69C-4B48-99A4-62E2F1EC44DC Q34058685-C7824692-9F16-4A55-BD0C-6215D70327CC Q34105088-9FE3B084-3647-442E-9461-6F8A1A48175D Q34105379-C7926E5A-CCB5-495C-BFC0-6409079EAC93 Q34113303-A14144A6-CDEB-488D-8B95-962247D822E9 Q34168144-27CD78D0-7F72-4D43-A17A-AA0161C16D4C Q34221323-12813F92-71ED-46AA-A202-89C3C0B4CBD1 Q34243622-A37BAE13-7401-40C5-82DE-9047D7763328 Q34321721-D7CA0F27-5FDC-44DE-9F8F-919BADE96543 Q34457559-19BBB369-E579-4388-8684-CCB74AD39BCF Q34589849-A1868C9E-FA39-49B5-BE67-0D9975002249

P2860

Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness

http://www.wikidata.org/entity/Q36401550

description

1998 nî lūn-bûn

@nan

1998年の論文

@ja

1998年学术文章

@wuu

1998年学术文章

@zh-cn

1998年学术文章

@zh-hans

1998年学术文章

@zh-my

1998年学术文章

@zh-sg

1998年學術文章

@yue

1998年學術文章

@zh

1998年學術文章

@zh-hant

name

Expression of interleukin 9 in ...... bronchial hyperresponsiveness

@ast

Expression of interleukin 9 in ...... bronchial hyperresponsiveness

@en

type

label

Expression of interleukin 9 in ...... bronchial hyperresponsiveness

@ast

Expression of interleukin 9 in ...... bronchial hyperresponsiveness

@en

prefLabel

Expression of interleukin 9 in ...... bronchial hyperresponsiveness

@ast

Expression of interleukin 9 in ...... bronchial hyperresponsiveness

@en

P1433

Q36401550-D3F0DDF0-B798-4041-A42B-CAAF46946C15

P1476

Q36401550-0A5BB8A5-2989-4E07-AE4A-DFDF28415741

P2093

Q36401550-2B8E3590-0CFF-4EFC-AE83-96964007A9B9

Q36401550-619EFFCF-8CB2-4FBD-8B80-3BB36FE44E73

Q36401550-88C442B8-9120-4DB9-B12E-66AC62EDBF70

Q36401550-95ED48E2-EAE0-4468-992E-7F09E1E427E8

P2860

Q36401550-0068D7B1-7169-4FEE-A9D5-A244AC72B7D0

Q36401550-061F3AA8-60EC-4847-994A-23823CE39EF5

Q36401550-0C5EEE73-7304-4436-8AFA-53594FFB9EFA

Q36401550-1487C6A4-0D87-4A93-AE95-983A1D1D5322

Q36401550-1833ADBA-0604-4B6C-A27A-3B5BB2B8D2E3

Q36401550-1AA5A38B-1F95-4128-86B6-754543BD8201

Q36401550-1C640730-270B-49EA-A231-0A78D93474FB

Q36401550-29487F3D-1B6D-4AA6-ADE0-3F78156D8A87

Q36401550-2BAAEBDD-F558-4291-8356-1051B487DF98

Q36401550-2D06CF8F-C964-4D3A-8396-091EF8141239

P304

Q36401550-CB167BFA-8252-408C-BC24-7ABD7EFFB73C

P31

Q36401550-477B3B9C-91A5-4F6D-A3B9-C48A71C0B840

P356

Q36401550-6794F0BE-9FEE-494C-A244-507FC63D4A61

P407

Q36401550-EF6BB2F2-79F6-480B-9003-BF433B18ABCD

P433

Q36401550-C3D2889F-7378-422C-8794-114EE64DD1E4

P478

Q36401550-C8E05F43-D557-436E-8FBF-310AC6430677

P577

Q36401550-395B3560-C9BC-4276-9C6B-CAD864BEF345

P5875

Q36401550-E860262C-D343-4A9B-A757-A03A9F521330

P698

Q36401550-CD20A867-A070-4038-A493-B08E881EDEDD

P921

Q36401550-02adac1b-b80f-4d25-96fa-fcf0919a28ff

Q36401550-492464BC-594C-4704-8AA3-D984EB6EF357

Q36401550-5E3B70C7-51AD-47CA-AB37-EBBB78BC7F3B

P932

Q36401550-BD874FEB-F235-44A0-AB8D-624769CC7234

P356

P1433

Journal of Experimental Medicine

P1476

Expression of interleukin 9 in ...... bronchial hyperresponsiveness

@en

P2093

G P Geba

http://www.w3.org/2001/XMLSchema#string

J A Rankin

http://www.w3.org/2001/XMLSchema#string

R A Flavell

http://www.w3.org/2001/XMLSchema#string

U A Temann

http://www.w3.org/2001/XMLSchema#string

P2860

Interleukin 9: a candidate gene for asthma

Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors

Molecular organization of the cytokine gene cluster, involving the human IL-3, IL-4, IL-5, and GM-CSF genes, on human chromosome 5

Human P40/IL-9. Expression in activated CD4+ T cells, genomic organization, and comparison with the mouse gene

Human interleukin-9: genomic sequence, chromosomal location, and sequences essential for its expression in human T-cell leukemia virus (HTLV)-I-transformed human T cells

Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity.

Peripheral blood eosinophil counts and bronchial responsiveness

Recombinant human interleukin 5 is a selective activator of human eosinophil function

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma

P304

1307-1320

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.188.7.1307

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

188

http://www.w3.org/2001/XMLSchema#string

P577

1998-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

13521689

http://www.w3.org/2001/XMLSchema#string

P698

9763610

http://www.w3.org/2001/XMLSchema#string

P921

P932

2212487

http://www.w3.org/2001/XMLSchema#string