Molecular pathogenesis of Fanconi anemia: recent progress.
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Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repairFANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasisUBE2W interacts with FANCL and regulates the monoubiquitination of Fanconi anemia protein FANCD2Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndromePALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility geneAssociation of BRCA1 mutations with occult primary ovarian insufficiency: a possible explanation for the link between infertility and breast/ovarian cancer risksMolecular pathogenesis and clinical management of Fanconi anemiaBMI1-mediated histone ubiquitylation promotes DNA double-strand break repairHow the fanconi anemia pathway guards the genomeIdentification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repairMechanisms of interstrand DNA crosslink repair and human disordersFanconi anemia pathway defects in inherited and sporadic cancersTargeting DNA damage response in cancer therapyInsights into Fanconi Anaemia from the structure of human FANCEA comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assayFANCI protein binds to DNA and interacts with FANCD2 to recognize branched structuresCellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insightsImpairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humansBRCA2 is required for neurogenesis and suppression of medulloblastomaThe Fanconi anemia pathway and ubiquitinATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway functionFanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction.Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.Oxidative stress resistance in Deinococcus radiodurans.FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.Cancer incidence in relatives of British Fanconi Anaemia patients.Current diagnosis of inherited bone marrow failure syndromes.Common Variable Immunodeficiency Caused by FANC Mutations.A novel germline PALB2 deletion in Polish breast and ovarian cancer patientsBACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control.Poly(ADP-ribose) polymerase-1 inhibition: preclinical and clinical development of synthetic lethality.Knockdown of mu-calpain in Fanconi anemia, FA-A, cells by siRNA restores alphaII spectrin levels and corrects chromosomal instability and defective DNA interstrand cross-link repair.The Fanconi anemia protein, FANCG, binds to the ERCC1-XPF endonuclease via its tetratricopeptide repeats and the central domain of ERCC1.Differential behaviour of normal, transformed and Fanconi's anemia lymphoblastoid cells to modeled microgravity.Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector.Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.Posttranslational modification of mammalian AP endonuclease (APE1).Understanding disease mechanisms with models of signaling pathway activities.Cancer stem cells are enriched in Fanconi anemia head and neck squamous cell carcinomas
P2860
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P2860
Molecular pathogenesis of Fanconi anemia: recent progress.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Molecular pathogenesis of Fanconi anemia: recent progress.
@ast
Molecular pathogenesis of Fanconi anemia: recent progress.
@en
type
label
Molecular pathogenesis of Fanconi anemia: recent progress.
@ast
Molecular pathogenesis of Fanconi anemia: recent progress.
@en
prefLabel
Molecular pathogenesis of Fanconi anemia: recent progress.
@ast
Molecular pathogenesis of Fanconi anemia: recent progress.
@en
P1433
P1476
Molecular pathogenesis of Fanconi anemia: recent progress.
@en
P2093
Alan D D'Andrea
Toshiyasu Taniguchi
P304
P356
10.1182/BLOOD-2005-10-4240
P407
P577
2006-02-21T00:00:00Z