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Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

http://www.wikidata.org/entity/Q36403978

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Cutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppression Cancer Stem Cell Hierarchy in Glioblastoma Multiforme Stem Cell Modeling of Core Binding Factor Acute Myeloid Leukemia Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function Hematopoietic stem cell niche maintenance during homeostasis and regeneration Advances in understanding the leukaemia microenvironment Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response Concise reviews: A stem cell apostasy: a tale of four H words Oncogenic Kras initiates leukemia in hematopoietic stem cells A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages.New IDH1 mutant inhibitors for treatment of acute myeloid leukemia Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2 Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells A mathematical model of cancer stem cell driven tumor initiation: implications of niche size and loss of homeostatic regulatory mechanisms Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104 MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.Flow cytometry analysis of murine hematopoietic stem cells.Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib Fibroblast growth factor 2 supports osteoblastic niche cells during hematopoietic homeostasis recovery after bone marrow suppression.CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells.CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells.Id1 restrains p21 expression to control endothelial progenitor cell formation.A novel assay to trace proliferation history in vivo reveals that enhanced divisional kinetics accompany loss of hematopoietic stem cell self-renewal Thrombopoietin and hematopoietic stem cells.PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function.Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance.Stem cell proliferation and quiescence--two sides of the same coin.Heterogeneity of non-cycling and cycling synchronized murine hematopoietic stem/progenitor cells Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells.Bone marrow vascular niche: home for hematopoietic stem cells.Tandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions.Selective enhancement of donor hematopoietic cell engraftment by the CXCR4 antagonist AMD3100 in a mouse transplantation model.Smurf2 regulates hematopoietic stem cell self-renewal and aging.Regulation of RB transcription in vivo by RB family members p53 regulates hematopoietic stem cell quiescence.The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS.

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P2860

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

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2005 nî lūn-bûn

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2005年学术文章

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Global analysis of proliferati ...... stem and progenitor cell fates

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Amy J Wagers

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Emmanuelle Passegué

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Irving L Weissman

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Wade C Anderson

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P2860

Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells

Molecular signatures of proliferation and quiescence in hematopoietic stem cells

Stem cells, cancer, and cancer stem cells

Stem cells: units of development, units of regeneration, and units in evolution

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G(2)/M transit and do not reenter G(0).

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