Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling.
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Molecular mechanisms of biological aging in intervertebral discsDisc in flames: Roles of TNF-α and IL-1β in intervertebral disc degenerationRole of cytokines in intervertebral disc degeneration: pain and disc contentHypoxia and tissue destruction in pulmonary TBProlyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells.FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells.Conditional knockout of prolyl hydroxylase domain protein 2 attenuates high fat-diet-induced cardiac dysfunction in mice.Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: evolving role of TonEBPEGR1 controls divergent cellular responses of distinctive nucleus pulposus cell typesSyndecan-4 in intervertebral disc and cartilage: Saint or synner?Cell signaling pathways related to pain receptors in the degenerated disk.Tumor necrosis factor-α potentiates long-term potentiation in the rat dentate gyrus after acute hypoxia.CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 integrins in nucleus pulposus cells: implications in intervertebral disc degeneration.An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes.VHL promotes immune response against renal cell carcinoma via NF-κB-dependent regulation of VCAM-1.Follistatin-like protein 1 promotes inflammatory reactions in nucleus pulposus cells by interacting with the MAPK and NFκB signaling pathways.Tumor necrosis factor-α: a key contributor to intervertebral disc degeneration.A role for TNFα in intervertebral disc degeneration: a non-recoverable catabolic shift.Hypoxia promotes the production and inhibits the destruction of human articular cartilage.Ghrelin protects against nucleus pulposus degeneration through inhibition of NF-κB signaling pathway and activation of Akt signaling pathway.Hepatocyte growth factor/c-met promotes proliferation, suppresses apoptosis, and improves matrix metabolism in rabbit nucleus pulposus cells in vitro.Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells.PHD3 is a transcriptional coactivator of HIF-1α in nucleus pulposus cells independent of the PKM2-JMJD5 axis.Nitric oxide mediates prolyl hydroxylase 3 expression in mesangial cells and in glomerulonephritis.Salubrinal Suppresses IL-17-Induced Upregulation of MMP-13 and Extracellular Matrix Degradation Through the NF-kB Pathway in Human Nucleus Pulposus Cells.Applying chlorogenic acid in an alginate scaffold of chondrocytes can improve the repair of damaged articular cartilage.Sesamin inhibits lipopolysaccharide-induced inflammation and extracellular matrix catabolism in rat intervertebral disc.TNF-α and TGF-β1 regulate Syndecan-4 expression in nucleus pulposus cells: role of the mitogen-activated protein kinase and NF-κB pathways.
P2860
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P2860
Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Prolyl hydroxylase 3 (PHD3) mo ...... ctor κB (NF-κB)/p65 signaling.
@ast
Prolyl hydroxylase 3 (PHD3) mo ...... ctor κB (NF-κB)/p65 signaling.
@en
type
label
Prolyl hydroxylase 3 (PHD3) mo ...... ctor κB (NF-κB)/p65 signaling.
@ast
Prolyl hydroxylase 3 (PHD3) mo ...... ctor κB (NF-κB)/p65 signaling.
@en
prefLabel
Prolyl hydroxylase 3 (PHD3) mo ...... ctor κB (NF-κB)/p65 signaling.
@ast
Prolyl hydroxylase 3 (PHD3) mo ...... ctor κB (NF-κB)/p65 signaling.
@en
P2093
P2860
P356
P1476
Prolyl hydroxylase 3 (PHD3) mo ...... ctor κB (NF-κB)/p65 signaling.
@en
P2093
Irving M Shapiro
Kazuhiro Chiba
Makarand V Risbud
Nobuyuki Fujita
Shilpa S Gogate
Yoshiaki Toyama
P2860
P304
39942-39953
P356
10.1074/JBC.M112.375964
P407
P577
2012-09-04T00:00:00Z