Mechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analogues
about
Phosphorylation and nuclear translocation of a regulator of G protein signaling (RGS10)RGS8 accelerates G-protein-mediated modulation of K+ currentsParticipation of nucleoside-diphosphate kinase in muscarinic K+ channel activation does not involve GTP formation.Receptor-independent activation of atrial muscarinic potassium channels in the absence of nucleotides.Voltage affects the dissociation rate constant of the m2 muscarinic receptor.Polyplexed flow cytometry protein interaction assay: a novel high-throughput screening paradigm for RGS protein inhibitorsMechanisms controlling cell size and shape during isotropic cell spreadingG-protein mediated gating of inward-rectifier K+ channels.Graded contribution of the Gbeta gamma binding domains to GIRK channel activation.Time course of receptor-channel coupling in frog sympathetic neurons.A model of the muscarinic receptor-induced changes in K(+)-current and action potentials in the bullfrog atrial cell.Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.Activators of G-protein signaling 3: a drug addiction molecular gateway.A membrane-delimited pathway of G-protein regulation of the guard-cell inward K+ channelA novel GTP-dependent mechanism of ileal muscarinic metabotropic channel desensitization.The nature and origin of spontaneous noise in G protein-gated ion channels.Rate-limiting steps in the beta-adrenergic stimulation of cardiac calcium currentRapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins.GTP-dependent regulation of myometrial KCa channels incorporated into lipid bilayers.Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq.RGS proteins reconstitute the rapid gating kinetics of gbetagamma-activated inwardly rectifying K+ channels.Coordinating speed and amplitude in G-protein signaling.Mechanisms of activity-dependent plasticity in cellular nitric oxide-cGMP signalingHeterologously expressed serotonin 1A receptors couple to muscarinic K+ channels in heartThe role of G proteins in transmembrane signalling.Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation.G proteins in reverse mode: receptor-mediated GTP release inhibits G protein and effector function.Speed of Ca2+ channel modulation by neurotransmitters in rat sympathetic neurons.G protein regulation of cardiac muscarinic potassium channel.Measurement of tissue transglutaminase activity in a permeabilized cell system: its regulation by Ca2+ and nucleotidesGbetagamma-activated inwardly rectifying K(+) (GIRK) channel activation kinetics via Galphai and Galphao-coupled receptors are determined by Galpha-specific interdomain interactions that affect GDP release rates.Effects of anions on the G protein-mediated activation of the muscarinic K+ channel in the cardiac atrial cell membrane. Intracellular chloride inhibition of the GTPase activity of GK.Regulation of Ca2+ current in frog ventricular cardiomyocytes by 5'-guanylylimidodiphosphate and acetylcholine.Nitric oxide donor SIN-1 inhibits mammalian cardiac calcium current through cGMP-dependent protein kinase.Induction of GD3/α1-adrenergic receptor/transglutaminase 2-mediated erythroid differentiation in chronic myelogenous leukemic K562 cellsEvidence of involvement of GIRK1/GIRK4 in long-term desensitization of cardiac muscarinic K+ channels.Changes of the responses of single sympathetic ganglionic neurones to substance P following desensitization.Modulation by 5-hydroxytryptamine of nicotinic acetylcholine responses recorded from an identified cockroach (Periplaneta americana) motoneuron.Slow inhibition of N-type calcium channels with GTP gamma S reflects the basal G protein-GDP turnover rate.An enzyme-linked receptor mechanism for nitric oxide-activated guanylyl cyclase.
P2860
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P2860
Mechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analogues
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
Mechanism of muscarinic recept ...... olysis-resistant GTP analogues
@ast
Mechanism of muscarinic recept ...... olysis-resistant GTP analogues
@en
type
label
Mechanism of muscarinic recept ...... olysis-resistant GTP analogues
@ast
Mechanism of muscarinic recept ...... olysis-resistant GTP analogues
@en
prefLabel
Mechanism of muscarinic recept ...... olysis-resistant GTP analogues
@ast
Mechanism of muscarinic recept ...... olysis-resistant GTP analogues
@en
P2860
P356
P1476
Mechanism of muscarinic recept ...... olysis-resistant GTP analogues
@en
P2093
G E Breitwieser
P2860
P304
P356
10.1085/JGP.91.4.469
P577
1988-04-01T00:00:00Z